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1986 2
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Page 1
Preclinical concept studies showing advantage of an inhaled anti-CTGF/CCN2 protein for pulmonary fibrosis treatment.
Neiens V, Hansbauer EM, Jaquin TJ, Peper-Gabriel JK, Mahavadi P, Snyder ME, Grill MJ, Wurzenberger C, Konitsiotis A, Estrada-Bernal A, Heinig K, Fysikopoulos A, Schwenck N, Grüner S, Bartoschek D, Mosebach T, Kerstan S, Wrennall J, Richter M, Noda K, Hoetzenecker K, Burgess JK, Tarran R, Wurzenberger C, Wichmann KR, Biehler J, Müller KW, Guenther A, Eickelberg O, Fitzgerald MF, Olwill SA, Matschiner G, Pavlidou M. Neiens V, et al. Among authors: fitzgerald mf. Nat Commun. 2025 Apr 5;16(1):3251. doi: 10.1038/s41467-025-58568-x. Nat Commun. 2025. PMID: 40185752 Free PMC article.
Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction.
Heinzelmann K, Fysikopoulos A, Jaquin TJ, Peper-Gabriel JK, Hansbauer EM, Grüner S, Prassler J, Wurzenberger C, Kennedy JGC, Snead JY, Wrennall JA, Heinig K, Wurzenberger C, Bel Aiba RS, Tarran R, Livraghi-Butrico A, Fitzgerald MF, Anderson GP, Rothe C, Matschiner G, Olwill SA, Hagner M. Heinzelmann K, et al. Among authors: fitzgerald mf. Am J Physiol Lung Cell Mol Physiol. 2025 Jan 1;328(1):L75-L92. doi: 10.1152/ajplung.00059.2024. Epub 2024 Nov 5. Am J Physiol Lung Cell Mol Physiol. 2025. PMID: 39499257 Free article.
Etiologics ltd.
Campbell DA, Fitzgerald MF. Campbell DA, et al. Among authors: fitzgerald mf. Pharmacogenomics. 2003 May;4(3):351-7. doi: 10.1517/phgs.4.3.351.22697. Pharmacogenomics. 2003. PMID: 12718725
Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma.
Matschiner G, Fitzgerald MF, Moebius U, Hohlbaum AM, Gille H, Jensen K, Kirchfeld K, Rattenstetter B, Laforge A, Bel Aiba RS, Ciccotosto J, Nyugen H, Foster ML, Snouwaert JN, Nguyen M, Koller BH, Matis L, Anderson GP, Olwill SA. Matschiner G, et al. Among authors: fitzgerald mf. J Allergy Clin Immunol. 2023 Apr;151(4):966-975. doi: 10.1016/j.jaci.2022.12.815. Epub 2022 Dec 30. J Allergy Clin Immunol. 2023. PMID: 36592703 Free article.
Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases.
von Nussbaum F, Li VM, Allerheiligen S, Anlauf S, Bärfacker L, Bechem M, Delbeck M, Fitzgerald MF, Gerisch M, Gielen-Haertwig H, Haning H, Karthaus D, Lang D, Lustig K, Meibom D, Mittendorf J, Rosentreter U, Schäfer M, Schäfer S, Schamberger J, Telan LA, Tersteegen A. von Nussbaum F, et al. Among authors: fitzgerald mf. ChemMedChem. 2015 Jul;10(7):1163-73. doi: 10.1002/cmdc.201500131. Epub 2015 Jun 17. ChemMedChem. 2015. PMID: 26083237 Free PMC article.
19 results