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Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial.
Ahmed I, Hudson J, Innes K, Hernández R, Gillies K, Bruce R, Bell V, Avenell A, Blazeby J, Brazzelli M, Cotton S, Croal B, Forrest M, MacLennan G, Murchie P, Wileman S, Ramsay C; C-GALL Study Group. Ahmed I, et al. BMJ. 2023 Dec 6;383:e075383. doi: 10.1136/bmj-2023-075383. BMJ. 2023. PMID: 38084426 Free PMC article. Clinical Trial.
Negative pressure wound therapy versus usual care in patients with surgical wound healing by secondary intention in the UK (SWHSI-2): an open-label, multicentre, parallel-group, randomised controlled trial.
Arundel C, Mandefield L, Fairhurst C, Baird K, Gkekas A, Saramago P, Chetter I; SWHSI-2 Trial Investigators. Arundel C, et al. Lancet. 2025 May 10;405(10490):1689-1699. doi: 10.1016/S0140-6736(25)00143-6. Epub 2025 Apr 15. Lancet. 2025. PMID: 40250455 Free PMC article. Clinical Trial.
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab.
Lin S, Kennedy NA, Saifuddin A, Sandoval DM, Reynolds CJ, Seoane RC, Kottoor SH, Pieper FP, Lin KM, Butler DK, Chanchlani N, Nice R, Chee D, Bewshea C, Janjua M, McDonald TJ, Sebastian S, Alexander JL, Constable L, Lee JC, Murray CD, Hart AL, Irving PM, Jones GR, Kok KB, Lamb CA, Lees CW, Altmann DM, Boyton RJ, Goodhand JR, Powell N, Ahmad T; CLARITY IBD study. Lin S, et al. Nat Commun. 2022 Mar 16;13(1):1379. doi: 10.1038/s41467-022-28517-z. Nat Commun. 2022. PMID: 35296643 Free PMC article.
Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study.
Liu Z, Le K, Zhou X, Alexander JL, Lin S, Bewshea C, Chanchlani N, Nice R, McDonald TJ, Lamb CA, Sebastian S, Kok K, Lees CW, Hart AL, Pollok RC, Boyton RJ, Altmann DM, Pollock KM, Goodhand JR, Kennedy NA, Ahmad T, Powell N; CLARITY study investigators. Liu Z, et al. Lancet Gastroenterol Hepatol. 2023 Feb;8(2):145-156. doi: 10.1016/S2468-1253(22)00389-2. Epub 2022 Dec 5. Lancet Gastroenterol Hepatol. 2023. PMID: 36481043 Free PMC article.
Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery.
Edwards MR, Forbes G, MacDonald N, Berdunov V, Mihaylova B, Dias P, Thomson A, Grocott MP, Mythen MG, Gillies MA, Sander M, Phan TD, Evered L, Wijeysundera DN, McCluskey SA, Aldecoa C, Ripollés-Melchor J, Hofer CK, Abukhudair H, Szczeklik W, Grigoras I, Hajjar LA, Kahan BC, Pearse RM; OPTIMISE II investigators. Edwards MR, et al. BMJ Open. 2019 Jan 15;9(1):e023455. doi: 10.1136/bmjopen-2018-023455. BMJ Open. 2019. PMID: 30647034 Free PMC article.
Modification and validation of the Bluebelle Wound Healing Questionnaire (WHQ) for assessing surgical site infection in wounds healing by secondary intention.
Macefield R, Mandefield L, Blazeby JM, Fairhurst C, Baird K, Arundel C, Chetter I, Martin BC, Hewitt C, Gkekas A, Mott A, Saramago Goncalves DP, Swan S, Torgerson D, Wilkinson J, Zahra S, Dixon S, Hatfield J, Oswald A, Dumville J, Lee MM, Pinkney T, Stubbs N, Wilson L, Clothier A, Bosanquet D, Blow M, Price C, Todd J, Munro T, Pillay W, Pradhan A, Garnham A, Wall M, Powezka K, Syed A, Gerrard D, Croucher A, Hadjievangelou N, Firth A, Roe T, Smith G, Bicknell C, Carr C, Negbenose E, Tarusan L, Vesey A, Wilson D, Bell D, Fletcher J, Greenwood C, Wallace T, Vallabhaneni S, Holder S, Williams J, Sim S, Tambyraja AL, Kerray F, Ng A, Sylvester M, Slater L, Rashid ST, Palacios A, Feld K, Nandhra S, Stansby G, Parr N, Jones L, Milne J, Stubbs C, Hinchliffe R, Twine C, Antoniou GA, Corbett C, Munt S, Warran S, Fletcher R, Al-Jundi W, Burrows M, Stather P, Barnes R, Woodrow T, Adams B, Agu O, Gleeson Y, D'Souza R, Erete L, Jones S, Checketts C, Bajic D, Matravers R, Loftus I, Budge J, Azhar B, Juszczak M, Syed A, Hancox R, Pearce C, Suggett N, Whitehouse A, Kuhan G, Premnath S, Dattani N, Hollings V, Khasawneh F, AlShakarchi J, Packer E. Macefield R, et al. Among authors: gleeson y. J Tissue Viability. 2025 Aug;34(3):100889. doi: 10.1016/j.jtv.2025.100889. Epub 2025 Mar 18. J Tissue Viability. 2025. PMID: 40359686 Free article.