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1981 3
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1985 7
1986 2
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1988 5
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1992 5
1993 3
1994 2
1995 3
1996 3
1997 3
1998 2
2000 1
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2002 1
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2004 3
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130 results

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Page 1
Targeting Huntingtin Expression in Patients with Huntington's Disease.
Tabrizi SJ, Leavitt BR, Landwehrmeyer GB, Wild EJ, Saft C, Barker RA, Blair NF, Craufurd D, Priller J, Rickards H, Rosser A, Kordasiewicz HB, Czech C, Swayze EE, Norris DA, Baumann T, Gerlach I, Schobel SA, Paz E, Smith AV, Bennett CF, Lane RM; Phase 1–2a IONIS-HTTRx Study Site Teams. Tabrizi SJ, et al. N Engl J Med. 2019 Jun 13;380(24):2307-2316. doi: 10.1056/NEJMoa1900907. Epub 2019 May 6. N Engl J Med. 2019. PMID: 31059641 Clinical Trial.
Antisense oligonucleotide-mediated MSH3 suppression reduces somatic CAG repeat expansion in Huntington's disease iPSC-derived striatal neurons.
Bunting EL, Donaldson J, Cumming SA, Olive J, Broom E, Miclăuș M, Hamilton J, Tegtmeyer M, Zhao HT, Brenton J, Lee WS, Handsaker RE, Li S, Ford B, Ryten M, McCarroll SA, Kordasiewicz HB, Monckton DG, Balmus G, Flower M, Tabrizi SJ. Bunting EL, et al. Among authors: flower m. Sci Transl Med. 2025 Feb 12;17(785):eadn4600. doi: 10.1126/scitranslmed.adn4600. Epub 2025 Feb 12. Sci Transl Med. 2025. PMID: 39937881
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons.
Hölbling BV, Gupta Y, Marchi PM, Atilano ML, Flower M, Ureña E, Goulden RA, Dobbs HK, Katona E, Mikheenko A, Giblin A, Awan AR, Fisher-Ward CL, O'Brien N, Vaizoglu D, Kempthorne L, Wilson KM, Gittings LM, Carcolé M, Ruepp MD, Mizielinska S, Partridge L, Fratta P, Tabrizi SJ, Selvaraj BT, Chandran S, Armstrong E, Whiting P, Isaacs AM. Hölbling BV, et al. Among authors: flower m. Cell Rep. 2025 May 27;44(5):115695. doi: 10.1016/j.celrep.2025.115695. Epub 2025 May 10. Cell Rep. 2025. PMID: 40349338 Free article.
Therapeutic strategies for Huntington's disease.
Estevez-Fraga C, Flower MD, Tabrizi SJ. Estevez-Fraga C, et al. Among authors: flower md. Curr Opin Neurol. 2020 Aug;33(4):508-518. doi: 10.1097/WCO.0000000000000835. Curr Opin Neurol. 2020. PMID: 32657893 Review.
Genetic modifiers of repeat expansion disorders.
Rajagopal S, Donaldson J, Flower M, Hensman Moss DJ, Tabrizi SJ. Rajagopal S, et al. Among authors: flower m. Emerg Top Life Sci. 2023 Dec 14;7(3):325-337. doi: 10.1042/ETLS20230015. Emerg Top Life Sci. 2023. PMID: 37861103 Free PMC article.
130 results