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2005 1
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58 results

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Page 1
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver.
Sampaziotis F, Muraro D, Tysoe OC, Sawiak S, Beach TE, Godfrey EM, Upponi SS, Brevini T, Wesley BT, Garcia-Bernardo J, Mahbubani K, Canu G, Gieseck R 3rd, Berntsen NL, Mulcahy VL, Crick K, Fear C, Robinson S, Swift L, Gambardella L, Bargehr J, Ortmann D, Brown SE, Osnato A, Murphy MP, Corbett G, Gelson WTH, Mells GF, Humphreys P, Davies SE, Amin I, Gibbs P, Sinha S, Teichmann SA, Butler AJ, See TC, Melum E, Watson CJE, Saeb-Parsy K, Vallier L. Sampaziotis F, et al. Among authors: gelson wth. Science. 2021 Feb 19;371(6531):839-846. doi: 10.1126/science.aaz6964. Science. 2021. PMID: 33602855 Free PMC article.
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.
Brevini T, Maes M, Webb GJ, John BV, Fuchs CD, Buescher G, Wang L, Griffiths C, Brown ML, Scott WE 3rd, Pereyra-Gerber P, Gelson WTH, Brown S, Dillon S, Muraro D, Sharp J, Neary M, Box H, Tatham L, Stewart J, Curley P, Pertinez H, Forrest S, Mlcochova P, Varankar SS, Darvish-Damavandi M, Mulcahy VL, Kuc RE, Williams TL, Heslop JA, Rossetti D, Tysoe OC, Galanakis V, Vila-Gonzalez M, Crozier TWM, Bargehr J, Sinha S, Upponi SS, Fear C, Swift L, Saeb-Parsy K, Davies SE, Wester A, Hagström H, Melum E, Clements D, Humphreys P, Herriott J, Kijak E, Cox H, Bramwell C, Valentijn A, Illingworth CJR; UK-PBC Consortium; Dahman B, Bastaich DR, Ferreira RD, Marjot T, Barnes E, Moon AM, Barritt AS 4th, Gupta RK, Baker S, Davenport AP, Corbett G, Gorgoulis VG, Buczacki SJA, Lee JH, Matheson NJ, Trauner M, Fisher AJ, Gibbs P, Butler AJ, Watson CJE, Mells GF, Dougan G, Owen A, Lohse AW, Vallier L, Sampaziotis F. Brevini T, et al. Among authors: gelson wth. Nature. 2023 Mar;615(7950):134-142. doi: 10.1038/s41586-022-05594-0. Epub 2022 Dec 5. Nature. 2023. PMID: 36470304 Free PMC article.
Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.
Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL 3rd, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W, Materek PM, Snijders KE, Brown SE, Rimland CA, Simonic I, Davies SE, Jensen KB, Zilbauer M, Gelson WTH, Alexander GJ, Sinha S, Hannan NRF, Wynn TA, Karlsen TH, Melum E, Markaki AE, Saeb-Parsy K, Vallier L. Sampaziotis F, et al. Among authors: gelson wth. Nat Med. 2017 Aug;23(8):954-963. doi: 10.1038/nm.4360. Epub 2017 Jul 3. Nat Med. 2017. PMID: 28671689 Free article.
Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression.
Vionnet J, Torres-Yaguana J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Ferguson J, Quaglia A, Demetris AJ, Lesniak AJ, Elstad M, Delord M, Douiri A, Rebollo-Mesa I, Martinez-Llordella M, Silva JAF, Markmann JF, Sánchez-Fueyo A. Vionnet J, et al. Among authors: gelson w. Am J Transplant. 2025 May;25(5):1045-1058. doi: 10.1016/j.ajt.2024.12.002. Epub 2024 Dec 18. Am J Transplant. 2025. PMID: 39706366 Free article. Clinical Trial.
Successful AAV8 gene therapy on hepatic ex situ machine perfusion for mitochondrial neurogastrointestinal encephalomyopathy.
Brevini T, Swift L, Reynolds H, Ong J, Stopforth RJ, Malam Y, Spiers HV, Jovanovic E, Scaravaglio M, Vakeeswarasarma V, Heslop J, Emmett E, Andreatta B, Athanasiadis E, Cacciottolo TM, Fuchs CD, Trauner M, Hosgood SA, See TC, Pantelis P, Foukaneli D, Gelson WT, Gibbs P, Allinson K, Pettigrew GJ, Duckworth A, Paterson AL, Gorgoulis VG, Thompson RJ, Kaser A, Kosmoliaptsis V, Chinnery PF, Marti R, van den Ameele J, Webb GJ, Watson CJ, Butler AJ, Sampaziotis F. Brevini T, et al. Among authors: gelson wt. J Hepatol. 2025 Aug 5:S0168-8278(25)02388-8. doi: 10.1016/j.jhep.2025.07.022. Online ahead of print. J Hepatol. 2025. PMID: 40774626 Free article.
Hepatitis E case series: A UK experience.
Robins A, Dolman G, Williams S, Gelson W, Mohsen A. Robins A, et al. Among authors: gelson w. J Viral Hepat. 2022 Sep;29(9):817-822. doi: 10.1111/jvh.13714. Epub 2022 Jun 12. J Viral Hepat. 2022. PMID: 35652356
Distinct virologic trajectories in chronic hepatitis B identify heterogeneity in response to nucleos(t)ide analogue therapy.
Wang T, Campbell C, Stockdale AJ, Todd S, McIntyre K, Frankland A, Jaworski J, Glampson B, Papadimitriou D, Mercuri L, Mayer E, Jones CR, Salih H, Roadknight G, Little S, Noble T, Várnai KA, Davis C, Heinson AI, George M, Borca F, English L, Romão L, Ramlakhan D; NIHR HIC Viral Hepatitis and Liver Disease Consortium; Woods K, Davies J, Nastouli E, Khakoo SI, Gelson W, Cooke GS, Barnes E, Matthews PC. Wang T, et al. Among authors: gelson w. JHEP Rep. 2024 Oct 9;7(1):101229. doi: 10.1016/j.jhepr.2024.101229. eCollection 2025 Jan. JHEP Rep. 2024. PMID: 39717508 Free PMC article.
Non-invasive alloimmune risk stratification of long-term liver transplant recipients.
Vionnet J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Feng S, Bucuvalas J, Ferguson J, Quaglia A, Sidorova J, Elstad M, Douiri A, Sánchez-Fueyo A. Vionnet J, et al. Among authors: gelson w. J Hepatol. 2021 Dec;75(6):1409-1419. doi: 10.1016/j.jhep.2021.08.007. Epub 2021 Aug 24. J Hepatol. 2021. PMID: 34437910
58 results