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57 results

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Page 1
Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.
Wong C, Dakin RS, Williamson J, Newton J, Steven M, Colville S, Stavrou M, Gregory JM, Elliott E, Mehta AR, Chataway J, Swingler RJ, Parker RA, Weir CJ, Stallard N, Parmar MKB, Macleod MR, Pal S, Chandran S. Wong C, et al. Among authors: dakin rs. BMJ Open. 2022 Jul 7;12(7):e064173. doi: 10.1136/bmjopen-2022-064173. BMJ Open. 2022. PMID: 35798516 Free PMC article. Clinical Trial.
Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial.
Pal S, Chataway J, Swingler R, Macleod MR, Carragher NO, Hardingham G, Selvaraj BT, Smith C, Wong C, Newton J, Lyle D, Stenson A, Dakin RS, Ihenacho A, Colville S, Mehta AR, Stallard N, Carpenter JR, Parker RA, Keerie C, Weir CJ, Virgo B, Morris S, Waters N, Gray B, MacDonald D, MacDonald E, Parmar MKB, Chandran S; MND SMART Investigators. Pal S, et al. Among authors: dakin rs. Lancet Neurol. 2024 Nov;23(11):1097-1107. doi: 10.1016/S1474-4422(24)00326-0. Epub 2024 Sep 19. Lancet Neurol. 2024. PMID: 39307154 Free article. Clinical Trial.
Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective.
Wong C, Stavrou M, Elliott E, Gregory JM, Leigh N, Pinto AA, Williams TL, Chataway J, Swingler R, Parmar MKB, Stallard N, Weir CJ, Parker RA, Chaouch A, Hamdalla H, Ealing J, Gorrie G, Morrison I, Duncan C, Connelly P, Carod-Artal FJ, Davenport R, Reitboeck PG, Radunovic A, Srinivasan V, Preston J, Mehta AR, Leighton D, Glasmacher S, Beswick E, Williamson J, Stenson A, Weaver C, Newton J, Lyle D, Dakin R, Macleod M, Pal S, Chandran S. Wong C, et al. Among authors: dakin r. Brain Commun. 2021 Oct 23;3(4):fcab242. doi: 10.1093/braincomms/fcab242. eCollection 2021. Brain Commun. 2021. PMID: 34901853 Free PMC article. Review.
Systems biology as a framework to understand the physiological and endocrine bases of behavior and its evolution-From concepts to a case study in birds.
Fuxjager MJ, Ryder TB, Moody NM, Alfonso C, Balakrishnan CN, Barske J, Bosholn M, Boyle WA, Braun EL, Chiver I, Dakin R, Day LB, Driver R, Fusani L, Horton BM, Kimball RT, Lipshutz S, Mello CV, Miller ET, Webster MS, Wirthlin M, Wollman R, Moore IT, Schlinger BA. Fuxjager MJ, et al. Among authors: dakin r. Horm Behav. 2023 May;151:105340. doi: 10.1016/j.yhbeh.2023.105340. Epub 2023 Mar 16. Horm Behav. 2023. PMID: 36933440 Review.
57 results