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Development and Evaluation of a Simulation-Based Algorithm to Optimize the Planning of Interim Analyses for Clinical Trials in ALS.
van Unnik JWJ, Nikolakopoulos S, Eijkemans MJC, Gonzalez-Bermejo J, Bruneteau G, Morelot-Panzini C, van den Berg LH, Cudkowicz ME, McDermott CJ, Similowski T, van Eijk RPA; DiPALS, RespiStimALS and Ceftriaxone Study Group. van Unnik JWJ, et al. Neurology. 2023 Jun 6;100(23):e2398-e2408. doi: 10.1212/WNL.0000000000207306. Epub 2023 Apr 21. Neurology. 2023. PMID: 37085329 Free PMC article.