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Page 1
Showing results for fibrin e
Search for Firbria E instead (1 results)
Fibrinogen and fibrin structure and functions.
Mosesson MW. Mosesson MW. J Thromb Haemost. 2005 Aug;3(8):1894-904. doi: 10.1111/j.1538-7836.2005.01365.x. J Thromb Haemost. 2005. PMID: 16102057 Free article. Review.
Each molecule contains two outer D domains connected to a central E domain by a coiled-coil segment. Fibrin is formed after thrombin cleavage of fibrinopeptide A (FPA) from fibrinogen Aalpha-chains, thus initiating fibrin polymerization. ...In addition to its …
Each molecule contains two outer D domains connected to a central E domain by a coiled-coil segment. Fibrin is formed after th …
Like fibrin, (DD)E, the major degradation product of crosslinked fibrin, protects plasmin from inhibition by alpha2-antiplasmin.
Lee AY, Fredenburgh JC, Stewart RJ, Rischke JA, Weitz JI. Lee AY, et al. Thromb Haemost. 2001 Mar;85(3):502-8. Thromb Haemost. 2001. PMID: 11307822
(DD)E and fibrin reduce the rate of plasmin inhibition by alpha2-antiplasmin by 5- and 10-fold, respectively. ...This provides a mechanism to limit the concentration of (DD)E and maintain the fibrin-specificity of t-PA....
(DD)E and fibrin reduce the rate of plasmin inhibition by alpha2-antiplasmin by 5- and 10-fold, respectively. ...This provides …
Reduced fibrin clot permeability on admission and elevated E-selectin at 3 months as novel risk factors of residual pulmonary vascular obstruction in patients with acute pulmonary embolism.
Stępień K, Ząbczyk M, Kopytek M, Natorska J, Zalewski J, Undas A. Stępień K, et al. J Thromb Thrombolysis. 2024 Feb;57(2):248-259. doi: 10.1007/s11239-023-02901-y. Epub 2023 Nov 6. J Thromb Thrombolysis. 2024. PMID: 37932588 Free PMC article.
METHODS: In 79 normotensive noncancer patients (aged 56 13.3 years) with acute PE, we determined fibrin clot permeability (K(s)), clot lysis time (CLT), endogenous thrombin potential (ETP), fibrinolysis proteins, oxidative stress markers, and E-selectin on admission …
METHODS: In 79 normotensive noncancer patients (aged 56 13.3 years) with acute PE, we determined fibrin clot permeability (K(s)), clo …
Fibrinogen, Fibrin, and Fibrin Degradation Products in COVID-19.
Kangro K, Wolberg AS, Flick MJ. Kangro K, et al. Curr Drug Targets. 2022;23(17):1593-1602. doi: 10.2174/1389450123666220826162900. Curr Drug Targets. 2022. PMID: 36029073 Free PMC article. Review.
Severe COVID-19 is associated with a profound perturbation of circulating fibrinogen, intra- and extravascular fibrin deposition and persistence, and fibrin degradation. Current findings suggest high levels of fibrinogen and the fibrin degradation product D-d …
Severe COVID-19 is associated with a profound perturbation of circulating fibrinogen, intra- and extravascular fibrin deposition and …
Current View on the Molecular Mechanisms Underlying Fibrin(ogen)-Dependent Inflammation.
Yakovlev S, Strickland DK, Medved L. Yakovlev S, et al. Thromb Haemost. 2022 Nov;122(11):1858-1868. doi: 10.1055/a-1910-4538. Epub 2022 Jul 27. Thromb Haemost. 2022. PMID: 35896433 Free PMC article. Review.
The second mechanism includes bridging of leukocytes to the endothelium by fibrin degradation product E(1) fragment through its interaction with leukocyte receptor CD11c and endothelial VE-cadherin to promote leukocyte transmigration. The role of E(1) in prom …
The second mechanism includes bridging of leukocytes to the endothelium by fibrin degradation product E(1) fragment through it …
Fibrin in peritonitis. I. Beneficial and adverse effects of fibrin in experimental E. coli peritonitis.
Ahrenholz DH, Simmons RL. Ahrenholz DH, et al. Surgery. 1980 Jul;88(1):41-7. Surgery. 1980. PMID: 6992321
As few as 10(2) E. coli per fibrin clot produce abscesses, but 10(7) or more are required to produce death; without fibrin less than 10(7) E. coli neither kill nor produce intraperitoneal infections. Both late death and abscess size with 2 X 10(8) E
As few as 10(2) E. coli per fibrin clot produce abscesses, but 10(7) or more are required to produce death; without fibrin
The (DD)E complex is maintained by a composite fibrin polymerization site.
Moskowitz KA, Budzynski AZ. Moskowitz KA, et al. Biochemistry. 1994 Nov 8;33(44):12937-44. doi: 10.1021/bi00248a001. Biochemistry. 1994. PMID: 7524657
First, the (DD)E complex was reversibly dissociated by peptides derived from the alpha-chain NH2-terminus of fibrin having a minimal sequence of GPR (alpha 17-19). ...The (DD)E complex can thus be considered as a soluble model of fibrin clot.(ABSTRACT …
First, the (DD)E complex was reversibly dissociated by peptides derived from the alpha-chain NH2-terminus of fibrin having a m …
Decoration of Fibrin with Extracellular Chaperones.
Talens S, Leebeek FWG, Veerhuis R, Rijken DC. Talens S, et al. Thromb Haemost. 2019 Oct;119(10):1624-1631. doi: 10.1055/s-0039-1693701. Epub 2019 Aug 22. Thromb Haemost. 2019. PMID: 31437862 Free article.
BACKGROUND: Many proteins bind to fibrin during clot formation in plasma. We previously identified by mass spectrometry the most abundant proteins that noncovalently bind to fibrin clots. ...This provides evidence for the generation of cross-beta structures during …
BACKGROUND: Many proteins bind to fibrin during clot formation in plasma. We previously identified by mass spectrometry the most abun …
Update on antithrombin I (fibrin).
Mosesson MW. Mosesson MW. Thromb Haemost. 2007 Jul;98(1):105-8. Thromb Haemost. 2007. PMID: 17597999 Review.
Antithrombin I (fibrin) is an important inhibitor of thrombin generation that functions by sequestering thrombin in the forming fibrin clot, and also by reducing the catalytic activity of fibrinbound thrombin. Thrombin binding to fibrin takes place at two cla …
Antithrombin I (fibrin) is an important inhibitor of thrombin generation that functions by sequestering thrombin in the forming fi
Fibrin nanostructures for biomedical applications.
Riedelová-Reicheltová Z, Brynda E, Riedel T. Riedelová-Reicheltová Z, et al. Physiol Res. 2016 Oct 20;65(Suppl 2):S263-S272. doi: 10.33549/physiolres.933428. Physiol Res. 2016. PMID: 27762592 Free article.
In this paper fibrin nanostructures prepared using a technique based on the catalytic effect of fibrin-bound thrombin are presented. This technique enables surface-attached thin fibrin networks to form with precisely regulated morphology without the developme …
In this paper fibrin nanostructures prepared using a technique based on the catalytic effect of fibrin-bound thrombin are pres …
3,553 results