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Page 1
Continuation vs Discontinuation of Renin-Angiotensin System Inhibitors Before Major Noncardiac Surgery: The Stop-or-Not Randomized Clinical Trial.
Legrand M, Falcone J, Cholley B, Charbonneau H, Delaporte A, Lemoine A, Garot M, Joosten A, Meistelman C, Cheron-Leroy D, Rives JP, Pastene B, Dewitte A, Sigaut S, Danguy des Deserts M, Truc C, Boisson M, Lasocki S, Cuvillon P, Schiff U, Jaber S, Le Guen M, Caillard A, Bar S, Pereira de Souza Neto E, Colas V, Dimache F, Girardot T, Jozefowicz E, Viquesnel S, Berthier F, Vicaut E, Gayat E; Stop-or-Not Trial Group. Legrand M, et al. JAMA. 2024 Sep 24;332(12):970-978. doi: 10.1001/jama.2024.17123. JAMA. 2024. PMID: 39212270 Free PMC article. Clinical Trial.
Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection.
Granton E, Brown L, Defaye M, Moazen P, Almblad H, Randall TE, Rich JD, Geppert A, Abdullah NS, Hassanabad MF, Hiroki CH, Farias R, Nguyen AP, Schubert C, Lou Y, Andonegui G, Iftinca M, Raju D, Vargas MA, Howell PL, Füzesi T, Bains J, Kurrasch D, Harrison JJ, Altier C, Yipp BG. Granton E, et al. Among authors: defaye m. Cell. 2024 Apr 11;187(8):1874-1888.e14. doi: 10.1016/j.cell.2024.03.001. Epub 2024 Mar 21. Cell. 2024. PMID: 38518773 Free article.
The gut microbiota promotes pain in fibromyalgia.
Cai W, Haddad M, Haddad R, Kesten I, Hoffman T, Laan R, Westfall S, Defaye M, Abdullah NS, Wong C, Brown N, Tansley S, Lister KC, Hooshmandi M, Wang F, Lorenzo LE, Hovhannisyan V, Ho-Tieng D, Kumar V, Sharif B, Thurairajah B, Fan J, Sahar T, Clayton C, Wu N, Zhang J, Bar-Yoseph H, Pitashny M, Krock E, Mogil JS, Prager-Khoutorsky M, Séguéla P, Altier C, King IL, De Koninck Y, Brereton NJB, Gonzalez E, Shir Y, Minerbi A, Khoutorsky A. Cai W, et al. Among authors: defaye m. Neuron. 2025 Jul 9;113(13):2161-2175.e13. doi: 10.1016/j.neuron.2025.03.032. Epub 2025 Apr 24. Neuron. 2025. PMID: 40280127 Free article.
Nociceptor neurons suppress alveolar macrophage-induced Siglec-F+ neutrophil-mediated inflammation to protect against pulmonary fibrosis.
Hiroki CH, Hassanabad MF, Defaye M, Sarden N, Bartlett A, Farias R, Nguyen AP, Guerrero-Fonseca IM, Yoon G, Brown L, Ma C, Yang H, Belke D, Fatehi Hassanabad A, McCoy C, Rosin NL, Orton DJ, Fedak PWM, Vallance BA, Yu H, Jacobson K, Khan N, Altier C, Kelly MM, Yipp BG. Hiroki CH, et al. Among authors: defaye m. Immunity. 2025 Aug 12;58(8):2054-2068.e6. doi: 10.1016/j.immuni.2025.05.002. Epub 2025 May 30. Immunity. 2025. PMID: 40449484
AhR/IL-22 pathway as new target for the treatment of post-infectious irritable bowel syndrome symptoms.
Meynier M, Baudu E, Rolhion N, Defaye M, Straube M, Daugey V, Modoux M, Wawrzyniak I, Delbac F, Villéger R, Méleine M, Borras Nogues E, Godfraind C, Barnich N, Ardid D, Poirier P, Sokol H, Chatel JM, Langella P, Livrelli V, Bonnet M, Carvalho FA. Meynier M, et al. Among authors: defaye m. Gut Microbes. 2022 Jan-Dec;14(1):2022997. doi: 10.1080/19490976.2021.2022997. Gut Microbes. 2022. PMID: 35090380 Free PMC article.
Neuroimmunophysiology of the gastrointestinal tract.
McKay DM, Defaye M, Rajeev S, MacNaughton WK, Nasser Y, Sharkey KA. McKay DM, et al. Among authors: defaye m. Am J Physiol Gastrointest Liver Physiol. 2024 Jun 1;326(6):G712-G725. doi: 10.1152/ajpgi.00075.2024. Epub 2024 Apr 16. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 38626403 Free PMC article. Review.
Sex-specific post-inflammatory dysbiosis mediates chronic visceral pain in colitis.
Arzamendi MJ, Habibyan YB, Defaye M, Shute A, Baggio CH, Chan R, Ohland C, Bihan DG, Lewis IA, Sharkey KA, McCoy KD, Altier C, Geuking MB, Nasser Y. Arzamendi MJ, et al. Among authors: defaye m. Gut Microbes. 2024 Jan-Dec;16(1):2409207. doi: 10.1080/19490976.2024.2409207. Epub 2024 Oct 3. Gut Microbes. 2024. PMID: 39360560 Free PMC article.
Induction of antiviral interferon-stimulated genes by neuronal STING promotes the resolution of pain in mice.
Defaye M, Bradaia A, Abdullah NS, Agosti F, Iftinca M, Delanne-Cuménal M, Soubeyre V, Svendsen K, Gill G, Ozmaeian A, Gheziel N, Martin J, Poulen G, Lonjon N, Vachiery-Lahaye F, Bauchet L, Basso L, Bourinet E, Chiu IM, Altier C. Defaye M, et al. J Clin Invest. 2024 Mar 19;134(9):e176474. doi: 10.1172/JCI176474. J Clin Invest. 2024. PMID: 38690737 Free PMC article.
Neural control of gut homeostasis.
Abdullah N, Defaye M, Altier C. Abdullah N, et al. Among authors: defaye m. Am J Physiol Gastrointest Liver Physiol. 2020 Dec 1;319(6):G718-G732. doi: 10.1152/ajpgi.00293.2020. Epub 2020 Oct 7. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 33026824 Free article. Review.
32 results