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Page 1
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.
Korsunsky I, Wei K, Pohin M, Kim EY, Barone F, Major T, Taylor E, Ravindran R, Kemble S, Watts GFM, Jonsson AH, Jeong Y, Athar H, Windell D, Kang JB, Friedrich M, Turner J, Nayar S, Fisher BA, Raza K, Marshall JL, Croft AP, Tamura T, Sholl LM, Vivero M, Rosas IO, Bowman SJ, Coles M, Frei AP, Lassen K, Filer A, Powrie F, Buckley CD, Brenner MB, Raychaudhuri S. Korsunsky I, et al. Among authors: frei ap. Med. 2022 Jul 8;3(7):481-518.e14. doi: 10.1016/j.medj.2022.05.002. Epub 2022 May 31. Med. 2022. PMID: 35649411 Free PMC article.
IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies.
Friedrich M, Pohin M, Jackson MA, Korsunsky I, Bullers SJ, Rue-Albrecht K, Christoforidou Z, Sathananthan D, Thomas T, Ravindran R, Tandon R, Peres RS, Sharpe H, Wei K, Watts GFM, Mann EH, Geremia A, Attar M; Oxford IBD Cohort Investigators; Roche Fibroblast Network Consortium; McCuaig S, Thomas L, Collantes E, Uhlig HH, Sansom SN, Easton A, Raychaudhuri S, Travis SP, Powrie FM. Friedrich M, et al. Nat Med. 2021 Nov;27(11):1970-1981. doi: 10.1038/s41591-021-01520-5. Epub 2021 Oct 21. Nat Med. 2021. PMID: 34675383 Free PMC article.
Molecular and spatial analysis of tertiary lymphoid structures in Sjogren's syndrome.
Nayar S, Turner JD, Asam S, Fennell E, Pugh M, Colafrancesco S, Berardicurti O, Smith CG, Flint J, Teodosio A, Iannizzotto V, Gardner DH, van Roon J, Korsunsky I, Howdle D; Roche Fibroblast Network Consortium; Frei AP, Lassen KG, Bowman SJ, Ng WF, Croft AP, Filer A, Fisher BA, Buckley CD, Barone F. Nayar S, et al. Among authors: frei ap. Nat Commun. 2025 Jan 2;16(1):5. doi: 10.1038/s41467-024-54686-0. Nat Commun. 2025. PMID: 39747819 Free PMC article.
Author Correction: Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity.
Wang CJ, Petersone L, Edner NM, Heuts F, Ovcinnikovs V, Ntavli E, Kogimtzis A, Fabri A, Elfaki Y, Houghton LP, Hosse RJ, Schubert DA, Frei AP, Ross EM, Walker LSK. Wang CJ, et al. Among authors: frei ap. Nat Commun. 2023 Sep 15;14(1):5724. doi: 10.1038/s41467-023-41483-4. Nat Commun. 2023. PMID: 37714833 Free PMC article. No abstract available.
A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS.
Maccari ME, Fuchs S, Kury P, Andrieux G, Völkl S, Bengsch B, Lorenz MR, Heeg M, Rohr J, Jägle S, Castro CN, Groß M, Warthorst U, König C, Fuchs I, Speckmann C, Thalhammer J, Kapp FG, Seidel MG, Dückers G, Schönberger S, Schütz C, Führer M, Kobbe R, Holzinger D, Klemann C, Smisek P, Owens S, Horneff G, Kolb R, Naumann-Bartsch N, Miano M, Staniek J, Rizzi M, Kalina T, Schneider P, Erxleben A, Backofen R, Ekici A, Niemeyer CM, Warnatz K, Grimbacher B, Eibel H, Mackensen A, Frei AP, Schwarz K, Boerries M, Ehl S, Rensing-Ehl A. Maccari ME, et al. Among authors: frei ap. J Exp Med. 2021 Feb 1;218(2):e20192191. doi: 10.1084/jem.20192191. J Exp Med. 2021. PMID: 33170215 Free PMC article.
Deep Phenotyping of CD11c+ B Cells in Systemic Autoimmunity and Controls.
Rincon-Arevalo H, Wiedemann A, Stefanski AL, Lettau M, Szelinski F, Fuchs S, Frei AP, Steinberg M, Kam-Thong T, Hatje K, Keller B, Warnatz K, Radbruch A, Lino AC, Schrezenmeier E, Dörner T. Rincon-Arevalo H, et al. Among authors: frei ap. Front Immunol. 2021 Mar 12;12:635615. doi: 10.3389/fimmu.2021.635615. eCollection 2021. Front Immunol. 2021. PMID: 33777025 Free PMC article.
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