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Year Number of Results
1986 1
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2001 4
2002 2
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2005 2
2006 8
2007 16
2008 20
2009 20
2010 24
2011 19
2012 28
2013 23
2014 32
2015 25
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1,114 results

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Page 1
SenNet recommendations for detecting senescent cells in different tissues.
Suryadevara V, Hudgins AD, Rajesh A, Pappalardo A, Karpova A, Dey AK, Hertzel A, Agudelo A, Rocha A, Soygur B, Schilling B, Carver CM, Aguayo-Mazzucato C, Baker DJ, Bernlohr DA, Jurk D, Mangarova DB, Quardokus EM, Enninga EAL, Schmidt EL, Chen F, Duncan FE, Cambuli F, Kaur G, Kuchel GA, Lee G, Daldrup-Link HE, Martini H, Phatnani H, Al-Naggar IM, Rahman I, Nie J, Passos JF, Silverstein JC, Campisi J, Wang J, Iwasaki K, Barbosa K, Metis K, Nernekli K, Niedernhofer LJ, Ding L, Wang L, Adams LC, Ruiyang L, Doolittle ML, Teneche MG, Schafer MJ, Xu M, Hajipour M, Boroumand M, Basisty N, Sloan N, Slavov N, Kuksenko O, Robson P, Gomez PT, Vasilikos P, Adams PD, Carapeto P, Zhu Q, Ramasamy R, Perez-Lorenzo R, Fan R, Dong R, Montgomery RR, Shaikh S, Vickovic S, Yin S, Kang S, Suvakov S, Khosla S, Garovic VD, Menon V, Xu Y, Song Y, Suh Y, Dou Z, Neretti N. Suryadevara V, et al. Among authors: dou z. Nat Rev Mol Cell Biol. 2024 Dec;25(12):1001-1023. doi: 10.1038/s41580-024-00738-8. Epub 2024 Jun 3. Nat Rev Mol Cell Biol. 2024. PMID: 38831121 Review.
Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Dou Z, et al. Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4. Nature. 2017. PMID: 28976970 Free PMC article.
SIRT1 is downregulated by autophagy in senescence and ageing.
Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, Lu C, Nicastri M, Bretz C, Winkler JD, Amaravadi R, Garcia BA, Adams PD, Ott M, Tong W, Johansen T, Dou Z, Berger SL. Xu C, et al. Among authors: dou z. Nat Cell Biol. 2020 Oct;22(10):1170-1179. doi: 10.1038/s41556-020-00579-5. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989246 Free PMC article.
WSTF nuclear autophagy regulates chronic but not acute inflammation.
Wang Y, Eapen VV, Liang Y, Kournoutis A, Sherman MS, Xu Y, Onorati A, Li X, Zhou X, Corey KE, Du K, Cabral Burkard AM, Ho CK, Xie J, Zhang H, Maeso-Díaz R, Ma X, Rieprecht U, O'Brien T, Cetinbas M, Wang L, Liu J, Bretz C, Havas AP, Zhou Z, Ho Sui SJ, Saladi SV, Sadreyev RI, Adams PD, Kingston RE, Diehl AM, Alman B, Goessling W, Yue Z, Wang XF, Johansen T, Dou Z. Wang Y, et al. Among authors: dou z. Nature. 2025 Aug;644(8077):780-789. doi: 10.1038/s41586-025-09234-1. Epub 2025 Jul 2. Nature. 2025. PMID: 40604282
Loss of epigenetic information as a cause of mammalian aging.
Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O'Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA. Yang JH, et al. Among authors: dou z. Cell. 2024 Feb 29;187(5):1312-1313. doi: 10.1016/j.cell.2024.01.049. Cell. 2024. PMID: 38428398 Free article. No abstract available.
CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms.
Zhou X, Wang Y, Dou Z, Delfanti G, Tsahouridis O, Pellegry CM, Zingarelli M, Atassi G, Woodcock MG, Casorati G, Dellabona P, Kim WY, Guo L, Savoldo B, Tsagaratou A, Milner JJ, Metelitsa LS, Dotti G. Zhou X, et al. Among authors: dou z. Nat Cancer. 2024 Nov;5(11):1607-1621. doi: 10.1038/s43018-024-00830-0. Epub 2024 Oct 1. Nat Cancer. 2024. PMID: 39354225 Free PMC article.
p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells.
Miller KN, Li B, Pierce-Hoffman HR, Patel S, Lei X, Rajesh A, Teneche MG, Havas AP, Gandhi A, Macip CC, Lyu J, Victorelli SG, Woo SH, Lagnado AB, LaPorta MA, Liu T, Dasgupta N, Li S, Davis A, Korotkov A, Hultenius E, Gao Z, Altman Y, Porritt RA, Garcia G, Mogler C, Seluanov A, Gorbunova V, Kaech SM, Tian X, Dou Z, Chen C, Passos JF, Adams PD. Miller KN, et al. Among authors: dou z. Nat Commun. 2025 Mar 5;16(1):2229. doi: 10.1038/s41467-025-57229-3. Nat Commun. 2025. PMID: 40044657 Free PMC article.
Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming.
Zhao T, He L, Wong LP, Mei S, Xia J, Xu Y, Van Vranken JG, Mazzola M, Chen L, Rhee C, Fang T, Fukushima T, Sayles LC, Diaz M, Gibbons JAB, Mostoslavsky R, Gygi SP, Dou Z, Sykes DB, Sadreyev RI, Sweet-Cordero EA, Scadden DT. Zhao T, et al. Among authors: dou z. Cell Metab. 2025 Aug 5;37(8):1667-1681.e13. doi: 10.1016/j.cmet.2025.05.009. Epub 2025 Jun 11. Cell Metab. 2025. PMID: 40505660
1,114 results