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Year Number of Results
1998 1
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41 results

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Page 1
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G; Genomics England Research Consortium; de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. Prentzell MT, et al. Among authors: demetriades c. Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25. Cell. 2021. PMID: 33497611 Free PMC article.
An Expert Consensus Statement on Biomarkers of Aging for Use in Intervention Studies.
Perri G, French C, Agostinis-Sobrinho C, Anand A, Antarianto RD, Arai Y, Baur JA, Cauli O, Clivaz-Duc M, Colloca G, Demetriades C, de Lucia C, Di Gessa G, Diniz BS, Dotchin CL, Eaglestone G, Elliott BT, Espeland MA, Ferrucci L, Fisher J, Grammatopoulos DK, Hardiany NS, Hassan-Smith Z, Hastings WJ, Jain S, Joshi PK, Katsila T, Kemp GJ, Khaiyat OA, Lamming DW, Gallegos JL, Madeo F, Maier AB, Martin-Ruiz C, Martins IJ, Mathers JC, Mattin LR, Merchant RA, Moskalev A, Neytchev O, Ni Lochlainn M, Owen CM, Phillips SM, Pratt J, Prokopidis K, Rattray NJW, Rúa-Alonso M, Schomburg L, Scott D, Shyam S, Sillanpää E, Tan MMC, Teh R, Tobin SW, Vila-Chã CJ, Vorluni L, Weber D, Welch A, Wilson D, Wilson T, Zhao T, Philippou E, Korolchuk VI, Shannon OM. Perri G, et al. Among authors: demetriades c. J Gerontol A Biol Sci Med Sci. 2025 Apr 7;80(5):glae297. doi: 10.1093/gerona/glae297. J Gerontol A Biol Sci Med Sci. 2025. PMID: 39708300 Free PMC article.
Codependencies of mTORC1 signaling and endolysosomal actin structures.
Priya A, Antoine-Bally S, Macé AS, Monteiro P, Sabatet V, Remy D, Dingli F, Loew D, Demetriades C, Gautreau AM, Chavrier P. Priya A, et al. Among authors: demetriades c. Sci Adv. 2023 Sep 15;9(37):eadd9084. doi: 10.1126/sciadv.add9084. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703363 Free PMC article.
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor.
Nicastro R, Brohée L, Alba J, Nüchel J, Figlia G, Kipschull S, Gollwitzer P, Romero-Pozuelo J, Fernandes SA, Lamprakis A, Vanni S, Teleman AA, De Virgilio C, Demetriades C. Nicastro R, et al. Among authors: demetriades c. Nat Cell Biol. 2023 Sep;25(9):1303-1318. doi: 10.1038/s41556-023-01198-6. Epub 2023 Aug 10. Nat Cell Biol. 2023. PMID: 37563253 Free PMC article.
mTORC1 activity negatively regulates human hair follicle growth and pigmentation.
Suzuki T, Chéret J, Scala FD, Akhundlu A, Gherardini J, Demetrius DL, O'Sullivan JDB, Kuka Epstein G, Bauman AJ, Demetriades C, Paus R. Suzuki T, et al. Among authors: demetriades c. EMBO Rep. 2023 Jul 5;24(7):e56574. doi: 10.15252/embr.202256574. Epub 2023 May 22. EMBO Rep. 2023. PMID: 37212043 Free PMC article.
Metabolic rewiring caused by mitochondrial dysfunction promotes mTORC1-dependent skeletal aging.
Bubb K, Etich J, Probst K, Parashar T, Schuetter M, Dethloff F, Reincke S, Nolte JL, Krüger M, Schlötzer-Schrehard U, Nüchel J, Demetriades C, Giavalisco P, Riemer J, Brachvogel B. Bubb K, et al. Among authors: demetriades c. Sci Adv. 2025 Apr 18;11(16):eads1842. doi: 10.1126/sciadv.ads1842. Epub 2025 Apr 18. Sci Adv. 2025. PMID: 40249823 Free PMC article.
Schizoaffective Disorder and Concurrent Rhabdomyolysis.
Varkey T, Demetriades C, Malluru N, Merhavy ZI, Simtion K, Garmer C, Zeitler C, Pyada R, Nguyen AM, Ding JB. Varkey T, et al. Among authors: demetriades c. Cureus. 2021 Nov 25;13(11):e19896. doi: 10.7759/cureus.19896. eCollection 2021 Nov. Cureus. 2021. PMID: 34976507 Free PMC article.
41 results