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45 results

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Page 1
The chromatin accessibility landscape of primary human cancers.
Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, Felau I, Castro MAA, Berman BP, Staudt LM, Zenklusen JC, Laird PW, Curtis C; Cancer Genome Atlas Analysis Network; Greenleaf WJ, Chang HY. Corces MR, et al. Science. 2018 Oct 26;362(6413):eaav1898. doi: 10.1126/science.aav1898. Science. 2018. PMID: 30361341 Free PMC article.
Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers.
Sundaram L, Kumar A, Zatzman M, Salcedo A, Ravindra N, Shams S, Louie BH, Bagdatli ST, Myers MA, Sarmashghi S, Choi HY, Choi WY, Yost KE, Zhao Y, Granja JM, Hinoue T, Hayes DN, Cherniack A, Felau I, Choudhry H, Zenklusen JC, Farh KK, McPherson A, Curtis C, Laird PW; Cancer Genome Atlas Analysis Network‡; Demchok JA, Yang L, Tarnuzzer R, Caesar-Johnson SJ, Wang Z, Doane AS, Khurana E, Castro MAA, Lazar AJ, Broom BM, Weinstein JN, Akbani R, Kumar SV, Raphael BJ, Wong CK, Stuart JM, Safavi R, Benz CC, Johnson BK, Kyi C, Shen H, Corces MR, Chang HY, Greenleaf WJ. Sundaram L, et al. Among authors: doane as. Science. 2024 Sep 6;385(6713):eadk9217. doi: 10.1126/science.adk9217. Epub 2024 Sep 6. Science. 2024. PMID: 39236169 Free PMC article.
IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer.
Amisaki M, Zebboudj A, Yano H, Zhang SL, Payne G, Chandra AK, Yu R, Guasp P, Sethna ZM, Ohmoto A, Rojas LA, Cheng C, Waters T, Solovyov A, Martis S, Doane AS, Reiche C, Bruno EM, Milighetti M, Soares K, Odgerel Z, Moral JA, Zhao JN, Gönen M, Gardner R, Tumanov AV, Khan AG, Vergnolle O, Nyakatura EK, Lorenz IC, Baca M, Patterson E, Greenbaum B, Artis D, Merghoub T, Balachandran VP. Amisaki M, et al. Among authors: doane as. Nature. 2025 Feb;638(8052):1076-1084. doi: 10.1038/s41586-024-08426-5. Epub 2025 Jan 15. Nature. 2025. PMID: 39814891 Free PMC article.
BTG1 mutation yields supercompetitive B cells primed for malignant transformation.
Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic D, Papin A, Hoehn KB, Kots E, Ersching J, Bandyopadhyay A, Barin E, Poh HX, Evans CM, Chadburn A, Chen Z, Shen H, Isles HM, Pelzer B, Tsialta I, Doane AS, Geng H, Rehman MH, Melnick J, Morgan W, Nguyen DTT, Elemento O, Kharas MG, Jaffrey SR, Scott DW, Khelashvili G, Meyer-Hermann M, Victora GD, Melnick A. Mlynarczyk C, et al. Among authors: doane as. Science. 2023 Jan 20;379(6629):eabj7412. doi: 10.1126/science.abj7412. Epub 2023 Jan 20. Science. 2023. PMID: 36656933 Free PMC article.
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Yusufova N, Kloetgen A, Teater M, Osunsade A, Camarillo JM, Chin CR, Doane AS, Venters BJ, Portillo-Ledesma S, Conway J, Phillip JM, Elemento O, Scott DW, Béguelin W, Licht JD, Kelleher NL, Staudt LM, Skoultchi AI, Keogh MC, Apostolou E, Mason CE, Imielinski M, Schlick T, David Y, Tsirigos A, Allis CD, Soshnev AA, Cesarman E, Melnick AM. Yusufova N, et al. Among authors: doane as. Nature. 2021 Jan;589(7841):299-305. doi: 10.1038/s41586-020-3017-y. Epub 2020 Dec 9. Nature. 2021. PMID: 33299181 Free PMC article.
A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation.
Drozdz MM, Doane AS, Alkallas R, Desman G, Bareja R, Reilly M, Bang J, Yusupova M, You J, Eraslan Z, Wang JZ, Verma A, Aguirre K, Kane E, Watson IR, Elemento O, Piskounova E, Merghoub T, Zippin JH. Drozdz MM, et al. Among authors: doane as. Cell Rep. 2022 Sep 27;40(13):111412. doi: 10.1016/j.celrep.2022.111412. Cell Rep. 2022. PMID: 36170819 Free PMC article.
Three-dimensional genome landscape of primary human cancers.
Yost KE, Zhao Y, Hung KL, Zhu K, Xu D, Corces MR, Shams S, Louie BH, Sarmashghi S, Sundaram L, Luebeck J, Clarke S, Doane AS, Granja JM, Choudhry H, Imieliński M, Cherniack AD, Khurana E, Bafna V, Felau I, Zenklusen JC, Laird PW, Curtis C; Cancer Genome Atlas Analysis Network; Greenleaf WJ, Chang HY. Yost KE, et al. Among authors: doane as. Nat Genet. 2025 May;57(5):1189-1200. doi: 10.1038/s41588-025-02188-0. Epub 2025 May 12. Nat Genet. 2025. PMID: 40355593 Free PMC article.
Regulatory elements in molecular networks.
Doane AS, Elemento O. Doane AS, et al. Wiley Interdiscip Rev Syst Biol Med. 2017 May;9(3):10.1002/wsbm.1374. doi: 10.1002/wsbm.1374. Epub 2017 Jan 17. Wiley Interdiscip Rev Syst Biol Med. 2017. PMID: 28093886 Free PMC article. Review.
Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors.
Mosquera MJ, Kim S, Bareja R, Fang Z, Cai S, Pan H, Asad M, Martin ML, Sigouros M, Rowdo FM, Ackermann S, Capuano J, Bernheim J, Cheung C, Doane A, Brady N, Singh R, Rickman DS, Prabhu V, Allen JE, Puca L, Coskun AF, Rubin MA, Beltran H, Mosquera JM, Elemento O, Singh A. Mosquera MJ, et al. Among authors: doane a. Adv Mater. 2022 Jan;34(2):e2100096. doi: 10.1002/adma.202100096. Epub 2021 Nov 14. Adv Mater. 2022. PMID: 34676924 Free PMC article.
Prevalence of astroviruses in a children's hospital.
Shastri S, Doane AM, Gonzales J, Upadhyayula U, Bass DM. Shastri S, et al. Among authors: doane am. J Clin Microbiol. 1998 Sep;36(9):2571-4. doi: 10.1128/JCM.36.9.2571-2574.1998. J Clin Microbiol. 1998. PMID: 9705394 Free PMC article.
45 results