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Intercostal or Paravertebral Block vs Thoracic Epidural in Lung Surgery: A Randomized Noninferiority Trial.
Spaans LN, Dijkgraaf MGW, Susa D, de Loos ER, Mourisse JMJ, Bouwman RA, Verhagen AFTM, van den Broek FJC; OPtriAL Study Group; Meijer P, Kuut M, Hanneman N, Bousema J, Franssen A, Brokx H, van Duyn E, Potters JW, van den Broek R, van Brakel T, Rijna H, Boom A, Noyez V, Hendriks JMH, Yogeswaran SK, Dickhoff C, van Dorp M. Spaans LN, et al. Among authors: hanneman n. JAMA Surg. 2025 Aug 1;160(8):855-864. doi: 10.1001/jamasurg.2025.1899. JAMA Surg. 2025. PMID: 40560556 Clinical Trial.
Two-year survival and disease recurrence after endosonography with or without confirmatory mediastinoscopy for resectable lung cancer (a short communication of the MEDIASTrial follow-up).
Bousema JE, Spaans LN, Dijkgraaf MGW, van der Heijden EHFM, Verhagen AFTM, Annema JT, van den Broek FJC; MEDIASTrial study group. Bousema JE, et al. Lung Cancer. 2025 Apr;202:108462. doi: 10.1016/j.lungcan.2025.108462. Epub 2025 Mar 22. Lung Cancer. 2025. PMID: 40147400 Free article. Clinical Trial.
Optimal postoperative pain management after VATS lung resection by thoracic epidural analgesia, continuous paravertebral block or single-shot intercostal nerve block (OPtriAL): study protocol of a three-arm multicentre randomised controlled trial.
Spaans LN, Dijkgraaf MGW, Meijer P, Mourisse J, Bouwman RA, Verhagen AFTM, van den Broek FJC; OPtriAL study group. Spaans LN, et al. BMC Surg. 2022 Sep 4;22(1):330. doi: 10.1186/s12893-022-01765-y. BMC Surg. 2022. PMID: 36058900 Free PMC article.