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1866 1
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1874 2
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1916 1
1929 1
1931 2
1939 1
1942 1
1945 3
1947 1
1948 14
1949 11
1950 8
1951 4
1952 11
1953 7
1954 5
1955 5
1956 6
1957 11
1958 17
1959 11
1960 11
1961 11
1962 36
1963 37
1964 49
1965 57
1966 38
1967 47
1968 34
1969 51
1970 78
1971 93
1972 111
1973 116
1974 116
1975 172
1976 185
1977 194
1978 195
1979 241
1980 275
1981 249
1982 253
1983 294
1984 326
1985 370
1986 415
1987 460
1988 555
1989 586
1990 577
1991 589
1992 670
1993 732
1994 790
1995 908
1996 1053
1997 1055
1998 1100
1999 1326
2000 1524
2001 1751
2002 1917
2003 2112
2004 2278
2005 2655
2006 2879
2007 3268
2008 5044
2009 5985
2010 6466
2011 6920
2012 7062
2013 6179
2014 6174
2015 6601
2016 6241
2017 6934
2018 7642
2019 8585
2020 10500
2021 11873
2022 11735
2023 11099
2024 11695
2025 11740
2026 70

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164,518 results

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Page 1
HO-1 overexpression and underexpression: Clinical implications.
Drummond GS, Baum J, Greenberg M, Lewis D, Abraham NG. Drummond GS, et al. Arch Biochem Biophys. 2019 Sep 30;673:108073. doi: 10.1016/j.abb.2019.108073. Epub 2019 Aug 16. Arch Biochem Biophys. 2019. PMID: 31425676 Free PMC article. Review.
In this review we examine the effects of both over- and under-production of heme oxygenase-1 (HO-1) and HO activity on a broad spectrum of biological systems and on vascular disease. In a few instances e.g., neonatal jaundice, overproduction of HO-1 and incre …
In this review we examine the effects of both over- and under-production of heme oxygenase-1 (HO-1) and HO activity on a broad …
Heterotopic ossification (HO) prophylaxis after distal biceps repair.
Dave U, Mosalakanti J, Guduri P, Rumps M, Mulcahey MK. Dave U, et al. JSES Rev Rep Tech. 2024 Jun 17;4(4):715-719. doi: 10.1016/j.xrrt.2024.05.012. eCollection 2024 Nov. JSES Rev Rep Tech. 2024. PMID: 39474166 Free PMC article. Review.
Studies were included if they compared patients who were placed on HO prophylaxis following distal biceps repair compared to those that were not placed on HO prophylaxis, were prospective randomized controlled trials or retrospective case-control studies, and evalua …
Studies were included if they compared patients who were placed on HO prophylaxis following distal biceps repair compared to those th …
Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.
Intagliata S, Salerno L, Ciaffaglione V, Leonardi C, Fallica AN, Carota G, Amata E, Marrazzo A, Pittalà V, Romeo G. Intagliata S, et al. Eur J Med Chem. 2019 Dec 1;183:111703. doi: 10.1016/j.ejmech.2019.111703. Epub 2019 Sep 17. Eur J Med Chem. 2019. PMID: 31550661 Review.
Heme oxygenase (HO) enzymes are involved in heme catabolism and several physiological functions. Among the different HO isoforms, HO-2 stands out for its neuroprotective properties and modulatory activity in male reproduction. ...To the best of our knowledge, …
Heme oxygenase (HO) enzymes are involved in heme catabolism and several physiological functions. Among the different HO isofor …
HO in pregnancy.
Bainbridge SA, Smith GN. Bainbridge SA, et al. Free Radic Biol Med. 2005 Apr 15;38(8):979-88. doi: 10.1016/j.freeradbiomed.2004.11.002. Free Radic Biol Med. 2005. PMID: 15780756 Review.
Included in this new wave of interest is the involvement of HO, and its by-products, in the normal function of the vital organ of pregnancy, the placenta. In this review the role of HO, and its catalytic products, will be examined in the context of pregnancy. The di …
Included in this new wave of interest is the involvement of HO, and its by-products, in the normal function of the vital organ of pre …
HO-1: a new marker for predicting postoperative recurrence of CRSwNP.
