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1988 1
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2020 13
2021 24
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105 results

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Page 1
ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms.
Riabov V, Xu Q, Schmitt N, Streuer A, Ge G, Bolanos L, Wunderlich M, Jann JC, Wein A, Altrock E, Demmerle M, Mukherjee S, Ali AM, Rapp F, Nowak V, Weimer N, Obländer J, Palme I, Göl M, Jawhar A, Darwich A, Wuchter P, Weiss C, Raza A, Foulks JM, Starczynowski DT, Yang FC, Metzgeroth G, Steiner L, Jawhar M, Hofmann WK, Nowak D. Riabov V, et al. Among authors: darwich a. Haematologica. 2024 May 1;109(5):1426-1438. doi: 10.3324/haematol.2023.282921. Haematologica. 2024. PMID: 37916386 Free PMC article.
T-cell-based breast cancer immunotherapy.
Pilipow K, Darwich A, Losurdo A. Pilipow K, et al. Among authors: darwich a. Semin Cancer Biol. 2021 Jul;72:90-101. doi: 10.1016/j.semcancer.2020.05.019. Epub 2020 May 31. Semin Cancer Biol. 2021. PMID: 32492452 Review.
Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes.
Schmitt N, Jann JC, Altrock E, Flach J, Danner J, Uhlig S, Streuer A, Knaflic A, Riabov V, Xu Q, Mehralivand A, Palme I, Nowak V, Obländer J, Weimer N, Haselmann V, Jawhar A, Darwich A, Weis CA, Marx A, Steiner L, Jawhar M, Metzgeroth G, Boch T, Nolte F, Hofmann WK, Nowak D. Schmitt N, et al. Among authors: darwich a. Leukemia. 2022 Jan;36(1):236-247. doi: 10.1038/s41375-021-01327-w. Epub 2021 Jun 25. Leukemia. 2022. PMID: 34172896 Free PMC article.
Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective.
Wilson CG, Aarons L, Augustijns P, Brouwers J, Darwich AS, De Waal T, Garbacz G, Hansmann S, Hoc D, Ivanova A, Koziolek M, Reppas C, Schick P, Vertzoni M, García-Horsman JA. Wilson CG, et al. Among authors: darwich as. Eur J Pharm Sci. 2022 May 1;172:106100. doi: 10.1016/j.ejps.2021.106100. Epub 2021 Dec 20. Eur J Pharm Sci. 2022. PMID: 34936937 Free article.
Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.
Darwich AS, Ogungbenro K, Vinks AA, Powell JR, Reny JL, Marsousi N, Daali Y, Fairman D, Cook J, Lesko LJ, McCune JS, Knibbe C, de Wildt SN, Leeder JS, Neely M, Zuppa AF, Vicini P, Aarons L, Johnson TN, Boiani J, Rostami-Hodjegan A. Darwich AS, et al. Clin Pharmacol Ther. 2017 May;101(5):646-656. doi: 10.1002/cpt.659. Epub 2017 Apr 4. Clin Pharmacol Ther. 2017. PMID: 28182269 Review.
Singleton-Merten syndrome: A rare cause of femoral head necrosis.
Assaf E, Bdeir M, Mohs E, Dally FJ, Gravius S, Weis CA, Darwich A. Assaf E, et al. Among authors: darwich a. Am J Med Genet A. 2021 Oct;185(10):3170-3175. doi: 10.1002/ajmg.a.62395. Epub 2021 Jun 30. Am J Med Genet A. 2021. PMID: 34189824
A modular and controllable T cell therapy platform for acute myeloid leukemia.
Benmebarek MR, Cadilha BL, Herrmann M, Lesch S, Schmitt S, Stoiber S, Darwich A, Augsberger C, Brauchle B, Rohrbacher L, Oner A, Seifert M, Schwerdtfeger M, Gottschlich A, Rataj F, Fenn NC, Klein C, Subklewe M, Endres S, Hopfner KP, Kobold S. Benmebarek MR, et al. Among authors: darwich a. Leukemia. 2021 Aug;35(8):2243-2257. doi: 10.1038/s41375-020-01109-w. Epub 2021 Jan 7. Leukemia. 2021. PMID: 33414484 Free PMC article.
The bispecific innate cell engager AFM28 eliminates CD123+ leukemic stem and progenitor cells in AML and MDS.
Schmitt N, Siegler JJ, Beck A, Müller T, Kozlowska I, Sarlang S, Reusch U, Knackmuss S, Medina-Echeverz J, Koch J, Ross T, Darwich A, Hoppe L, Abba M, Streuer A, Klein S, Hofmann WK, Gündner AL, Merz C, Endell J, Pahl J, Nowak D. Schmitt N, et al. Among authors: darwich a. Nat Commun. 2025 Aug 21;16(1):7793. doi: 10.1038/s41467-025-63069-y. Nat Commun. 2025. PMID: 40841539 Free PMC article.
105 results