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Page 1
Pharmacokinetics and pharmacodynamics of clofazimine in a mouse model of tuberculosis.
Swanson RV, Adamson J, Moodley C, Ngcobo B, Ammerman NC, Dorasamy A, Moodley S, Mgaga Z, Tapley A, Bester LA, Singh S, Grosset JH, Almeida DV. Swanson RV, et al. Among authors: dorasamy a. Antimicrob Agents Chemother. 2015;59(6):3042-51. doi: 10.1128/AAC.00260-15. Epub 2015 Mar 9. Antimicrob Agents Chemother. 2015. PMID: 25753644 Free PMC article.
A 3-month clofazimine-rifapentine-containing regimen for drug-susceptible tuberculosis versus standard of care (Clo-Fast): a randomised, open-label, phase 2c clinical trial.
Metcalfe JZ, Weir IR, Scarsi KK, Mendoza-Ticona A, Pierre S, Hall L, Leon-Cruz J, Svensson EM, Koele SE, Samaneka W, Kanyama C, Yohane M, Nevrekar N, Ntsalaze B, Marc JB, Goth M, Maartens G, Chaisson R; ACTG A5362 study team. Metcalfe JZ, et al. Lancet Infect Dis. 2026 Jan;26(1):46-54. doi: 10.1016/S1473-3099(25)00436-0. Epub 2025 Sep 4. Lancet Infect Dis. 2026. PMID: 40915311 Free article. Clinical Trial.
Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy.
Swanson RV, Ammerman NC, Ngcobo B, Adamson J, Moodley C, Dorasamy A, Moodley S, Mgaga Z, Bester LA, Singh SD, Almeida DV, Grosset JH. Swanson RV, et al. Among authors: dorasamy a. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2864-9. doi: 10.1128/AAC.00177-16. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26926638 Free PMC article.
Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules.
Pan SJ, Tapley A, Adamson J, Little T, Urbanowski M, Cohen K, Pym A, Almeida D, Dorasamy A, Layre E, Young DC, Singh R, Patel VB, Wallengren K, Ndung'u T, Wilson D, Moody DB, Bishai W. Pan SJ, et al. Among authors: dorasamy a. J Infect Dis. 2015 Dec 1;212(11):1827-34. doi: 10.1093/infdis/jiv312. Epub 2015 May 26. J Infect Dis. 2015. PMID: 26014799 Free PMC article.
Direct Susceptibility Testing of Mycobacterium tuberculosis for Pyrazinamide by Use of the Bactec MGIT 960 System.
Demers AM, Venter A, Friedrich SO, Rojas-Ponce G, Mapamba D, Jugheli L, Sasamalo M, Almeida D, Dorasamy A, Jentsch U, Gibson M, Everitt D, Eisenach KD, Diacon AH. Demers AM, et al. Among authors: dorasamy a. J Clin Microbiol. 2016 May;54(5):1276-81. doi: 10.1128/JCM.03162-15. Epub 2016 Feb 24. J Clin Microbiol. 2016. PMID: 26912751 Free PMC article. Clinical Trial.