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HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis.
Peng X, Sun B, Tang C, Shi C, Xie X, Wang X, Jiang D, Li S, Jia Y, Wang Y, Tang H, Zhong S, Piao M, Cui X, Zhang S, Wang F, Wang Y, Na R, Huang R, Jiang Y, Zhang W, Xu J, Lin K, Guo J, Pan Z, Wang K, Zhao Q, Liu H, Yu B, Ji Y, Zhang J, Li S, Tian J. Peng X, et al. Dev Cell. 2025 Apr 7;60(7):1070-1086.e8. doi: 10.1016/j.devcel.2024.12.011. Epub 2024 Dec 27. Dev Cell. 2025. PMID: 39731912
Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis.
Singh P, Sun J, Cavalera M, Al-Sharify D, Matthes F, Barghouth M, Tengryd C, Dunér P, Persson A, Sundius L, Nitulescu M, Bengtsson E, Rattik S, Engelbertsen D, Orho-Melander M, Nilsson J, Monaco C, Goncalves I, Edsfeldt A. Singh P, et al. Nat Commun. 2024 Dec 9;15(1):10464. doi: 10.1038/s41467-024-50753-8. Nat Commun. 2024. PMID: 39653743 Free PMC article.