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Page 1
Showing results for ester za
Search for Esther ZA instead (1 results)
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
van der Kant R, Langness VF, Herrera CM, Williams DA, Fong LK, Leestemaker Y, Steenvoorden E, Rynearson KD, Brouwers JF, Helms JB, Ovaa H, Giera M, Wagner SL, Bang AG, Goldstein LSB. van der Kant R, et al. Cell Stem Cell. 2019 Mar 7;24(3):363-375.e9. doi: 10.1016/j.stem.2018.12.013. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686764 Free PMC article.
Here, we perform a phenotypic screen for pTau accumulation in AD-patient iPSC-derived neurons and identify cholesteryl esters (CE), the storage product of excess cholesterol, as upstream regulators of Tau early during AD development. ...
Here, we perform a phenotypic screen for pTau accumulation in AD-patient iPSC-derived neurons and identify cholesteryl esters (CE), t …
1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains.
Jiang J, Zhao PL, Sigua LH, Chan A, Schönbrunn E, Qi J, Georg GI. Jiang J, et al. Arch Pharm (Weinheim). 2022 Nov;355(11):e2200288. doi: 10.1002/ardp.202200288. Epub 2022 Aug 8. Arch Pharm (Weinheim). 2022. PMID: 35941525 Free PMC article.
Based on a previously reported 1,4-dihydropyridinebutyrolactone virtual screening hit, nine lactone ring-opened ester and seven amide analogs were prepared. The analogs were designed to provide interactions with residues at the entrance of the ZA loop of the testis- …
Based on a previously reported 1,4-dihydropyridinebutyrolactone virtual screening hit, nine lactone ring-opened ester and seven amide …
Uremic Toxins and Vascular Dysfunction.
Six I, Flissi N, Lenglet G, Louvet L, Kamel S, Gallet M, Massy ZA, Liabeuf S. Six I, et al. Toxins (Basel). 2020 Jun 18;12(6):404. doi: 10.3390/toxins12060404. Toxins (Basel). 2020. PMID: 32570781 Free PMC article. Review.
[Research progress in tigliane-type macrocyclic diterpenoids].
Tan HH, Xia M, Su P, Huang LQ. Tan HH, et al. Zhongguo Zhong Yao Za Zhi. 2023 Sep;48(17):4620-4633. doi: 10.19540/j.cnki.cjcmm.20230427.201. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 37802801 Review. Chinese.
According to the different functional groups, they can be classified into types of phorbol esters, C-4 deoxyphorbol esters, C-12 deoxyphorbol esters, C-16 or C-17 substituted phorbol esters and others. ...
According to the different functional groups, they can be classified into types of phorbol esters, C-4 deoxyphorbol esters, C- …
[Research progress on rutin derivatives].
Mao YJ, Feng YL, Wang MJ, Lyu ZY, Zhai GY. Mao YJ, et al. Zhongguo Zhong Yao Za Zhi. 2021 Sep;46(18):4654-4665. doi: 10.19540/j.cnki.cjcmm.20210429.602. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34581073 Review. Chinese.
So far, a large number of rutin ethers, esters, and complexes have been synthesized and undergone activity testing. This paper reviews the structural modification of rutin in recent years, and the obtained derivatives have excellent properties and significant biological ac …
So far, a large number of rutin ethers, esters, and complexes have been synthesized and undergone activity testing. This paper review …
The Chemistry behind Chocolate Production.
Barišić V, Kopjar M, Jozinović A, Flanjak I, Ačkar Đ, Miličević B, Šubarić D, Jokić S, Babić J. Barišić V, et al. Molecules. 2019 Aug 30;24(17):3163. doi: 10.3390/molecules24173163. Molecules. 2019. PMID: 31480281 Free PMC article. Review.
Additionally, we present other components that may be naturally present or form during the production process, such as methylxanthines, aldehydes, esters, ketones, pyrazines, acids, and alcohols....
Additionally, we present other components that may be naturally present or form during the production process, such as methylxanthines, alde …
[Research progress on Polygalae Radix].
Liu L, Feng WH, Liu XQ, Liang YH, Li C, Wang ZM. Liu L, et al. Zhongguo Zhong Yao Za Zhi. 2021 Nov;46(22):5744-5759. doi: 10.19540/j.cnki.cjcmm.20210518.601. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34951162 Review. Chinese.
Modern research has revealed that Polygalae Radix mainly contains triterpenoid saponins, xanthone, oligosaccharide esters, etc., with the activities of improving memory, resisting dementia, protecting the brain, relieving cough, and removing phlegm, as well as sedation and …
Modern research has revealed that Polygalae Radix mainly contains triterpenoid saponins, xanthone, oligosaccharide esters, etc., with …
An antifouling model from the sea: a review of 25 years of zosteric acid studies.
Vilas-Boas C, Sousa E, Pinto M, Correia-da-Silva M. Vilas-Boas C, et al. Biofouling. 2017 Nov;33(10):927-942. doi: 10.1080/08927014.2017.1391951. Epub 2017 Nov 24. Biofouling. 2017. PMID: 29171304 Review.
ZA was shown to have appropriate environmental fate parameters such as high water solubility, a low log P, low bioaccumulation, and no ecotoxicity, which demonstrated the potential of ZA as a safe AF agent. This review also highlights that ZA has been success …
ZA was shown to have appropriate environmental fate parameters such as high water solubility, a low log P, low bioaccumulation, and n …
[Research progress on toxic effects and biomarkers of organophosphate ester flame retardant exposures].
Fu YZ, Shi YL, Lu XB, Tang S. Fu YZ, et al. Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Oct 6;54(10):1152-1160. doi: 10.3760/cma.j.cn112150-20200611-00868. Zhonghua Yu Fang Yi Xue Za Zhi. 2020. PMID: 33115204 Chinese.
Organophosphate ester (OPEs) has been widely used as a substitute of brominated biphenyl ethers and other brominated flame retardant (BFRs), and their health effects and environmental impacts are widely concerned. ...
Organophosphate ester (OPEs) has been widely used as a substitute of brominated biphenyl ethers and other brominated flame retardant …
[Process of gallnut suppository preparation].
Iminjan M, Cheng XM, Abudu N, Nurulla A, Ji ZH, Upur H. Iminjan M, et al. Zhongguo Zhong Yao Za Zhi. 2017 Aug;42(16):3136-3142. doi: 10.19540/j.cnki.cjcmm.20170705.001. Zhongguo Zhong Yao Za Zhi. 2017. PMID: 29171232 Chinese.
The main objective was to research the process of gallnut suppository preparation with its water extract as the main drug, and evaluate its irritation to rectal mucosa. gallnut extract was obtained by decocting method, and its suppository preparation was obtained by fusion method …
The main objective was to research the process of gallnut suppository preparation with its water extract as the main drug, and evaluate its …
899 results