The effect of IFNbeta-1b on the evolution of enhancing lesions in secondary progressive MS.
Brex PA, Molyneux PD, Smiddy P, Barkhof F, Filippi M, Yousry TA, Hahn D, Rolland Y, Salonen O, Pozzilli C, Polman CH, Thompson AJ, Kappos L, Miller DH; European Study Group on Interferon beta-1b in Secondary Progressive MS.
Brex PA, et al.
Neurology. 2001 Dec 26;57(12):2185-90. doi: 10.1212/wnl.57.12.2185.
Neurology. 2001.
PMID: 11756595
Clinical Trial.
METHODS: One hundred twenty-five patients with secondary progressive MS from seven European sites were randomized to receive either IFNbeta-1b or placebo. Monthly, contrast-enhanced T1-weighted MR images were acquired at baseline, at months 1 to 6, and at months 19 to 24. …
METHODS: One hundred twenty-five patients with secondary progressive MS from seven European sites were randomized to receive either I …