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Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion.
Virology. 2007 Mar 30;360(1):105-19. doi: 10.1016/j.virol.2006.09.036. Epub 2006 Nov 7.
Virology. 2007.
PMID: 17084877
Free PMC article.
The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.
Dunfee RL, Thomas ER, Gorry PR, Wang J, Taylor J, Kunstman K, Wolinsky SM, Gabuzda D.
Dunfee RL, et al.
Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15160-5. doi: 10.1073/pnas.0605513103. Epub 2006 Oct 2.
Proc Natl Acad Sci U S A. 2006.
PMID: 17015824
Free PMC article.
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