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Page 1
Subcutaneous Administration of a Monoclonal Antibody to Prevent Malaria.
Kayentao K, Ongoiba A, Preston AC, Healy SA, Hu Z, Skinner J, Doumbo S, Wang J, Cisse H, Doumtabe D, Traore A, Traore H, Djiguiba A, Li S, Peterson ME, Telscher S, Idris AH, Adams WC, McDermott AB, Narpala S, Lin BC, Serebryannyy L, Hickman SP, McDougal AJ, Vazquez S, Reiber M, Stein JA, Gall JG, Carlton K, Schwabl P, Traore S, Keita M, Zéguimé A, Ouattara A, Doucoure M, Dolo A, Murphy SC, Neafsey DE, Portugal S, Djimdé A, Traore B, Seder RA, Crompton PD; Mali Malaria mAb Trial Team. Kayentao K, et al. Among authors: doumbo s. N Engl J Med. 2024 May 2;390(17):1549-1559. doi: 10.1056/NEJMoa2312775. Epub 2024 Apr 26. N Engl J Med. 2024. PMID: 38669354 Free PMC article. Clinical Trial.
Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein.
Dacon C, Moskovitz R, Swearingen K, Da Silva Pereira L, Flores-Garcia Y, Aleshnick M, Kanatani S, Flynn B, Molina-Cruz A, Wollenberg K, Traver M, Kirtley P, Purser L, Dillon M, Bonilla B, Franco A, Petros S, Kritzberg J, Tucker C, Paez GG, Gupta P, Shears MJ, Pazzi J, Edgar JM, Teng AA, Belmonte A, Oda K, Doumbo S, Krymskaya L, Skinner J, Li S, Ghosal S, Kayentao K, Ongoiba A, Vaughan A, Campo JJ, Traore B, Barillas-Mury C, Wijayalath W, Idris A, Crompton PD, Sinnis P, Wilder BK, Zavala F, Seder RA, Wilson IA, Tan J. Dacon C, et al. Among authors: doumbo s. Science. 2025 Jan 3;387(6729):eadr0510. doi: 10.1126/science.adr0510. Epub 2025 Jan 3. Science. 2025. PMID: 39745947 Free PMC article.
Safety and Efficacy of a Monoclonal Antibody against Malaria in Mali.
Kayentao K, Ongoiba A, Preston AC, Healy SA, Doumbo S, Doumtabe D, Traore A, Traore H, Djiguiba A, Li S, Peterson ME, Telscher S, Idris AH, Kisalu NK, Carlton K, Serebryannyy L, Narpala S, McDermott AB, Gaudinski M, Traore S, Cisse H, Keita M, Skinner J, Hu Z, Zéguimé A, Ouattara A, Doucoure M, Dolo A, Djimdé A, Traore B, Seder RA, Crompton PD; Mali Malaria mAb Trial Team. Kayentao K, et al. Among authors: doumbo s. N Engl J Med. 2022 Nov 17;387(20):1833-1842. doi: 10.1056/NEJMoa2206966. Epub 2022 Oct 31. N Engl J Med. 2022. PMID: 36317783 Free PMC article. Clinical Trial.
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Wang LT, Cooper AJR, Farrell B, Miura K, Diouf A, Müller-Sienerth N, Crosnier C, Purser L, Kirtley PJ, Maciuszek M, Barrett JR, McHugh K, Ogwang R, Tucker C, Li S, Doumbo S, Doumtabe D, Pyo CW, Skinner J, Nielsen CM, Silk SE, Kayentao K, Ongoiba A, Zhao M, Nguyen DC, Lee FE, Minassian AM, Geraghty DE, Traore B, Seder RA, Wilder BK, Crompton PD, Wright GJ, Long CA, Draper SJ, Higgins MK, Tan J. Wang LT, et al. Among authors: doumbo s. Cell. 2024 Sep 5;187(18):4981-4995.e14. doi: 10.1016/j.cell.2024.06.037. Epub 2024 Jul 25. Cell. 2024. PMID: 39059381 Free PMC article.
Autoantibodies inhibit Plasmodium falciparum growth and are associated with protection from clinical malaria.
Hagadorn KA, Peterson ME, Kole H, Scott B, Skinner J, Diouf A, Takashima E, Ongoiba A, Doumbo S, Doumtabe D, Li S, Sekar P, Yan M, Zhu C, Nagaoka H, Kanoi BN, Li QZ, Long C, Long EO, Kayentao K, Jenks SA, Sanz I, Tsuboi T, Traore B, Bolland S, Miura K, Crompton PD, Hopp CS. Hagadorn KA, et al. Among authors: doumbo s. Immunity. 2024 Aug 13;57(8):1769-1779.e4. doi: 10.1016/j.immuni.2024.05.024. Epub 2024 Jun 19. Immunity. 2024. PMID: 38901428 Free PMC article.
Infection length and host environment influence on Plasmodium falciparum dry season reservoir.
Andrade CM, Carrasquilla M, Dabbas U, Briggs J, van Dijk H, Sergeev N, Sissoko A, Niangaly M, Ntalla C, LaVerriere E, Skinner J, Golob K, Richter J, Cisse H, Li S, Hendry JA, Asghar M, Doumtabe D, Farnert A, Ruppert T, Neafsey DE, Kayentao K, Doumbo S, Ongoiba A, Crompton PD, Traore B, Greenhouse B, Portugal S. Andrade CM, et al. Among authors: doumbo s. EMBO Mol Med. 2024 Oct;16(10):2349-2375. doi: 10.1038/s44321-024-00127-w. Epub 2024 Sep 16. EMBO Mol Med. 2024. PMID: 39284949 Free PMC article.
The estimated burden of fungal diseases in Mali.
Doumbo SN, Cissoko Y, Dama S, Niangaly A, Garango A, Konaté A, Koné A, Traoré B, Thera M, Djimde A, Denning DW. Doumbo SN, et al. J Mycol Med. 2023 Mar;33(1):101333. doi: 10.1016/j.mycmed.2022.101333. Epub 2022 Sep 22. J Mycol Med. 2023. PMID: 36270216 Review.
Anti-sporozoite monoclonal antibody for malaria prevention: secondary efficacy outcome of a phase 2 randomized trial.
Skinner J, Kayentao K, Ongoiba A, Healy SA, Hu Z, Preston AC, Niangaly A, Schwabl P, Cisse H, Doumbo S, Doumtabe D, Traore A, Li S, Peterson ME, Seilie AM, Chavtur C, Staubus W, Chang M, Kelley K, Traore H, Djiguiba A, Keita M, Ouattara A, Doucoure M, Keita M, Diarra D, Sylla M, Diakite D, Konate M, Traore S, Zéguimé A, Dolo A, Neafsey DE, Murphy SC, Traore B, Seder RA, Crompton PD. Skinner J, et al. Among authors: doumbo s. Nat Med. 2025 Aug;31(8):2682-2690. doi: 10.1038/s41591-025-03739-y. Epub 2025 Jun 3. Nat Med. 2025. PMID: 40461818 Free PMC article. Clinical Trial.
65 results