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2019 3
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29 results

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Page 1
ERα-associated translocations underlie oncogene amplifications in breast cancer.
Lee JJ, Jung YL, Cheong TC, Espejo Valle-Inclan J, Chu C, Gulhan DC, Ljungström V, Jin H, Viswanadham VV, Watson EV, Cortés-Ciriano I, Elledge SJ, Chiarle R, Pellman D, Park PJ. Lee JJ, et al. Among authors: gulhan dc. Nature. 2023 Jun;618(7967):1024-1032. doi: 10.1038/s41586-023-06057-w. Epub 2023 May 17. Nature. 2023. PMID: 37198482 Free PMC article.
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.
Färkkilä A, Gulhan DC, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B, Maliga Z, Yapp C, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P, Santagata S, Garcia E, Rodig S, Lako A, Chowdhury D, Shapiro GI, Matulonis UA, Park PJ, Hautaniemi S, Sorger PK, Swisher EM, D'Andrea AD, Konstantinopoulos PA. Färkkilä A, et al. Among authors: gulhan dc. Nat Commun. 2020 Mar 19;11(1):1459. doi: 10.1038/s41467-020-15315-8. Nat Commun. 2020. PMID: 32193378 Free PMC article. Clinical Trial.
Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns.
Watson EV, Lee JJ, Gulhan DC, Melloni GEM, Venev SV, Magesh RY, Frederick A, Chiba K, Wooten EC, Naxerova K, Dekker J, Park PJ, Elledge SJ. Watson EV, et al. Among authors: gulhan dc. Nat Genet. 2024 May;56(5):900-912. doi: 10.1038/s41588-024-01665-2. Epub 2024 Feb 22. Nat Genet. 2024. PMID: 38388848 Free PMC article.
Myeloid cell networks govern re-establishment of original immune landscapes in recurrent ovarian cancer.
Ghisoni E, Benedetti F, Minasyan A, Desbuisson M, Cunnea P, Grimm AJ, Fahr N, Capt C, Rayroux N, De Carlo F, Gulhan DC, Dagher J, Barras D, Morotti M, Marín-Jiménez JA, Chap BS, Santoro T, Spagnol G, Fleury M, Fortis K, Dorier J, Townsend MK, Tissot S, Rusakiewicz S, Ferreira HJ, Kraemer AI, Bassani-Stenberg M, Swisher EM, Kandalaft LA, Mastroyannis SA, Montone KT, Powell DJ Jr, Banerjee S, Terry KL, Tworoger SS, Pittet MJ, Tanyi JL, Coukos G, Merritt MA, Fotopoulou C, Conejo-Garcia JR, Laniti DD. Ghisoni E, et al. Among authors: gulhan dc. Cancer Cell. 2025 Aug 11;43(8):1568-1586.e10. doi: 10.1016/j.ccell.2025.07.005. Epub 2025 Jul 31. Cancer Cell. 2025. PMID: 40749672 Free article.
The E3 ligase HECTD4 regulates COX-2-dependent tumor progression and metastasis.
Vuille JA, Tanriover C, Antmen E, Micalizzi DS, Ebright RY, Animesh S, Morris R, Hajizadeh S, Nicholson ZJ, Russell HC, Zaniewski EF, Wittner BS, Wesley BK, Kwak JE, Grünewald J, Szalay RN, Fox DB, Yang M, Joung JK, Gulhan DC, Elia AEH, Haas W, Oh E, Maheswaran S, Haber DA. Vuille JA, et al. Among authors: gulhan dc. Proc Natl Acad Sci U S A. 2025 Aug 12;122(32):e2425621122. doi: 10.1073/pnas.2425621122. Epub 2025 Aug 6. Proc Natl Acad Sci U S A. 2025. PMID: 40768362 Free PMC article.
Computational analysis of cancer genome sequencing data.
Cortés-Ciriano I, Gulhan DC, Lee JJ, Melloni GEM, Park PJ. Cortés-Ciriano I, et al. Among authors: gulhan dc. Nat Rev Genet. 2022 May;23(5):298-314. doi: 10.1038/s41576-021-00431-y. Epub 2021 Dec 8. Nat Rev Genet. 2022. PMID: 34880424 Review.
Hepatic zonation determines tumorigenic potential of mutant β-catenin.
Raven A, Gilroy K, Jin H, Waldron JA, Leslie H, Munro J, Hall H, Ridgway RA, Ford CA, Gulhan DC, Vlahov N, Mills ML, Hartley A, Anderson E, Bryson S, Sphyris N, Müller M, May S, Cadden B, Nixon C, Waddell SH, Guest R, Boulter L, Barker N, Clevers H, Zhu H, Ivaska J, Strathdee D, Miller CJ, Jamieson NB, Bushell M, Park PJ, Bird TG, Sansom OJ. Raven A, et al. Among authors: gulhan dc. Nature. 2025 Nov 19. doi: 10.1038/s41586-025-09733-1. Online ahead of print. Nature. 2025. PMID: 41261129
A panel-based mutational signature of homologous recombination deficiency associates with response to PARP inhibition in metastatic castration-resistant prostate cancer.
Boiarsky D, Tewari AK, Gulhan DC, Bakouny Z, Ananda G, Savignano H, Lakshminarayanan G, McClure HM, Silver R, Choueiri TK, Taplin ME, Park PJ, Berchuck JE. Boiarsky D, et al. Among authors: gulhan dc. Prostate. 2024 Dec;84(16):1479-1489. doi: 10.1002/pros.24788. Epub 2024 Sep 9. Prostate. 2024. PMID: 39252459
29 results