Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun;9(6):1286-9.
doi: 10.1039/c3mb70081j. Epub 2013 Apr 9.

Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus

Xiaoling Wang  1 , Jioji Tabudravu, Mostafa Ezzat Rateb, Krystal Joan Annand, Zhiwei Qin, Marcel Jaspars, Zixin Deng, Yi Yu, Hai Deng
Affiliations

Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus

Xiaoling Wang et al. Mol Biosyst. 2013 Jun.

Abstract

The gene cluster directing actinomycin G biosynthesis in Streptomyces iakyrus has been identified and sequenced. It contains one actinomycin synthetase I (ACMS I) gene and two copies of ACMS II and III genes. Genetic analysis demonstrates a unique partnership between the putative hydroxylation and chlorination activities as both acmG8 and acmG9 genes need to be transcribed for the biosynthesis of actinomycin G2-3, respectively.

PubMed Disclaimer

Publication types

Associated data

LinkOut - more resources