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Page 1
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.
Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Hangauer MJ, et al. Nature. 2017 Nov 9;551(7679):247-250. doi: 10.1038/nature24297. Epub 2017 Nov 1. Nature. 2017. PMID: 29088702 Free PMC article.
Integrative analysis of 111 reference human epigenomes.
Roadmap Epigenomics Consortium; Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M. Roadmap Epigenomics Consortium, et al. Nature. 2015 Feb 19;518(7539):317-30. doi: 10.1038/nature14248. Nature. 2015. PMID: 25693563 Free PMC article.
Pan-RAF:MEK Molecular Glues Take Center Stage.
Hangauer MJ, Gutkind JS, Ferguson FM. Hangauer MJ, et al. Cancer Discov. 2024 Jul 1;14(7):1143-1144. doi: 10.1158/2159-8290.CD-24-0539. Cancer Discov. 2024. PMID: 38946324
Antigenic cancer persister cells survive direct T cell attack.
Wang MX, Mauch BE, Williams AF, Barazande-Pour T, Araujo Hoffmann F, Harris SH, Lathrop CP, Turkal CE, Yung BS, Paw MH, Gervasio DAG, Tran T, Stuhlfire AE, Guo T, Daniels GA, Park SJ, Gutkind JS, Hangauer MJ. Wang MX, et al. Among authors: hangauer mj. bioRxiv [Preprint]. 2025 Mar 17:2025.03.14.643359. doi: 10.1101/2025.03.14.643359. bioRxiv. 2025. PMID: 40166148 Free PMC article. Preprint.
Drug Resistance to EGFR Inhibitors in Lung Cancer.
Tetsu O, Hangauer MJ, Phuchareon J, Eisele DW, McCormick F. Tetsu O, et al. Among authors: hangauer mj. Chemotherapy. 2016;61(5):223-35. doi: 10.1159/000443368. Epub 2016 Feb 25. Chemotherapy. 2016. PMID: 26910730 Free PMC article. Review.
Epigenetic and transcriptional determinants of the human breast.
Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, Delaney A, Tam A, Kamoh B, Cho S, Griffith M, Chu A, Robertson G, Cheung D, Li I, Heravi-Moussavi A, Moksa M, Mingay M, Hussainkhel A, Davis B, Nagarajan RP, Hong C, Echipare L, O'Geen H, Hangauer MJ, Cheng JB, Neel D, Hu D, McManus MT, Moore R, Mungall A, Ma Y, Plettner P, Ziv E, Wang T, Farnham PJ, Jones SJ, Marra MA, Tlsty TD, Costello JF, Hirst M. Gascard P, et al. Among authors: hangauer mj. Nat Commun. 2015 Feb 18;6:6351. doi: 10.1038/ncomms7351. Nat Commun. 2015. PMID: 25690954 Free PMC article.
FSP1 and histone deacetylases suppress cancer persister cell ferroptosis.
Higuchi M, Williams AF, Stuhlfire AE, Nguyen AH, Gervasio DAG, Turkal CE, Chon S, Hangauer MJ. Higuchi M, et al. Among authors: hangauer mj. bioRxiv [Preprint]. 2025 Aug 25:2025.08.21.671520. doi: 10.1101/2025.08.21.671520. bioRxiv. 2025. PMID: 40909720 Free PMC article. Preprint.
DFFB suppresses interferon to enable cancer persister cell regrowth.
Williams AF, Gervasio DAG, Turkal CE, Stuhlfire AE, Wang MX, Mauch BE, Plawat R, Nguyen AH, Paw MH, Hairani M, Lathrop CP, Harris SH, Page JL, Hangauer MJ. Williams AF, et al. Among authors: hangauer mj. bioRxiv [Preprint]. 2025 Aug 21:2025.08.15.670603. doi: 10.1101/2025.08.15.670603. bioRxiv. 2025. PMID: 40894800 Free PMC article. Preprint.
24 results