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Page 1
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.
Tabula Sapiens Consortium*; Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Culver RN, Cvijović I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kong W, Kumar ME, Kuo AH, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Oz… See abstract for full author list ➔ Tabula Sapiens Consortium*, et al. Among authors: detweiler am. Science. 2022 May 13;376(6594):eabl4896. doi: 10.1126/science.abl4896. Epub 2022 May 13. Science. 2022. PMID: 35549404 Free PMC article.
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.
Li H, Janssens J, De Waegeneer M, Kolluru SS, Davie K, Gardeux V, Saelens W, David FPA, Brbić M, Spanier K, Leskovec J, McLaughlin CN, Xie Q, Jones RC, Brueckner K, Shim J, Tattikota SG, Schnorrer F, Rust K, Nystul TG, Carvalho-Santos Z, Ribeiro C, Pal S, Mahadevaraju S, Przytycka TM, Allen AM, Goodwin SF, Berry CW, Fuller MT, White-Cooper H, Matunis EL, DiNardo S, Galenza A, O'Brien LE, Dow JAT; FCA Consortium§; Jasper H, Oliver B, Perrimon N, Deplancke B, Quake SR, Luo L, Aerts S, Agarwal D, Ahmed-Braimah Y, Arbeitman M, Ariss MM, Augsburger J, Ayush K, Baker CC, Banisch T, Birker K, Bodmer R, Bolival B, Brantley SE, Brill JA, Brown NC, Buehner NA, Cai XT, Cardoso-Figueiredo R, Casares F, Chang A, Clandinin TR, Crasta S, Desplan C, Detweiler AM, Dhakan DB, Donà E, Engert S, Floc'hlay S, George N, González-Segarra AJ, Groves AK, Gumbin S, Guo Y, Harris DE, Heifetz Y, Holtz SL, Horns F, Hudry B, Hung RJ, Jan YN, Jaszczak JS, Jefferis GSXE, Karkanias J, Karr TL, Katheder NS, Kezos J, Kim AA, Kim SK, Kockel L, Konstantinides N, Kornberg TB, Krause HM, Labott AT, Laturney M, Lehmann R, Leinwand S, Li J, Li JSS, Li K, Li K, Li L, Li T, Litovchenko M, Liu HH, Liu Y, Lu TC, Manni… See abstract for full author list ➔ Li H, et al. Among authors: detweiler am. Science. 2022 Mar 4;375(6584):eabk2432. doi: 10.1126/science.abk2432. Epub 2022 Mar 4. Science. 2022. PMID: 35239393 Free PMC article.
Early prediction of preeclampsia in pregnancy with cell-free RNA.
Moufarrej MN, Vorperian SK, Wong RJ, Campos AA, Quaintance CC, Sit RV, Tan M, Detweiler AM, Mekonen H, Neff NF, Baruch-Gravett C, Litch JA, Druzin ML, Winn VD, Shaw GM, Stevenson DK, Quake SR. Moufarrej MN, et al. Among authors: detweiler am. Nature. 2022 Feb;602(7898):689-694. doi: 10.1038/s41586-022-04410-z. Epub 2022 Feb 9. Nature. 2022. PMID: 35140405 Free PMC article.
A multimodal zebrafish developmental atlas reveals the state-transition dynamics of late-vertebrate pluripotent axial progenitors.
Lange M, Granados A, VijayKumar S, Bragantini J, Ancheta S, Kim YJ, Santhosh S, Borja M, Kobayashi H, McGeever E, Solak AC, Yang B, Zhao X, Liu Y, Detweiler AM, Paul S, Theodoro I, Mekonen H, Charlton C, Lao T, Banks R, Xiao S, Jacobo A, Balla K, Awayan K, D'Souza S, Haase R, Dizeux A, Pourquie O, Gómez-Sjöberg R, Huber G, Serra M, Neff N, Pisco AO, Royer LA. Lange M, et al. Among authors: detweiler am. Cell. 2024 Nov 14;187(23):6742-6759.e17. doi: 10.1016/j.cell.2024.09.047. Epub 2024 Oct 24. Cell. 2024. PMID: 39454574 Free article.
Comparative analysis of human and mouse ovaries across age.
Gaylord EA, Foecke MH, Samuel RM, Soygur B, Detweiler AM, McIntyre TI, Dorman LC, Borja M, Laird AE, Arjyal R, Du J, Gardner JM, Neff N, Fattahi F, Laird DJ. Gaylord EA, et al. Among authors: detweiler am. Science. 2025 Oct 9. doi: 10.1126/science.adx0659. Online ahead of print. Science. 2025. PMID: 41066539
Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.
Winkler J, Tan W, Diadhiou CM, McGinnis CS, Abbasi A, Hasnain S, Durney S, Atamaniuc E, Superville D, Awni L, Lee JV, Hinrichs JH, Wagner PS, Singh N, Hein MY, Borja M, Detweiler AM, Liu SY, Nanjaraj A, Sitarama V, Rugo HS, Neff N, Gartner ZJ, Oliveira Pisco A, Goga A, Darmanis S, Werb Z. Winkler J, et al. Among authors: detweiler am. J Clin Invest. 2024 Sep 3;134(17):e164227. doi: 10.1172/JCI164227. J Clin Invest. 2024. PMID: 39225101 Free PMC article.
Cell types of origin of the cell-free transcriptome.
Vorperian SK, Moufarrej MN; Tabula Sapiens Consortium; Quake SR. Vorperian SK, et al. Nat Biotechnol. 2022 Jun;40(6):855-861. doi: 10.1038/s41587-021-01188-9. Epub 2022 Feb 7. Nat Biotechnol. 2022. PMID: 35132263 Free PMC article.
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency.
Pavel-Dinu M, Gardner CL, Nakauchi Y, Kawai T, Delmonte OM, Palterer B, Bosticardo M, Pala F, Viel S, Malech HL, Ghanim HY, Bode NM, Kurgan GL, Detweiler AM, Vakulskas CA, Neff NF, Sheikali A, Menezes ST, Chrobok J, Hernández González EM, Majeti R, Notarangelo LD, Porteus MH. Pavel-Dinu M, et al. Among authors: detweiler am. Blood Adv. 2024 Apr 9;8(7):1820-1833. doi: 10.1182/bloodadvances.2023011766. Blood Adv. 2024. PMID: 38096800 Free PMC article.
Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes.
Dos Santos T, Dai XQ, Jones RC, Spigelman AF, Mummey HM, Ewald JD, Ellis CE, Lyon JG, Smith N, Bautista A, Manning Fox JE, Neff NF, Detweiler AM, Tan M, Arrojo E Drigo R, Xia J, Camunas-Soler J, Gaulton KJ, Quake SR, MacDonald PE. Dos Santos T, et al. Among authors: detweiler am. J Clin Invest. 2025 Sep 30:e195267. doi: 10.1172/JCI195267. Online ahead of print. J Clin Invest. 2025. PMID: 41026524 Free article.
43 results