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Page 1
Showing results for eglin c
Search for Eglan C instead (1 results)
Protective efficacy of Eglin C from Hirudo medicinalis against Eimeria papillata-induced coccidiosis.
Al-Sayed SE, Abdel-Latif M, Abdel-Haleem HM, El-Shahawy G, Abdel-Tawab H. Al-Sayed SE, et al. Vet Parasitol. 2023 Feb;314:109869. doi: 10.1016/j.vetpar.2022.109869. Epub 2022 Dec 24. Vet Parasitol. 2023. PMID: 36586192
The fractions reveled only a protein at 8 kDa while the results of spectroscopy and bioinformatics identified the protein as Eglin C. The pooled fractions containing Eglin C were tested in vitro to determine its stimulation for the intestinal lymphocyt …
The fractions reveled only a protein at 8 kDa while the results of spectroscopy and bioinformatics identified the protein as Eglin …
A brief review of the biochemistry and pharmacology of Eglin c, an elastase inhibitor.
Braun NJ, Schnebli HP. Braun NJ, et al. Eur J Respir Dis Suppl. 1986;146:541-7. Eur J Respir Dis Suppl. 1986. PMID: 3536558 Review.
Eglin c is a small protein inhibitor of human leucocyte elastase and cathepsin G which has potential as a therapeutic agent for the treatment of disease states associated with inflammation. In particular, Eglin c has been proven effective in experiment …
Eglin c is a small protein inhibitor of human leucocyte elastase and cathepsin G which has potential as a therapeutic agent fo …
Engineered eglin c variants inhibit yeast and human proprotein processing proteases, Kex2 and furin.
Komiyama T, Fuller RS. Komiyama T, et al. Biochemistry. 2000 Dec 12;39(49):15156-65. doi: 10.1021/bi001907c. Biochemistry. 2000. PMID: 11106495
We engineered eglin c, a potent subtilisin inhibitor, to create inhibitors for enzymes of the Kex2/furin family of proprotein processing proteases. ...
We engineered eglin c, a potent subtilisin inhibitor, to create inhibitors for enzymes of the Kex2/furin family of proprotein …
Eglin-c prevents monocrotaline-induced ventilatory dysfunction.
Lai YL, Zhou KR. Lai YL, et al. J Appl Physiol (1985). 1997 Jan;82(1):324-8. doi: 10.1152/jappl.1997.82.1.324. J Appl Physiol (1985). 1997. PMID: 9029233 Free article.
To accomplish this, we used an elastase inhibitor eglin-c to suppress the activity of endogenous elastase. Thirty-five young Sprague-Dawley rats were randomly divided into six groups: control, MCT, eglin-c(1), eglin-c(2), eglin- …
To accomplish this, we used an elastase inhibitor eglin-c to suppress the activity of endogenous elastase. Thirty-five young S …
Inhibition of porcine pancreatic elastase-induced emphysema by eglin-c.
Lai YL, Diamond L. Lai YL, et al. Exp Lung Res. 1990 Sep-Oct;16(5):547-57. doi: 10.3109/01902149009068826. Exp Lung Res. 1990. PMID: 2226359 Free article.
However, no significant alterations in quasi-static compliance, TLC, or MLI were found in animals treated with PPE and eglin-c. Three additional groups were used to examine the effects of intratracheal instillation of saline or eglin-c: control (n = 9) …
However, no significant alterations in quasi-static compliance, TLC, or MLI were found in animals treated with PPE and eglin-c …
Effect of varying the time interval between intratracheal administration of eglin-c and human neutrophil elastase on prevention of emphysema and secretory cell metaplasia in hamsters. With observations on the fate of eglin-c and the effect of repeated instillations.
Lucey EC, Stone PJ, Christensen TG, Breuer R, Calore JD, Snider GL. Lucey EC, et al. Am Rev Respir Dis. 1986 Sep;134(3):471-5. doi: 10.1164/arrd.1986.134.3.471. Am Rev Respir Dis. 1986. PMID: 3530070
Eglin-c is a naturally occurring polypeptide of 70 amino acids with a molecular mass of 8,100 daltons. ...The clearance of [3H]eglin-c from the lungs was assessed. Four h after intratracheal instillation of 446 micrograms of [3H]eglin-c, …
Eglin-c is a naturally occurring polypeptide of 70 amino acids with a molecular mass of 8,100 daltons. ...The clearance of [3H …
Interference of recombinant eglin C, a proteinase inhibitor extracted from leeches, with neutrophil-mediated platelet activation.
Renesto P, Ferrer-Lopez P, Chignard M. Renesto P, et al. Lab Invest. 1990 Apr;62(4):409-16. Lab Invest. 1990. PMID: 2159081
Inhibition was specific (a 100 times higher concentration of eglin C did not alter platelet activation induced by thrombin), and surmountable (an increase of cathepsin G concentration reduced the eglin C effect). Thus, the mechanism of inhibition by …
Inhibition was specific (a 100 times higher concentration of eglin C did not alter platelet activation induced by thrombin), a …
Eglin-c, a polypeptide derived from the medicinal leech, prevents human neutrophil elastase-induced emphysema and bronchial secretory cell metaplasia in the hamster.
Snider GL, Stone PJ, Lucey EC, Breuer R, Calore JD, Seshadri T, Catanese A, Maschler R, Schnebli HP. Snider GL, et al. Am Rev Respir Dis. 1985 Dec;132(6):1155-61. doi: 10.1164/arrd.1985.132.6.1155. Am Rev Respir Dis. 1985. PMID: 3907441
Eglin-c (Eg-c), a polypeptide with a molecular mass of 8,100 daltons, was purified from the medicinal leech Hirudo medicinalis. ...
Eglin-c (Eg-c), a polypeptide with a molecular mass of 8,100 daltons, was purified from the medicinal leech Hirudo medicinalis …
289 results