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A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses.
Van Loy B, Pujol E, Kamata K, Lee XY, Bakirtzoglou N, Van Berwaer R, Vandeput J, Mestdagh C, Persoons L, De Wijngaert B, Goovaerts Q, Noppen S, Jacquemyn M, Ahmadzadeh K, Bernaerts E, Martín-López J, Escriche C, Vanmechelen B, Krasniqi B, Singh AK, Daelemans D, Maes P, Matthys P, Dehaen W, Rozenski J, Das K, Voet A, Vázquez S, Naesens L, Stevaert A. Van Loy B, et al. Among authors: escriche c. PLoS Pathog. 2025 Feb 11;21(2):e1012571. doi: 10.1371/journal.ppat.1012571. eCollection 2025 Feb. PLoS Pathog. 2025. PMID: 39932973 Free PMC article.
Influence of the Covid-19 pandemic on out-of-hospital cardiac arrest. A Spanish nationwide prospective cohort study.
Rosell Ortiz F, Fernández Del Valle P, Knox EC, Jiménez Fábrega X, Navalpotro Pascual JM, Mateo Rodríguez I, Ruiz Azpiazu JI, Iglesias Vázquez JA, Echarri Sucunza A, Alonso Moreno DF, Forner Canos AB, García-Ochoa Blanco MJ, López Cabeza N, Mainar Gómez B, Batres Gómez S, Cortés Ramas JA, Ceniceros Rozalén MI, Guirao Salas FA, Fernández Martínez B, Daponte Codina A; OHSCAR investigators. Rosell Ortiz F, et al. Resuscitation. 2020 Dec;157:230-240. doi: 10.1016/j.resuscitation.2020.09.037. Epub 2020 Oct 10. Resuscitation. 2020. PMID: 33049385 Free PMC article.
N-[(Thiophen-3-yl)methyl]benzamides as Fusion Inhibitors of Influenza Virus Targeting H1 and H5 Hemagglutinins.
Rimaux S, Valdivia A, Martín-López J, Francesconi V, Escriche C, Mestdagh C, Van Berwaer R, Schurmans L, Verleye K, Noppen S, Lozano Ó, Stevaert A, Luque FJ, Naesens L, Vázquez S. Rimaux S, et al. Among authors: escriche c. J Med Chem. 2025 Sep 11;68(17):18491-18518. doi: 10.1021/acs.jmedchem.5c01357. Epub 2025 Aug 29. J Med Chem. 2025. PMID: 40880513 Free PMC article.
Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain.
Codony S, Jora B, Santos-Caballero M, Qiu Q, Calvó-Tusell C, Escriche C, Turcu AL, Prischi F, Bartra C, Val C, Morisseau C, Pérez B, Bertran-Mostazo A, Osuna S, Corpas R, Griñán-Ferré C, Galdeano C, Loza MI, Pallàs M, Sanfeliu C, Hammock BD, Brea J, Feixas F, Conte MR, Cobos EJ, Vázquez S. Codony S, et al. Among authors: escriche c. J Enzyme Inhib Med Chem. 2025 Dec;40(1):2574990. doi: 10.1080/14756366.2025.2574990. Epub 2025 Oct 23. J Enzyme Inhib Med Chem. 2025. PMID: 41128518 Free PMC article.