Gong MJ, Wang YS, Lou M, Ma RP, Hu ZZ, Zheng GX, Zhang Y. Gong MJ, et al. Acta Otolaryngol. 2023 Feb;143(2):170-175. doi: 10.1080/00016489.2023.2168054. Epub 2023 Jan 27. Acta Otolaryngol. 2023. PMID: 36705254
We use Immunohistochemical staining to determine the expression of HO-1 in tissues. We use Spearman correlation test to analyze the correlation between HO-1 positive cell count and clinical score, and ROC curve to assess the value of HO-1 positive cell count …
We use Immunohistochemical staining to determine the expression of HO-1 in tissues. We use Spearman correlation test to analyze the c …
Upregulation of hemeoxygenase enzymes HO-1 and HO-2 following ischemia-reperfusion injury in connection with experimental cardiac arrest and cardiopulmonary resuscitation: Neuroprotective effects of methylene blue.
Wiklund L, Sharma A, Patnaik R, Muresanu DF, Sahib S, Tian ZR, Castellani RJ, Nozari A, Lafuente JV, Sharma HS. Wiklund L, et al. Prog Brain Res. 2021;265:317-375. doi: 10.1016/bs.pbr.2021.06.009. Epub 2021 Aug 12. Prog Brain Res. 2021. PMID: 34560924 Review.
Increased production of carbon monoxide (CO) by the enzyme hemeoxygenase (HO) in the brain is induced by the oxidative stress. HO is present in the CNS in two isoforms, namely the inducible HO-1 and the constitutive HO-2. Elevated levels of serum HO …
Increased production of carbon monoxide (CO) by the enzyme hemeoxygenase (HO) in the brain is induced by the oxidative stress. HO …
Heme-Oxygenase-1.
Facchinetti MM. Facchinetti MM. Antioxid Redox Signal. 2020 Jun 10;32(17):1239-1242. doi: 10.1089/ars.2020.8065. Antioxid Redox Signal. 2020. PMID: 32148070
This Forum issue "Heme Oxygenase" (HO) includes original research articles and reviews that are aimed at understanding the role of HO-1 in several pathophysiological conditions, specially addressing those involving inflammation and oxidative damage. ...Contrariwise, …
This Forum issue "Heme Oxygenase" (HO) includes original research articles and reviews that are aimed at understanding the role of …
Constitutive HO-1 and CD55 (DAF) Expression and Regulatory Interaction in Cultured Podocytes.
Lianos EA, Wilson K, Goudevenou K, Detsika MG, Sharma M. Lianos EA, et al. Biomedicines. 2023 Dec 13;11(12):3297. doi: 10.3390/biomedicines11123297. Biomedicines. 2023. PMID: 38137516 Free PMC article.
In this preliminary study, we assessed whether constitutively expressed HO-1 regulates CD55 expression in cultured rat podocytes. We employed methods of flow cytometry, quantitative (q) RT-qPCR and post-transcriptional HO-1 gene silencing (HO-1 interfering RN …
In this preliminary study, we assessed whether constitutively expressed HO-1 regulates CD55 expression in cultured rat podocytes. We …
HO-1 Protects Remnant Liver against Dysfunction after Major Hepatectomy in Humans.
He N, Sun X, Hu Z, Wang F, Zhang Y, Chen X, Wu H, Zhou X, Zheng S, Jin X. He N, et al. J Invest Surg. 2022 May;35(5):1163-1169. doi: 10.1080/08941939.2021.1980837. Epub 2021 Oct 15. J Invest Surg. 2022. PMID: 34651541 Free article.
Preoperative HO-1 specifically predicted LD during the first week after surgery (AUC: 0.757; P = 0.01). ...And HO-1 was an independent predictor for poor clinical outcome. CONCLUSIONS: We had provided the first clinical data verifying that human HO-1 was rela …
Preoperative HO-1 specifically predicted LD during the first week after surgery (AUC: 0.757; P = 0.01). ...And HO-1 was an ind …
HO-3867 Induces Apoptosis via the JNK Signaling Pathway in Human Osteosarcoma Cells.
Lu PW, Chou CH, Yang JS, Hsieh YH, Tsai MY, Lu KH, Yang SF. Lu PW, et al. Pharmaceutics. 2022 Jun 13;14(6):1257. doi: 10.3390/pharmaceutics14061257. Pharmaceutics. 2022. PMID: 35745828 Free PMC article.
After observing the decrease in cellular viability of three human osteosarcoma U2OS, HOS, and MG-63 cell lines, and the induction of cellular apoptosis and arrest in sub-G1 phase in U2OS and HOS cells by HO-3867, the human apoptosis array showed that heme oxygenase (HO …
After observing the decrease in cellular viability of three human osteosarcoma U2OS, HOS, and MG-63 cell lines, and the induction of cellula …
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