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42 results

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Page 1
Opportunities and insights from pharmaceutical companies on the current use of new approach methodologies in nonclinical safety assessment.
Shenton J, Bousnina I, Oropallo M, David R, Weir L, Baker TK, Dunmore HM, Villenave R, McElroy M, Pettersen B, Kokate T, Fuller CL, Homan KA, Hudry E, Wood C, Gunter S. Shenton J, et al. Among authors: fuller cl. Drug Discov Today. 2025 Apr;30(4):104328. doi: 10.1016/j.drudis.2025.104328. Epub 2025 Mar 12. Drug Discov Today. 2025. PMID: 40086787 Free article. Review.
Current nonclinical approaches for immune assessments of immuno-oncology biotherapeutics.
Grimaldi C, Ibraghimov A, Kiessling A, Rattel B, Ji C, Fuller CL, Brennan FR, Regenass-Lechner F, Shenton J, Price KD, Piché MS, Steeves MA, Prell R, Dudal S, Kronenberg S, Freebern W, Blanset D. Grimaldi C, et al. Among authors: fuller cl. Drug Discov Today. 2023 Feb;28(2):103440. doi: 10.1016/j.drudis.2022.103440. Epub 2022 Nov 12. Drug Discov Today. 2023. PMID: 36375739 Free article. Review.
Assessing the impact and risk of immunomodulatory compounds on pregnancy.
Kwak-Kim J, Maier CC, Villano CM, Bowman CJ, Brennan FR, Stanislaus D, Hillegas A, Krayer J, Prell RA, Papenfuss TL, Cauvin A, Gamse J, Dahlman A, Enright B, Leshin L, Rao GK, Helms W, Fuller CL, Yang X, Chen C, Mitchell-Ryan S. Kwak-Kim J, et al. Among authors: fuller cl. J Reprod Immunol. 2025 Jun;169:104453. doi: 10.1016/j.jri.2025.104453. Epub 2025 Feb 16. J Reprod Immunol. 2025. PMID: 39999662 Free article. Review.
Multicentre analysis of severe perioperative adverse events in children undergoing surgery who were infected with SARS-CoV-2: a propensity score-adjusted analysis.
Saynhalath R, Sanford EL, Kato MA, Staffa SJ, Zurakowski D, Meier PM, Alex GA, Fuller CL, Rossmann Beel EN, Chhabada S, Poppino KF, Szmuk P, Matava CT, Efune PN; Pediatric Anesthesia COVID-19 Collaborative. Saynhalath R, et al. Among authors: fuller cl. Br J Anaesth. 2025 Feb;134(2):441-452. doi: 10.1016/j.bja.2024.10.005. Epub 2024 Nov 16. Br J Anaesth. 2025. PMID: 39550319
Challenges and gaps in immunosafety evaluation of therapeutics: An IQ DruSafe survey.
Collinge M, Neff-LaFord H, Akella S, Fogal B, Fraser K, Jabbour J, Harper K, Maier CC, Malherbe L, Marshall N, Rao GK, Raman K, Skaggs H, Weber F, Fuller CL. Collinge M, et al. Among authors: fuller cl. Regul Toxicol Pharmacol. 2024 Jun;150:105630. doi: 10.1016/j.yrtph.2024.105630. Epub 2024 Apr 18. Regul Toxicol Pharmacol. 2024. PMID: 38642729
42 results