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Year Number of Results
1967 1
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2004 1
2005 1
2006 1
2007 1
2008 4
2010 3
2011 2
2012 1
2013 2
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2017 3
2019 3
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42 results

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Page 1
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.
Jansen J, Reimer KC, Nagai JS, Varghese FS, Overheul GJ, de Beer M, Roverts R, Daviran D, Fermin LAS, Willemsen B, Beukenboom M, Djudjaj S, von Stillfried S, van Eijk LE, Mastik M, Bulthuis M, Dunnen WD, van Goor H, Hillebrands JL, Triana SH, Alexandrov T, Timm MC, van den Berge BT, van den Broek M, Nlandu Q, Heijnert J, Bindels EMJ, Hoogenboezem RM, Mooren F, Kuppe C, Miesen P, Grünberg K, Ijzermans T, Steenbergen EJ, Czogalla J, Schreuder MF, Sommerdijk N, Akiva A, Boor P, Puelles VG, Floege J, Huber TB; COVID Moonshot consortium; van Rij RP, Costa IG, Schneider RK, Smeets B, Kramann R. Jansen J, et al. Cell Stem Cell. 2022 Feb 3;29(2):217-231.e8. doi: 10.1016/j.stem.2021.12.010. Epub 2021 Dec 25. Cell Stem Cell. 2022. PMID: 35032430 Free PMC article.
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC; COVID Moonshot Consortium‡; Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, Aschenbrenner JC, Balcomb BH, Bar-David E, Barr H, Ben-Shmuel A, Bennett J, Bilenko VA, Borden B, Boulet P, Bowman GR, Brewitz L, Brun J, Bvnbs S, Calmiano M, Carbery A, Carney DW, Cattermole E, Chang E, Chernyshenko E, Clyde A, Coffland JE, Cohen G, Cole JC, Contini A, Cox L, Croll TI, Cvitkovic M, De Jonghe S, Dias A, Donckers K, Dotson DL, Douangamath A, Duberstein S, Dudgeon T, Dunnett LE, Eastman P, Erez N, Eyermann CJ, Fairhead M, Fate G, Fedorov O, Fernandes RS, Ferrins L, Foster R, Foster H, Fraisse L, Gabizon R, García-Sastre A, Gawriljuk VO, Gehrtz P, Gileadi C, Giroud C, Glass WG, Glen RC, Glinert I, Godoy AS, Gorichko M, Gorrie-Stone T, Griffen EJ, Haneef A, Hassell Hart S, Heer J, Henry M, Hill M, Horrell S, Huang QYJ, Huliak VD, Hurley MFD, Israely T, Jajack A, Jansen J, Jnoff E, Jochmans D, John T, Kaminow B, Kang L, Kantsadi AL, Kenny PW, Kiappes JL, Kinakh SO, Kovar B, Krojer T, La VNT, Laghnimi-Hahn S, Lefker BA, Levy H, Lithgo RM, Logvinenko IG, Lukacik P, Macdonald HB, M… See abstract for full author list ➔ Boby ML, et al. Among authors: fairhead m. Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10. Science. 2023. PMID: 37943932 Free PMC article.
Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening.
Resnick E, Bradley A, Gan J, Douangamath A, Krojer T, Sethi R, Geurink PP, Aimon A, Amitai G, Bellini D, Bennett J, Fairhead M, Fedorov O, Gabizon R, Gan J, Guo J, Plotnikov A, Reznik N, Ruda GF, Díaz-Sáez L, Straub VM, Szommer T, Velupillai S, Zaidman D, Zhang Y, Coker AR, Dowson CG, Barr HM, Wang C, Huber KVM, Brennan PE, Ovaa H, von Delft F, London N. Resnick E, et al. Among authors: fairhead m. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22. J Am Chem Soc. 2019. PMID: 31060360 Free PMC article.
Covalently constrained 'Di-Gembodies' enable parallel structure solutions by cryo-EM.
Yi G, Mamalis D, Ye M, Carrique L, Fairhead M, Li H, Duerr KL, Zhang P, Sauer DB, von Delft F, Davis BG, Gilbert RJC. Yi G, et al. Among authors: fairhead m. Nat Chem Biol. 2025 Aug 15:10.1038/s41589-025-01972-7. doi: 10.1038/s41589-025-01972-7. Online ahead of print. Nat Chem Biol. 2025. PMID: 40817135 Free PMC article.
Combined crystallographic fragment screening and deep mutational scanning enable discovery of Zika virus NS2B-NS3 protease inhibitors.
Ni X, Richardson RB, Godoy AS, Ferla MP, Kikawa C, Scheen J, Hannon WW, Capkin E, Lahav N, Balcomb BH, Marples PG, Fairhead M, Wang S, Williams EP, Tomlinson CWE, Aschenbrenner JC, Lithgo RM, Winokan M, Giroud C, Dolci I, Fernandes RS, Oliva G, Chandran AV, Xavier MA, Walsh MA, Thompson W, Bloom JD, Kenton NT, Lee AA, von Delft A, Barr H, Kirkegaard K, Koekemoer L, Fearon D, Evans MJ, von Delft F. Ni X, et al. Among authors: fairhead m. Nat Commun. 2025 Oct 8;16(1):8930. doi: 10.1038/s41467-025-63602-z. Nat Commun. 2025. PMID: 41062463 Free PMC article.
Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.
von Delft F, Ni X, Richardson R, Godoy A, Ferla M, Kikawa C, Scheen J, Hannon W, Capkin E, Lahav N, Balcomb B, Marples P, Fairhead M, Wang S, Williams E, Tomlinson C, Aschenbrenner J, Lithgo R, Winokan M, Giroud C, Chandran A, Walsh M, Thompson W, Bloom J, Barr H, Kirkegaard K, Koekemoer L, Fearon D, Evans M. von Delft F, et al. Among authors: fairhead m. Res Sq [Preprint]. 2025 Feb 13:rs.3.rs-5876218. doi: 10.21203/rs.3.rs-5876218/v1. Res Sq. 2025. Update in: Nat Commun. 2025 Oct 8;16(1):8930. doi: 10.1038/s41467-025-63602-z. PMID: 39989958 Free PMC article. Updated. Preprint.
42 results