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2011 1
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Page 1
Toward personalized immunotherapy in sepsis: The PROVIDE randomized clinical trial.
Leventogiannis K, Kyriazopoulou E, Antonakos N, Kotsaki A, Tsangaris I, Markopoulou D, Grondman I, Rovina N, Theodorou V, Antoniadou E, Koutsodimitropoulos I, Dalekos G, Vlachogianni G, Akinosoglou K, Koulouras V, Komnos A, Kontopoulou T, Prekates A, Koutsoukou A, van der Meer JWM, Dimopoulos G, Kyprianou M, Netea MG, Giamarellos-Bourboulis EJ. Leventogiannis K, et al. Among authors: grondman i. Cell Rep Med. 2022 Nov 15;3(11):100817. doi: 10.1016/j.xcrm.2022.100817. Cell Rep Med. 2022. PMID: 36384100 Free PMC article. Clinical Trial.
Systemic inflammation impairs myelopoiesis and interferon type I responses in humans.
Keramati F, Leijte GP, Bruse N, Grondman I, Habibi E, Ruiz-Moreno C, Megchelenbrink W, Peters van Ton AM, Heesakkers H, Bremmers ME, van Grinsven E, Tesselaar K, van Staveren S, van der Velden WJ, Preijers FW, Te Pas B, van de Loop R, Gerretsen J, Netea MG, Stunnenberg HG, Pickkers P, Kox M. Keramati F, et al. Among authors: grondman i. Nat Immunol. 2025 May;26(5):737-747. doi: 10.1038/s41590-025-02136-4. Epub 2025 Apr 18. Nat Immunol. 2025. PMID: 40251340 Free PMC article.
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19.
Karagiannis F, Peukert K, Surace L, Michla M, Nikolka F, Fox M, Weiss P, Feuerborn C, Maier P, Schulz S, Al B, Seeliger B, Welte T, David S, Grondman I, de Nooijer AH, Pickkers P, Kleiner JL, Berger MM, Brenner T, Putensen C; Bonn COVIMMUNE Consortium; Kato H, Garbi N, Netea MG, Hiller K, Placek K, Bode C, Wilhelm C. Karagiannis F, et al. Among authors: grondman i. Nature. 2022 Sep;609(7928):801-807. doi: 10.1038/s41586-022-05128-8. Epub 2022 Jul 28. Nature. 2022. PMID: 35901960 Free PMC article.
Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination.
Li W, Zhang Z, Kumar S, Botey-Bataller J, Zoodsma M, Ehsani A, Zhan Q, Alaswad A, Zhou L, Grondman I, Koeken V, Yang J, Wang G, Volland S, Crişan TO, Joosten LAB, Illig T, Xu CJ, Netea MG, Li Y. Li W, et al. Among authors: grondman i. Nat Aging. 2025 Apr;5(4):607-621. doi: 10.1038/s43587-025-00819-z. Epub 2025 Mar 5. Nat Aging. 2025. PMID: 40044970 Free PMC article.
In vitro induction of trained immunity in adherent human monocytes.
Domínguez-Andrés J, Arts RJW, Bekkering S, Bahrar H, Blok BA, de Bree LCJ, Bruno M, Bulut Ö, Debisarun PA, Dijkstra H, Cristina Dos Santos J, Ferreira AV, Flores-Gomez D, Groh LA, Grondman I, Helder L, Jacobs C, Jacobs L, Jansen T, Kilic G, Klück V, Koeken VACM, Lemmers H, Moorlag SJCFM, Mourits VP, van Puffelen JH, Rabold K, Röring RJ, Rosati D, Tercan H, van Tuijl J, Quintin J, van Crevel R, Riksen NP, Joosten LAB, Netea MG. Domínguez-Andrés J, et al. Among authors: grondman i. STAR Protoc. 2021 Feb 24;2(1):100365. doi: 10.1016/j.xpro.2021.100365. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33718890 Free PMC article.
A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity.
Li W, Moorlag SJCFM, Koeken VACM, Röring RJ, de Bree LCJ, Mourits VP, Gupta MK, Zhang B, Fu J, Zhang Z, Grondman I, van Meijgaarden KE, Zhou L, Alaswad A, Joosten LAB, van Crevel R, Xu CJ, Netea MG, Li Y. Li W, et al. Among authors: grondman i. Cell Rep. 2023 May 30;42(5):112487. doi: 10.1016/j.celrep.2023.112487. Epub 2023 May 7. Cell Rep. 2023. PMID: 37155329 Free PMC article.
Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis.
Aksu MD, van der Ent T, Zhang Z, Riza AL, de Nooijer AH, Ricaño-Ponce I, Janssen N, Engel JJ, Streata I, Dijkstra H, Lemmers H, Grondman I, Koeken VACM, Antoniadou E, Antonakos N, van de Veerdonk FL, Li Y, Giamarellos-Bourboulis EJ, Netea MG, Ziogas A. Aksu MD, et al. Among authors: grondman i. J Infect. 2024 Dec;89(6):106300. doi: 10.1016/j.jinf.2024.106300. Epub 2024 Sep 30. J Infect. 2024. PMID: 39357572 Free PMC article.
Increased Plasma Heparanase Activity in COVID-19 Patients.
Buijsers B, Yanginlar C, de Nooijer A, Grondman I, Maciej-Hulme ML, Jonkman I, Janssen NAF, Rother N, de Graaf M, Pickkers P, Kox M, Joosten LAB, Nijenhuis T, Netea MG, Hilbrands L, van de Veerdonk FL, Duivenvoorden R, de Mast Q, van der Vlag J. Buijsers B, et al. Among authors: grondman i. Front Immunol. 2020 Oct 6;11:575047. doi: 10.3389/fimmu.2020.575047. eCollection 2020. Front Immunol. 2020. PMID: 33123154 Free PMC article.
The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.
Kuijpers Y, Chu X, Jaeger M, Moorlag SJCFM, Koeken VACM, Zhang B, de Nooijer A, Grondman I, Gupta MK, Janssen N, Mourits VP, de Bree LCJ, de Mast Q, van de Veerdonk FL, Joosten LAB, Li Y, Netea MG, Xu CJ. Kuijpers Y, et al. Among authors: grondman i. Front Immunol. 2022 May 12;13:859387. doi: 10.3389/fimmu.2022.859387. eCollection 2022. Front Immunol. 2022. PMID: 35634344 Free PMC article.
26 results