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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 5
1947 2
1948 7
1949 5
1950 4
1951 4
1952 5
1953 6
1954 4
1955 5
1956 5
1957 6
1958 6
1959 1
1960 4
1961 3
1962 5
1963 3
1964 1
1965 1
1966 1
1967 2
1968 3
1969 1
1970 1
1971 14
1972 6
1973 3
1974 7
1975 4
1976 5
1977 4
1978 2
1979 3
1981 2
1982 3
1983 4
1984 1
1985 5
1987 3
1988 1
1989 1
1990 2
1991 1
1992 2
1993 3
1994 4
1995 6
1996 3
1997 2
1998 5
1999 3
2000 6
2001 8
2002 15
2003 15
2004 15
2005 9
2006 18
2007 20
2008 17
2009 19
2010 13
2011 22
2012 30
2013 33
2014 25
2015 29
2016 18
2017 15
2018 18
2019 20
2020 44
2021 31
2022 28
2023 39
2024 31
2025 18

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701 results

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Page 1
Peptidomics.
Hellinger R, Sigurdsson A, Wu W, Romanova EV, Li L, Sweedler JV, Süssmuth RD, Gruber CW. Hellinger R, et al. Among authors: gruber cw. Nat Rev Methods Primers. 2023 Mar 30;3:25. doi: 10.1038/s43586-023-00205-2. Nat Rev Methods Primers. 2023. PMID: 37250919 Free PMC article.
Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death.
Taft J, Markson M, Legarda D, Patel R, Chan M, Malle L, Richardson A, Gruber C, Martín-Fernández M, Mancini GMS, van Laar JAM, van Pelt P, Buta S, Wokke BHA, Sabli IKD, Sancho-Shimizu V, Chavan PP, Schnappauf O, Khubchandani R, Cüceoğlu MK, Özen S, Kastner DL, Ting AT, Aksentijevich I, Hollink IHIM, Bogunovic D. Taft J, et al. Among authors: gruber c. Cell. 2021 Aug 19;184(17):4447-4463.e20. doi: 10.1016/j.cell.2021.07.026. Epub 2021 Aug 6. Cell. 2021. PMID: 34363755 Free PMC article.
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.
Tobias DK, Merino J, Ahmad A, Aiken C, Benham JL, Bodhini D, Clark AL, Colclough K, Corcoy R, Cromer SJ, Duan D, Felton JL, Francis EC, Gillard P, Gingras V, Gaillard R, Haider E, Hughes A, Ikle JM, Jacobsen LM, Kahkoska AR, Kettunen JLT, Kreienkamp RJ, Lim LL, Männistö JME, Massey R, Mclennan NM, Miller RG, Morieri ML, Most J, Naylor RN, Ozkan B, Patel KA, Pilla SJ, Prystupa K, Raghavan S, Rooney MR, Schön M, Semnani-Azad Z, Sevilla-Gonzalez M, Svalastoga P, Takele WW, Tam CH, Thuesen ACB, Tosur M, Wallace AS, Wang CC, Wong JJ, Yamamoto JM, Young K, Amouyal C, Andersen MK, Bonham MP, Chen M, Cheng F, Chikowore T, Chivers SC, Clemmensen C, Dabelea D, Dawed AY, Deutsch AJ, Dickens LT, DiMeglio LA, Dudenhöffer-Pfeifer M, Evans-Molina C, Fernández-Balsells MM, Fitipaldi H, Fitzpatrick SL, Gitelman SE, Goodarzi MO, Grieger JA, Guasch-Ferré M, Habibi N, Hansen T, Huang C, Harris-Kawano A, Ismail HM, Hoag B, Johnson RK, Jones AG, Koivula RW, Leong A, Leung GKW, Libman IM, Liu K, Long SA, Lowe WL Jr, Morton RW, Motala AA, Onengut-Gumuscu S, Pankow JS, Pathirana M, Pazmino S, Perez D, Petrie JR, Powe CE, Quinteros A, Jain R, Ray D, Ried-Larsen M, Saeed Z, Santhakumar V, Kanbour S, Sarkar … See abstract for full author list ➔ Tobias DK, et al. Among authors: gruber c. Nat Med. 2023 Oct;29(10):2438-2457. doi: 10.1038/s41591-023-02502-5. Epub 2023 Oct 5. Nat Med. 2023. PMID: 37794253 Free PMC article. Review.
Individuals with JAK1 variants are affected by syndromic features encompassing autoimmunity, atopy, colitis, and dermatitis.
