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84 results

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Page 1
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Voysey M, Clemens SAC, Madhi SA, Weckx LY, Folegatti PM, Aley PK, Angus B, Baillie VL, Barnabas SL, Bhorat QE, Bibi S, Briner C, Cicconi P, Collins AM, Colin-Jones R, Cutland CL, Darton TC, Dheda K, Duncan CJA, Emary KRW, Ewer KJ, Fairlie L, Faust SN, Feng S, Ferreira DM, Finn A, Goodman AL, Green CM, Green CA, Heath PT, Hill C, Hill H, Hirsch I, Hodgson SHC, Izu A, Jackson S, Jenkin D, Joe CCD, Kerridge S, Koen A, Kwatra G, Lazarus R, Lawrie AM, Lelliott A, Libri V, Lillie PJ, Mallory R, Mendes AVA, Milan EP, Minassian AM, McGregor A, Morrison H, Mujadidi YF, Nana A, O'Reilly PJ, Padayachee SD, Pittella A, Plested E, Pollock KM, Ramasamy MN, Rhead S, Schwarzbold AV, Singh N, Smith A, Song R, Snape MD, Sprinz E, Sutherland RK, Tarrant R, Thomson EC, Török ME, Toshner M, Turner DPJ, Vekemans J, Villafana TL, Watson MEE, Williams CJ, Douglas AD, Hill AVS, Lambe T, Gilbert SC, Pollard AJ; Oxford COVID Vaccine Trial Group. Voysey M, et al. Among authors: douglas ad. Lancet. 2021 Jan 9;397(10269):99-111. doi: 10.1016/S0140-6736(20)32661-1. Epub 2020 Dec 8. Lancet. 2021. PMID: 33306989 Free PMC article. Clinical Trial.
Rapid-response manufacturing of adenovirus-vectored vaccines.
Joe CCD, Chopra N, Nestola P, Niemann J, Douglas AD. Joe CCD, et al. Among authors: douglas ad. Nat Biotechnol. 2023 Mar;41(3):314-316. doi: 10.1038/s41587-023-01682-2. Nat Biotechnol. 2023. PMID: 36890199 No abstract available.
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial.
Folegatti PM, Ewer KJ, Aley PK, Angus B, Becker S, Belij-Rammerstorfer S, Bellamy D, Bibi S, Bittaye M, Clutterbuck EA, Dold C, Faust SN, Finn A, Flaxman AL, Hallis B, Heath P, Jenkin D, Lazarus R, Makinson R, Minassian AM, Pollock KM, Ramasamy M, Robinson H, Snape M, Tarrant R, Voysey M, Green C, Douglas AD, Hill AVS, Lambe T, Gilbert SC, Pollard AJ; Oxford COVID Vaccine Trial Group. Folegatti PM, et al. Among authors: douglas ad. Lancet. 2020 Aug 15;396(10249):467-478. doi: 10.1016/S0140-6736(20)31604-4. Epub 2020 Jul 20. Lancet. 2020. PMID: 32702298 Free PMC article. Clinical Trial.
Rabies glycoprotein engineering for improved stability and expression.
English S, Fedosyuk S, Orliacq F, Tem V, Taylor W, Alam N, Xiang ZQ, Thorley L, López-Camacho C, Ertl HC, Douglas AD. English S, et al. Among authors: douglas ad. Vaccine. 2025 Aug 30;62:127541. doi: 10.1016/j.vaccine.2025.127541. Epub 2025 Jul 26. Vaccine. 2025. PMID: 40716142 Free PMC article.
Damage control thoracotomy trends, techniques, and outcomes: An EAST multicenter trial.
Douglas AD, Puzio T, Murphy P, Nahmias J, Bugaev N, Kaafarani H, Tatebe L, Robinson B, Carrick M, Finch J, Smith H, Hoefer L, Keskey R, Snyder A, LeClair MJ, Turay D, Wang G, Capron G, Cheung D, Valgardsson A, Bankhead B, Liveris A, Taylor J, Cromer D, Goldenberg-Sandau A, Powers T, Ratnasekera A, Seng S, Figueroa J, Mulita F, Panagiotopoulos I, Ramos J, Villalobos L, Frederick N, Favors L, Maxwell R, Spalding C, Kurian A, Sperwer K, Senekijan L, Gebran A, Burke R, Dalavayi S, Hoshal G, Cocanour C, Chang G, Meagher A. Douglas AD, et al. J Trauma Acute Care Surg. 2025 Sep 1;99(3):460-467. doi: 10.1097/TA.0000000000004492. Epub 2025 May 28. J Trauma Acute Care Surg. 2025. PMID: 40435348
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex.
Williams BG, King LDW, Pulido D, Quinkert D, Lias AM, Silk SE, Ragotte RJ, Davies H, Barrett JR, McHugh K, Rigby CA, Alanine DGW, Barfod L, Shea MW, Cowley LA, Dabbs RA, Pattinson DJ, Douglas AD, Lyth OR, Illingworth JJ, Jin J, Carnrot C, Kotraiah V, Christen JM, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Skinner K, Miura K, Long CA, Higgins MK, Draper SJ. Williams BG, et al. Among authors: douglas ad. Nat Commun. 2024 Jun 7;15(1):4857. doi: 10.1038/s41467-024-48721-3. Nat Commun. 2024. PMID: 38849365 Free PMC article.
Manufacturing a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine to meet global needs.
Joe CCD, Jiang J, Linke T, Li Y, Fedosyuk S, Gupta G, Berg A, Segireddy RR, Mainwaring D, Joshi A, Cashen P, Rees B, Chopra N, Nestola P, Humphreys J, Davies S, Smith N, Bruce S, Verbart D, Bormans D, Knevelman C, Woodyer M, Davies L, Cooper L, Kapanidou M, Bleckwenn N, Pappas D, Lambe T, Smith DC, Green CM, Venkat R, Ritchie AJ, Gilbert SC, Turner R, Douglas AD. Joe CCD, et al. Among authors: douglas ad. Biotechnol Bioeng. 2022 Jan;119(1):48-58. doi: 10.1002/bit.27945. Epub 2021 Nov 15. Biotechnol Bioeng. 2022. PMID: 34585736 Free PMC article.
84 results