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807 results

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Page 1
Showing results for hela np
Search for Held NP instead (1 results)
Bunyavirus SFTSV nucleoprotein exploits TUFM-mediated mitophagy to impair antiviral innate immunity.
Zhang WK, Yan JM, Chu M, Li B, Gu XL, Jiang ZZ, Li ZM, Liu PP, Yu TM, Zhou CM, Yu XJ. Zhang WK, et al. Autophagy. 2025 Jan;21(1):102-119. doi: 10.1080/15548627.2024.2393067. Epub 2024 Sep 12. Autophagy. 2025. PMID: 39189526 Free PMC article.
We previously found that SFTSV nucleoprotein (NP) induces macroautophagy/autophagy to facilitate virus replication. However, the role of NP in antagonizing host innate immunity remains unclear. ...Mechanistically, SFTSV NP translocates to mitochondria by inte …
We previously found that SFTSV nucleoprotein (NP) induces macroautophagy/autophagy to facilitate virus replication. However, the role …
Peptide antisense nanoparticles.
Patel PC, Giljohann DA, Seferos DS, Mirkin CA. Patel PC, et al. Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17222-6. doi: 10.1073/pnas.0801609105. Proc Natl Acad Sci U S A. 2008. PMID: 19004812 Free PMC article.
We have designed a heterofunctionalized nanoparticle conjugate consisting of a 13-nm gold nanoparticle (Au NP) containing both antisense oligonucleotides and synthetic peptides. The synthesis of this conjugate is accomplished by mixing thiolated oligonucleotides and cystei …
We have designed a heterofunctionalized nanoparticle conjugate consisting of a 13-nm gold nanoparticle (Au NP) containing both antise …
Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10.
Yokoyama T, Yukuhiro M, Iwasaki Y, Tanaka C, Sankoda K, Fujiwara R, Shibuta A, Higashi T, Motoyama K, Arima H, Yoshida K, Sugimoto N, Morimoto H, Kosako H, Ohshima T, Fujita M. Yokoyama T, et al. Sci Rep. 2019 Nov 14;9(1):16825. doi: 10.1038/s41598-019-53259-2. Sci Rep. 2019. PMID: 31727981 Free PMC article.
Here, we identified NP-10-interacting proteins by affinity purification from HeLa cell lysates using NP-10-immobilized beads followed by mass spectrometry. ...Because NP-10 did not show antitumor activity in vivo in a previous study, we synthesized 19 …
Here, we identified NP-10-interacting proteins by affinity purification from HeLa cell lysates using NP-10-immobilized …
Development of QTMP: A promising anticancer agent through NP-Privileged Motif-Driven structural modulation.
Giri P, Batra PJ, Kumari A, Hura N, Adhikary R, Acharya A, Guchhait SK, Panda D. Giri P, et al. Bioorg Med Chem. 2023 Nov 15;95:117489. doi: 10.1016/j.bmc.2023.117489. Epub 2023 Oct 5. Bioorg Med Chem. 2023. PMID: 37816266
In this study of creating new molecules from clinical trial agents, an approach of Combretastatin structural modulation with the installation of NP-privileged motifs was considered, and a series of trimethoxyphenyl-2-aminoimidazole with functionalized quinolines and isoqui …
In this study of creating new molecules from clinical trial agents, an approach of Combretastatin structural modulation with the installatio …
Interaction between nucleocapsid protein (NP) and phosphoprotein (P) of human parainfluenza virus type 2: one of the two NP binding sites on P is essential for granule formation.
Nishio M, Tsurudome M, Kawano M, Watanabe N, Ohgimoto S, Ito M, Komada H, Ito Y. Nishio M, et al. J Gen Virol. 1996 Oct;77 ( Pt 10):2457-63. doi: 10.1099/0022-1317-77-10-2457. J Gen Virol. 1996. PMID: 8887478
The paramyxovirus phospho- (P) and nucleocapsid (NP) proteins are involved in transcription and replication of the viral genome. To study the interaction between NP and P proteins, we established HeLa cell lines that constitutively expressed the NP and …
The paramyxovirus phospho- (P) and nucleocapsid (NP) proteins are involved in transcription and replication of the viral genome. To s …
The Effect of Tryptophan-to-Tyrosine Mutation at Position 61 of the Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Virus on Viral Replication through Autophagosome Modulation.
