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Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture.
Major Extremity Trauma Research Consortium (METRC); O'Toole RV, Stein DM, O'Hara NN, Frey KP, Taylor TJ, Scharfstein DO, Carlini AR, Sudini K, Degani Y, Slobogean GP, Haut ER, Obremskey W, Firoozabadi R, Bosse MJ, Goldhaber SZ, Marvel D, Castillo RC. Major Extremity Trauma Research Consortium (METRC), et al. N Engl J Med. 2023 Jan 19;388(3):203-213. doi: 10.1056/NEJMoa2205973. N Engl J Med. 2023. PMID: 36652352 Clinical Trial.
Risk-stratified thromboprophylaxis effects of aspirin versus low-molecular-weight heparin in orthopedic trauma patients: A secondary analysis of the PREVENT CLOT trial.
O'Hara NN, O'Toole RV, Frey KP, Castillo RC, Cuschieri J, Haut ER, Slobogean GP, Firoozabadi R, Christmas AB, Obremskey WT, Carlini AR, Gaski GE, Kutcher ME, Marvel D, Stein DM; Major Extremity Trauma Research Consortium (METRC). O'Hara NN, et al. J Trauma Acute Care Surg. 2024 Apr 1;96(4):573-582. doi: 10.1097/TA.0000000000004226. Epub 2023 Dec 8. J Trauma Acute Care Surg. 2024. PMID: 38079260
Cost Savings of Switching to Aspirin for Thromboprophylaxis in Orthopaedic Trauma Patients: A Budget Impact Analysis.
Levy JF, O'Toole RV, Stein DM, Haut ER, Frey KP, Castillo RC, O'Hara NN; METRC; Major Extremity Trauma Research Consortium (METRC) Corporate Author; METRC and Major Extremity Trauma Research Consortium (METRC) Corporate Author. Levy JF, et al. J Am Acad Orthop Surg. 2025 Jul 9. doi: 10.5435/JAAOS-D-24-01331. Online ahead of print. J Am Acad Orthop Surg. 2025. PMID: 40668732