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Page 1
Profiling the genome and proteome of metabolic dysfunction-associated steatotic liver disease identifies potential therapeutic targets.
Liu J, Hu S, Chen L, Daly C, Prada Medina CA, Richardson TG, Traylor M, Dempster NJ, Mbasu R, Monfeuga T, Vujkovic M, Tsao PS, Lynch JA, Voight BF, Chang KM, Million VA, Cobbold JF, Tomlinson JW, van Duijn CM, Howson JMM. Liu J, et al. Among authors: dempster nj. medRxiv [Preprint]. 2023 Nov 30:2023.11.30.23299247. doi: 10.1101/2023.11.30.23299247. medRxiv. 2023. PMID: 38076879 Free PMC article. Preprint.
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease.
Nikolaou N, Gathercole LL, Marchand L, Althari S, Dempster NJ, Green CJ, van de Bunt M, McNeil C, Arvaniti A, Hughes BA, Sgromo B, Gillies RS, Marschall HU, Penning TM, Ryan J, Arlt W, Hodson L, Tomlinson JW. Nikolaou N, et al. Among authors: dempster nj. Metabolism. 2019 Oct;99:67-80. doi: 10.1016/j.metabol.2019.153947. Epub 2019 Jul 19. Metabolism. 2019. PMID: 31330134 Free PMC article.
Extensive weight loss reduces glycan age by altering IgG N-glycosylation.
Greto VL, Cvetko A, Štambuk T, Dempster NJ, Kifer D, Deriš H, Cindrić A, Vučković F, Falchi M, Gillies RS, Tomlinson JW, Gornik O, Sgromo B, Spector TD, Menni C, Geremia A, Arancibia-Cárcamo CV, Lauc G. Greto VL, et al. Among authors: dempster nj. Int J Obes (Lond). 2021 Jul;45(7):1521-1531. doi: 10.1038/s41366-021-00816-3. Epub 2021 May 3. Int J Obes (Lond). 2021. PMID: 33941843 Free PMC article.
AKR1D1 knockout mice develop a sex-dependent metabolic phenotype.
Gathercole LL, Nikolaou N, Harris SE, Arvaniti A, Poolman TM, Hazlehurst JM, Kratschmar DV, Todorčević M, Moolla A, Dempster N, Pink RC, Saikali MF, Bentley L, Penning TM, Ohlsson C, Cummins CL, Poutanen M, Odermatt A, Cox RD, Tomlinson JW. Gathercole LL, et al. Among authors: dempster n. J Endocrinol. 2022 Apr 13;253(3):97-113. doi: 10.1530/JOE-21-0280. J Endocrinol. 2022. PMID: 35318963 Free PMC article.
Phenothiazinium-fluoroquinolone drug conjugates.
Wainwright M, Shah A, Meegan K, Loughran C, Smith A, Valli N, Dempster N. Wainwright M, et al. Among authors: dempster n. Int J Antimicrob Agents. 2010 Apr;35(4):405-9. doi: 10.1016/j.ijantimicag.2009.11.022. Epub 2010 Jan 8. Int J Antimicrob Agents. 2010. PMID: 20060690
52 results