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Arginase 1 is a key driver of immune suppression in pancreatic cancer.
Menjivar RE, Nwosu ZC, Du W, Donahue KL, Hong HS, Espinoza C, Brown K, Velez-Delgado A, Yan W, Lima F, Bischoff A, Kadiyala P, Salas-Escabillas D, Crawford HC, Bednar F, Carpenter E, Zhang Y, Halbrook CJ, Lyssiotis CA, Pasca di Magliano M. Menjivar RE, et al. Elife. 2023 Feb 2;12:e80721. doi: 10.7554/eLife.80721. Elife. 2023. PMID: 36727849 Free PMC article.
Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer.
Veghini L, Pasini D, Fang R, Delfino P, Filippini D, Neander C, Vicentini C, Fiorini E, Lupo F, D'Agosto SL, Carbone C, Agostini A, Piro G, Rosa D, Bevere M, Markus P, Behrens D, Luchini C, Lawlor RT, Scarpa A, Biffi G, Cheung PF, Siveke JT, Corbo V. Veghini L, et al. Nat Commun. 2024 Dec 3;15(1):10534. doi: 10.1038/s41467-024-54975-8. Nat Commun. 2024. PMID: 39627211 Free PMC article.