Park JY, Senevirathne A, Lloren KKS, Lee JH. Park JY, et al. Int J Mol Sci. 2024 Jun 10;25(12):6394. doi: 10.3390/ijms25126394. Int J Mol Sci. 2024. PMID: 38928101 Free PMC article.
Initially, we examined the impact of NP expression levels, a marker for replication, upon the infection of HeLa cells with severe fever thrombocytopenia syndrome virus (SFTSV), with or without the inhibition of NP binding. Western blot analysis revealed a red …
Initially, we examined the impact of NP expression levels, a marker for replication, upon the infection of HeLa cells with sev …
The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.
Nomoto A, Lee YF, Wimmer E. Nomoto A, et al. Proc Natl Acad Sci U S A. 1976 Feb;73(2):375-80. doi: 10.1073/pnas.73.2.375. Proc Natl Acad Sci U S A. 1976. PMID: 174106 Free PMC article.
Digestion of the viral [32P]mRNA with RNase T2 and separation of the products by ion exchange chromatography at pH 5 yielded pUp as possible 5' terminus but no "capping group" of the structure m7G(5')ppp(5')Np. Total cytoplasmic [32P]RNA of HeLa cells, on the other …
Digestion of the viral [32P]mRNA with RNase T2 and separation of the products by ion exchange chromatography at pH 5 yielded pUp as possible …
Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel.
Xu L, Li X, Takemura T, Hanagata N, Wu G, Chou LL. Xu L, et al. J Nanobiotechnology. 2012 May 1;10:16. doi: 10.1186/1477-3155-10-16. J Nanobiotechnology. 2012. PMID: 22548743 Free PMC article.
BACKGROUND: Since silver-nanoparticles (NPs) possess an antibacterial activity, they were commonly used in medical products and devices, food storage materials, cosmetics, various health care products, and industrial products. Various silver-NP based medical devices are av …
BACKGROUND: Since silver-nanoparticles (NPs) possess an antibacterial activity, they were commonly used in medical products and devices, foo …
Bougainvinones NP, three new flavonoids from Bougainvillea spectabilis.
Nguyen TTA, Nguyen HL, Pham TNK, Nguyen PKP, Huynh TTN, Sichaem J, Do LTM. Nguyen TTA, et al. Fitoterapia. 2021 Mar;149:104832. doi: 10.1016/j.fitote.2021.104832. Epub 2021 Jan 16. Fitoterapia. 2021. PMID: 33460723
The structures of these compounds were accomplished using comprehensive spectroscopic methods, including 1D and 2D NMR spectra with references to the literatures, as well as high-resolution mass spectrometric analysis. Their cytotoxicity against KB and HeLa S-3 cell lines …
The structures of these compounds were accomplished using comprehensive spectroscopic methods, including 1D and 2D NMR spectra with referenc …
Autofluorescence-Free Live-Cell Imaging Using Terbium Nanoparticles.
Cardoso Dos Santos M, Goetz J, Bartenlian H, Wong KL, Charbonnière LJ, Hildebrandt N. Cardoso Dos Santos M, et al. Bioconjug Chem. 2018 Apr 18;29(4):1327-1334. doi: 10.1021/acs.bioconjchem.8b00069. Epub 2018 Feb 26. Bioconjug Chem. 2018. PMID: 29461805
Here, we show the application of a new type of surface-photosensitized terbium NPs (Tb-NPs) for autofluorescence-free intracellular imaging in live HeLa cells. The combination of exceptionally high brightness, high photostability, and long photoluminecence (PL) lifetimes f …
Here, we show the application of a new type of surface-photosensitized terbium NPs (Tb-NPs) for autofluorescence-free intracellular imaging …
807 results