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23 results

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Page 1
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
ASCEND Study Collaborative Group; Bowman L, Mafham M, Wallendszus K, Stevens W, Buck G, Barton J, Murphy K, Aung T, Haynes R, Cox J, Murawska A, Young A, Lay M, Chen F, Sammons E, Waters E, Adler A, Bodansky J, Farmer A, McPherson R, Neil A, Simpson D, Peto R, Baigent C, Collins R, Parish S, Armitage J. ASCEND Study Collaborative Group, et al. N Engl J Med. 2018 Oct 18;379(16):1529-1539. doi: 10.1056/NEJMoa1804988. Epub 2018 Aug 26. N Engl J Med. 2018. PMID: 30146931 Free article. Clinical Trial.
MICAL2 Promotes Pancreatic Cancer Growth and Metastasis.
Garg B, Khan S, Courelli AS, Panneerpandian P, Sheik Pran Babu D, Mose ES, Gulay KCM, Sharma S, Sood D, Wenzel AT, Martsinkovskiy A, Rajbhandari N, Patel J, Jaquish D, Esparza E, Jaque K, Aggarwal N, Lambies G, D'Ippolito A, Austgen K, Johnston B, Orlando DA, Jang GH, Gallinger S, Goodfellow E, Brodt P, Commisso C, Tamayo P, Mesirov JP, Tiriac H, Lowy AM. Garg B, et al. Among authors: goodfellow e. Cancer Res. 2025 Mar 14;85(6):1049-1063. doi: 10.1158/0008-5472.CAN-24-0744. Cancer Res. 2025. PMID: 39745352 Free PMC article.
Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus.
ASCEND Study Collaborative Group; Bowman L, Mafham M, Wallendszus K, Stevens W, Buck G, Barton J, Murphy K, Aung T, Haynes R, Cox J, Murawska A, Young A, Lay M, Chen F, Sammons E, Waters E, Adler A, Bodansky J, Farmer A, McPherson R, Neil A, Simpson D, Peto R, Baigent C, Collins R, Parish S, Armitage J. ASCEND Study Collaborative Group, et al. N Engl J Med. 2018 Oct 18;379(16):1540-1550. doi: 10.1056/NEJMoa1804989. Epub 2018 Aug 26. N Engl J Med. 2018. PMID: 30146932 Free article. Clinical Trial.
Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor.
Vallée F, Casás-Selves M, Bubenik M, Duplessis M, Sow B, Suarez C, Sangiorgi B, Li L, Hyer M, Papp R, Leclaire ME, Perryman AL, Liu B, Surprenant S, Mochirian P, Pau V, Maderova Z, Mader P, Yin SY, Goodfellow E, Roulston A, Stocco R, Godbout C, Baruah P, Bonneau-Fortin A, Schonhoft JD, Nejad P, Norman D, Truong VL, Crane S, Attia MA, Mao D, Sicheri F, Marshall CG, Zimmermann M, Bendahan D, Gallant M, Black WC. Vallée F, et al. Among authors: goodfellow e. J Med Chem. 2025 Jun 12;68(11):10631-10647. doi: 10.1021/acs.jmedchem.5c00529. Epub 2025 May 16. J Med Chem. 2025. PMID: 40378279 Clinical Trial.
The PLK4 inhibitor RP-1664 demonstrates potent single-agent efficacy in neuroblastoma models through a dual mechanism of sensitivity.
Maris J, Soria-Bretones I, Casás-Selves M, Samanta M, Groff D, Murray J, Fletcher J, Farrel A, Pastor S, Patel K, Goodfellow EG, Li L, Caron C, Shiwram A, Kim H, Henry D, Laterreur N, Bowlan J, Krytska K, Neuhauser S, Stearns T, Schubert J, Wu J, Surrey L, Álvarez-Quilón A, Vallée F, Nejad P, Schonhoft J, Li J, Veloso A, Young J, Hyer M, Morris S, Mossé YP, Marshall G, Haber M, Zimmermann M. Maris J, et al. Among authors: goodfellow eg. Res Sq [Preprint]. 2025 Jul 29:rs.3.rs-7014295. doi: 10.21203/rs.3.rs-7014295/v1. Res Sq. 2025. PMID: 40766251 Free PMC article. Preprint.
Therapies for active rheumatoid arthritis after methotrexate failure.
O'Dell JR, Mikuls TR, Taylor TH, Ahluwalia V, Brophy M, Warren SR, Lew RA, Cannella AC, Kunkel G, Phibbs CS, Anis AH, Leatherman S, Keystone E; CSP 551 RACAT Investigators. O'Dell JR, et al. N Engl J Med. 2013 Jul 25;369(4):307-18. doi: 10.1056/NEJMoa1303006. Epub 2013 Jun 11. N Engl J Med. 2013. PMID: 23755969 Free article. Clinical Trial.
MICAL2 Is a Super Enhancer Associated Gene that Promotes Pancreatic Cancer Growth and Metastasis.
Garg B, Khan S, Babu DS, Mose E, Gulay K, Sharma S, Sood D, Wenzel AT, Martsinkovskiy A, Patel J, Jaquish D, Lambies G, D'Ippolito A, Austgen K, Johnston B, Orlando D, Jang GH, Gallinger S, Goodfellow E, Brodt P, Commisso C, Tamayo P, Mesirov JP, Tiriac H, Lowy AM. Garg B, et al. Among authors: goodfellow e. bioRxiv [Preprint]. 2024 Jun 30:2024.06.26.600548. doi: 10.1101/2024.06.26.600548. bioRxiv. 2024. PMID: 38979336 Free PMC article. Preprint.
Design and Synthesis of a Trifunctional Molecular System "Programmed" to Block Epidermal Growth Factor Receptor Tyrosine Kinase, Induce High Levels of DNA Damage, and Inhibit the DNA Repair Enzyme (Poly(ADP-ribose) Polymerase) in Prostate Cancer Cells.
Schmitt J, Huang S, Goodfellow E, Williams C, Jean-Claude BJ. Schmitt J, et al. Among authors: goodfellow e. J Med Chem. 2020 Jun 11;63(11):5752-5762. doi: 10.1021/acs.jmedchem.9b02008. Epub 2020 Jun 2. J Med Chem. 2020. PMID: 32484346
23 results