Horesh ME, Martin-Fernandez M, Gruber C, Buta S, Le Voyer T, Puzenat E, Lesmana H, Wu Y, Richardson A, Stein D, Hodeib S, Youssef M, Kurowski JA, Feuille E, Pedroza LA, Fuleihan RL, Haseley A, Hovnanian A, Quartier P, Rosain J, Davis G, Mullan D, Stewart O, Patel R, Lee AE, Rubinstein R, Ewald L, Maheshwari N, Rahming V, Chinn IK, Lupski JR, Orange JS, Sancho-Shimizu V, Casanova JL, Abul-Husn NS, Itan Y, Milner JD, Bustamante J, Bogunovic D. Horesh ME, et al. Among authors: gruber c. J Exp Med. 2024 Jun 3;221(6):e20232387. doi: 10.1084/jem.20232387. Epub 2024 Apr 2. J Exp Med. 2024. PMID: 38563820 Free PMC article.
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling.
Ogishi M, Kitaoka K, Good-Jacobson KL, Rinchai D, Zhang B, Wang J, Gies V, Rao G, Nguyen T, Avery DT, Khan T, Smithmyer ME, Mackie J, Yang R, Arias AA, Asano T, Ponsin K, Chaldebas M, Zhang P, Peel JN, Bohlen J, Lévy R, Pelham SJ, Lei WT, Han JE, Fagniez I, Chrabieh M, Laine C, Langlais D, Gruber C, Al Ali F, Rahman M, Aytekin C, Benson B, Dufort MJ, Domingo-Vila C, Moriya K, Shlomchik M, Uzel G, Gray PE, Suan D, Preece K, Chua I, Okada S, Chikuma S, Kiyonari H, Tree TI, Bogunovic D, Gros P, Marr N, Speake C, Oram RA, Béziat V, Bustamante J, Abel L, Boisson B, Korganow AS, Ma CS, Johnson MB, Chamoto K, Boisson-Dupuis S, Honjo T, Casanova JL, Tangye SG. Ogishi M, et al. Among authors: gruber c. Immunity. 2024 Dec 10;57(12):2790-2807.e15. doi: 10.1016/j.immuni.2024.10.014. Epub 2024 Nov 26. Immunity. 2024. PMID: 39603236
Engineered nucleocytosolic vehicles for loading of programmable editors.
Geilenkeuser J, Armbrust N, Steinmaßl E, Du SW, Schmidt S, Binder EMH, Li Y, Warsing NW, Wendel SV, von der Linde F, Schiele EM, Niu X, Stroppel L, Berezin O, Santl TH, Orschmann T, Nelson K, Gruber C, Palczewska G, Menezes CR, Risaliti E, Engfer ZJ, Koleci N, Schmidts A, Geerlof A, Palczewski K, Westmeyer GG, Truong DJ. Geilenkeuser J, et al. Among authors: gruber c. Cell. 2025 May 15;188(10):2637-2655.e31. doi: 10.1016/j.cell.2025.03.015. Epub 2025 Apr 9. Cell. 2025. PMID: 40209705 Free article.
Exonuclease-enhanced prime editors.
Truong DJ, Geilenkeuser J, Wendel SV, Wilming JCH, Armbrust N, Binder EMH, Santl TH, Siebenhaar A, Gruber C, Phlairaharn T, Živanić M, Westmeyer GG. Truong DJ, et al. Among authors: gruber c. Nat Methods. 2024 Mar;21(3):455-464. doi: 10.1038/s41592-023-02162-w. Epub 2024 Feb 1. Nat Methods. 2024. PMID: 38302659 Free PMC article.
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Muratspahić E, Deibler K, Han J, Tomašević N, Jadhav KB, Olivé-Marti AL, Hochrainer N, Hellinger R, Koehbach J, Fay JF, Rahman MH, Hegazy L, Craven TW, Varga BR, Bhardwaj G, Appourchaux K, Majumdar S, Muttenthaler M, Hosseinzadeh P, Craik DJ, Spetea M, Che T, Baker D, Gruber CW. Muratspahić E, et al. Among authors: gruber cw. Nat Commun. 2023 Dec 6;14(1):8064. doi: 10.1038/s41467-023-43718-w. Nat Commun. 2023. PMID: 38052802 Free PMC article.
Back to the Medicinal Chemistry Future.
Giustiniano M, Gruber CW, Kent CN, Trippier PC. Giustiniano M, et al. Among authors: gruber cw. J Med Chem. 2021 Nov 11;64(21):15515-15518. doi: 10.1021/acs.jmedchem.1c01788. Epub 2021 Nov 1. J Med Chem. 2021. PMID: 34719927 No abstract available.
Oxytocin/vasopressin-like neuropeptide signaling in insects.
Muratspahić E, Monjon E, Duerrauer L, Rogers SM, Cullen DA, Vanden Broeck J, Gruber CW. Muratspahić E, et al. Among authors: gruber cw. Vitam Horm. 2020;113:29-53. doi: 10.1016/bs.vh.2019.08.011. Epub 2019 Oct 18. Vitam Horm. 2020. PMID: 32138952 Free PMC article. Review.
701 results