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31 results

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Page 1
T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection.
Musvosvi M, Huang H, Wang C, Xia Q, Rozot V, Krishnan A, Acs P, Cheruku A, Obermoser G, Leslie A, Behar SM, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Walzl G, Hatherill M, Davis MM, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium. Musvosvi M, et al. Nat Med. 2023 Jan;29(1):258-269. doi: 10.1038/s41591-022-02110-9. Epub 2023 Jan 5. Nat Med. 2023. PMID: 36604540 Free PMC article.
Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Fails to Reverse Myeloid-Derived Suppressor Cell-Mediated T Cell Suppression in Cells Isolated From Tuberculosis Patients.
Leukes VN, Malherbe ST, Hiemstra A, Kotze LA, Roos K, Keyser A, De Swardt D, Gutschmidt A, Walzl G, du Plessis N. Leukes VN, et al. Among authors: gutschmidt a. Front Immunol. 2022 Jul 22;13:883886. doi: 10.3389/fimmu.2022.883886. eCollection 2022. Front Immunol. 2022. PMID: 35935981 Free PMC article.
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response.
Penn-Nicholson A, Mbandi SK, Thompson E, Mendelsohn SC, Suliman S, Chegou NN, Malherbe ST, Darboe F, Erasmus M, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Winter J, Murphy M, Wood R, Morrow C, Van Rhijn I, Moody B, Murray M, Andrade BB, Sterling TR, Sutherland J, Naidoo K, Padayatchi N, Walzl G, Hatherill M, Zak D, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium; SATVI Clinical and Laboratory Team; ScreenTB Consortium; AE-TBC Consortium; RePORT Brazil Team; Peruvian Household Contacts Cohort Team; CAPRISA IMPRESS team. Penn-Nicholson A, et al. Sci Rep. 2020 May 25;10(1):8629. doi: 10.1038/s41598-020-65043-8. Sci Rep. 2020. PMID: 32451443 Free PMC article.
ER-associated RNA silencing promotes ER quality control.
Efstathiou S, Ottens F, Schütter LS, Ravanelli S, Charmpilas N, Gutschmidt A, Le Pen J, Gehring NH, Miska EA, Bouças J, Hoppe T. Efstathiou S, et al. Among authors: gutschmidt a. Nat Cell Biol. 2022 Dec;24(12):1714-1725. doi: 10.1038/s41556-022-01025-4. Epub 2022 Dec 5. Nat Cell Biol. 2022. PMID: 36471127 Free PMC article.
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.
Penn-Nicholson A, Hraha T, Thompson EG, Sterling D, Mbandi SK, Wall KM, Fisher M, Suliman S, Shankar S, Hanekom WA, Janjic N, Hatherill M, Kaufmann SHE, Sutherland J, Walzl G, De Groote MA, Ochsner U, Zak DE, Scriba TJ; ACS and GC6–74 cohort study groups. Penn-Nicholson A, et al. PLoS Med. 2019 Apr 16;16(4):e1002781. doi: 10.1371/journal.pmed.1002781. eCollection 2019 Apr. PLoS Med. 2019. PMID: 30990820 Free PMC article.
Immune, metabolic, anatomical, and functional features of people after successful tuberculosis treatment: an exploratory analysis.
Webber T, Macdonald C, Tameris M, Tredoux N, Bierman A, Gutschmidt A, Tönsing S, Hiemstra A, Noor F, Snyders C, Richardson T, Fransman B, Allwood B, Hatherill M, Kleynhans L, Loxton AG, Walzl G, Chegou N, du Plessis N, Shaw JA, Malherbe ST. Webber T, et al. Among authors: gutschmidt a. Sci Rep. 2025 May 26;15(1):18392. doi: 10.1038/s41598-025-01656-1. Sci Rep. 2025. PMID: 40419526 Free PMC article.
Safety and immunogenicity of VPM1002 versus BCG in South African newborn babies: a randomised, phase 2 non-inferiority double-blind controlled trial.
Cotton MF, Madhi SA, Luabeya AK, Tameris M, Hesseling AC, Shenje J, Schoeman E, Hatherill M, Desai S, Kapse D, Brückner S, Koen A, Jose L, Moultrie A, Bhikha S, Walzl G, Gutschmidt A, Kotze LA, Allies DL, Loxton AG, Shaligram U, Abraham M, Johnstone H, Grode L, Kaufmann SHE, Kulkarni PS. Cotton MF, et al. Among authors: gutschmidt a. Lancet Infect Dis. 2022 Oct;22(10):1472-1483. doi: 10.1016/S1473-3099(22)00222-5. Epub 2022 Jun 27. Lancet Infect Dis. 2022. PMID: 35772447 Clinical Trial.
31 results