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Page 1
Defining the clinical validity of genes reported to cause pulmonary arterial hypertension.
Welch CL, Aldred MA, Balachandar S, Dooijes D, Eichstaedt CA, Gräf S, Houweling AC, Machado RD, Pandya D, Prapa M, Shaukat M, Southgate L, Tenorio-Castano J; ClinGen PH VCEP; Chung WK; International Consortium for Genetic Studies in Pulmonary Arterial Hypertension (PAH-ICON) at the Pulmonary Vascular Research Institute (PVRI). Welch CL, et al. Genet Med. 2023 Nov;25(11):100925. doi: 10.1016/j.gim.2023.100925. Epub 2023 Jul 5. Genet Med. 2023. PMID: 37422716 Free PMC article.
Single-cell transcriptomics reveal diverging pathobiology and opportunities for precision targeting in scleroderma-associated versus idiopathic pulmonary arterial hypertension.
Tuhy T, Coursen JC, Graves T, Patatanian M, Cherry C, Niedermeyer SE, Khan SL, Rosen DT, Croglio MP, Elnashar M, Kolb TM, Mathai SC, Damico RL, Hassoun PM, Shimoda LA, Suresh K, Aldred MA, Simpson CE. Tuhy T, et al. Among authors: damico rl. bioRxiv [Preprint]. 2024 Oct 25:2024.10.25.620225. doi: 10.1101/2024.10.25.620225. bioRxiv. 2024. Update in: Circ Genom Precis Med. 2025 Aug;18(4):e004936. doi: 10.1161/CIRCGEN.124.004936. PMID: 39484590 Free PMC article. Updated. Preprint.
Prognostic Value of Echocardiographic Coupling Metrics in Systemic Sclerosis-Associated Pulmonary Vascular Disease.
Gami A, Jani VP, Mombeini H, Osgueritchian R, Cubero Salazar IM, Kauffman M, Simpson CE, Damico RL, Kolb TM, Shah AA, Mathai SC, Tedford RJ, Hsu S, Hassoun PM, Mukherjee M. Gami A, et al. Among authors: damico rl. J Am Soc Echocardiogr. 2025 Feb;38(2):115-126. doi: 10.1016/j.echo.2024.09.010. Epub 2024 Oct 1. J Am Soc Echocardiogr. 2025. PMID: 39362283
Lung Single-Cell Transcriptomics Reveal Diverging Pathobiology and Opportunities for Precision Targeting in Scleroderma-Associated Versus Idiopathic Pulmonary Arterial Hypertension.
Tuhy T, Coursen JC, Graves T, Patatanian M, Cherry C, Niedermeyer SE, Khan SL, Rosen DT, Croglio MP, Elnashar M, Kolb TM, Mathai SC, Damico RL, Hassoun PM, Shimoda LA, Suresh K, Aldred MA, Simpson CE. Tuhy T, et al. Among authors: damico rl. Circ Genom Precis Med. 2025 Aug;18(4):e004936. doi: 10.1161/CIRCGEN.124.004936. Epub 2025 Jul 21. Circ Genom Precis Med. 2025. PMID: 40686216 Free PMC article.
Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension.
Ambade AS, Naranjo M, Tuhy T, Yu R, Marimoutou M, Everett AD, Shimoda LA, Zimmerman SL, Cubero Salazar IM, Simpson CE, Tedford RJ, Hsu S, Hassoun PM, Damico RL. Ambade AS, et al. Among authors: damico rl. Am J Respir Cell Mol Biol. 2024 Sep;71(3):343-355. doi: 10.1165/rcmb.2024-0039OC. Am J Respir Cell Mol Biol. 2024. PMID: 38861354 Free PMC article.
Germline and somatic variants in DNMT3A and other clonal haematopoiesis of indeterminate potential genes contribute to pulmonary arterial hypertension.
Al-Qazazi R, Emon IM, Potus F, Martin AY, Lima PDA, Vlasschaert C, Ott BP, Chen KH, Wu D, Dasgupta A, Noordhof C, Jefferson L, Buttigieg MM, McNaughton AJM, Hindmarch CCT, Bick AG, Nichols WC, Chung WK, Hassoun PM, Damico RL, Zhu N, Shen Y, Rauh MJ, Archer SL. Al-Qazazi R, et al. Among authors: damico rl. Eur Heart J. 2025 Aug 29:ehaf611. doi: 10.1093/eurheartj/ehaf611. Online ahead of print. Eur Heart J. 2025. PMID: 40878867
Metabolomic Differences in Connective Tissue Disease-Associated Versus Idiopathic Pulmonary Arterial Hypertension in the PVDOMICS Cohort.
Simpson CE, Hemnes AR, Griffiths M, Grunig G, Tang WHW, Garcia JGN, Barnard J, Comhair SA, Damico RL, Mathai SC, Hassoun PM; PVDOMICS Study Group. Simpson CE, et al. Among authors: damico rl. Arthritis Rheumatol. 2023 Dec;75(12):2240-2251. doi: 10.1002/art.42632. Epub 2023 Oct 30. Arthritis Rheumatol. 2023. PMID: 37335853 Free PMC article.
61 results