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Page 1
Variant Interpretation for Dilated Cardiomyopathy: Refinement of the American College of Medical Genetics and Genomics/ClinGen Guidelines for the DCM Precision Medicine Study.
Morales A, Kinnamon DD, Jordan E, Platt J, Vatta M, Dorschner MO, Starkey CA, Mead JO, Ai T, Burke W, Gastier-Foster J, Jarvik GP, Rehm HL, Nickerson DA, Hershberger RE; DCM Precision Medicine study of the DCM Consortium; DCM Consortium institutions and personnel participating in this study: Study Principal Investigator and Co-Investigators,DCM Consortium Clinical Site Principal Investigators and Clinical Site Other Significant Contributors (OSC). The following clinical sites and individuals contributed to the submission of RO 1 H L 128857 as Site Principal Investigators (Site Pl) or as Other Significant Contributors (OSC),Dr. Huggins also served as study co-principal investigator,The following clinical site was added following approval of NHGRI supplemental funding but prior to initiation of enrollment,The following clinical sites were added following study activation. Morales A, et al. Circ Genom Precis Med. 2020 Apr;13(2):e002480. doi: 10.1161/CIRCGEN.119.002480. Epub 2020 Mar 11. Circ Genom Precis Med. 2020. PMID: 32160020 Free PMC article.
Rare Variant Genetics and Dilated Cardiomyopathy Severity: The DCM Precision Medicine Study.
Hofmeyer M, Haas GJ, Jordan E, Cao J, Kransdorf E, Ewald GA, Morris AA, Owens A, Lowes B, Stoller D, Wilson Tang WH, Garg S, Trachtenberg BH, Shah P, Pamboukian SV, Sweitzer NK, Wheeler MT, Wilcox JE, Katz S, Pan S, Jimenez J, Smart F, Wang J, Gottlieb SS, Judge DP, Moore CK, Huggins GS, Kinnamon DD, Ni H, Hershberger RE; DCM Precision Medicine Study of the DCM Consortium. Hofmeyer M, et al. Circulation. 2023 Sep 12;148(11):872-881. doi: 10.1161/CIRCULATIONAHA.123.064847. Epub 2023 Aug 29. Circulation. 2023. PMID: 37641966 Free PMC article. Clinical Trial.
Genetic Architecture of Dilated Cardiomyopathy in Individuals of African and European Ancestry.
Jordan E, Kinnamon DD, Haas GJ, Hofmeyer M, Kransdorf E, Ewald GA, Morris AA, Owens A, Lowes B, Stoller D, Tang WHW, Garg S, Trachtenberg BH, Shah P, Pamboukian SV, Sweitzer NK, Wheeler MT, Wilcox JE, Katz S, Pan S, Jimenez J, Fishbein DP, Smart F, Wang J, Gottlieb SS, Judge DP, Moore CK, Mead JO, Hurst N, Cao J, Huggins GS, Cowan J, Ni H, Rehm HL, Jarvik GP, Vatta M, Burke W, Hershberger RE; DCM Precision Medicine Study of the DCM Consortium. Jordan E, et al. Among authors: hofmeyer m. JAMA. 2023 Aug 1;330(5):432-441. doi: 10.1001/jama.2023.11970. JAMA. 2023. PMID: 37526719 Free PMC article.
REALM-DCM: A Phase 3, Multinational, Randomized, Placebo-Controlled Trial of ARRY-371797 in Patients With Symptomatic LMNA-Related Dilated Cardiomyopathy.
Garcia-Pavia P, Palomares JFR, Sinagra G, Barriales-Villa R, Lakdawala NK, Gottlieb RL, Goldberg RI, Elliott P, Lee P, Li H, Angeli FS, Judge DP, MacRae CA; REALM-DCM Investigators. Garcia-Pavia P, et al. Circ Heart Fail. 2024 Jul;17(7):e011548. doi: 10.1161/CIRCHEARTFAILURE.123.011548. Epub 2024 Jul 9. Circ Heart Fail. 2024. PMID: 38979608 Free PMC article. Clinical Trial.
Beta-blockers and Ambulatory Inotropic Therapy.
Zaghlol R, Ghazzal A, Radwan S, Zaghlol L, Hamad A, Chou J, Ahmed S, Hofmeyer M, Rodrigo ME, Kadakkal A, Lam PH, Rao SD, Weintraub WS, Molina EJ, Sheikh FH, Najjar SS. Zaghlol R, et al. Among authors: hofmeyer m. J Card Fail. 2022 Aug;28(8):1309-1317. doi: 10.1016/j.cardfail.2022.03.352. Epub 2022 Apr 18. J Card Fail. 2022. PMID: 35447337
Implementing Precision Medicine for Dilated Cardiomyopathy: Insights from The DCM Consortium.
Jordan E, Ni H, Parker P, Kinnamon DD, Owens A, Lowes B, Shenoy C, Martin CM, Judge DP, Fishbein DP, Stoller D, Minami E, Kransdorf E, Smart F, Haas GJ, Huggins GS, Ewald GA, Diamond J, Wilcox JE, Jimenez J, Wang J, Tallaj J, Drazner MH, Hofmeyer M, Wheeler MT, Pinzon OW, Shah P, Gottlieb SS, Katz S, Shore S, Tang WHW, Hershberger RE; DCM Precision Medicine study of the DCM Consortium. Jordan E, et al. Among authors: hofmeyer m. medRxiv [Preprint]. 2024 Nov 26:2024.11.22.24317816. doi: 10.1101/2024.11.22.24317816. medRxiv. 2024. Update in: Circ Genom Precis Med. 2025 Aug;18(4):e005078. doi: 10.1161/CIRCGEN.125.005078. PMID: 39649582 Free PMC article. Updated. Preprint.
Implementing Precision Medicine for Dilated Cardiomyopathy: Insights From the DCM Consortium.
Jordan E, Ni H, Parker P, Kinnamon DD, Owens A, Lowes B, Shenoy C, Martin CM, Judge DP, Fishbein DP, Stoller D, Minami E, Kransdorf EP, Smart F, Haas GJ, Huggins GS, Ewald GA, Diamond J, Wilcox JE, Jimenez J, Wang J, Tallaj J, Drazner MH, Hofmeyer M, Wheeler MT, Wever Pinzon O, Shah P, Gottlieb SS, Katz SD, Shore S, Tang WHW, Hershberger RE; DCM Consortium. Jordan E, et al. Among authors: hofmeyer m. Circ Genom Precis Med. 2025 Aug;18(4):e005078. doi: 10.1161/CIRCGEN.125.005078. Epub 2025 Jun 18. Circ Genom Precis Med. 2025. PMID: 40528765
Screening for Dilated Cardiomyopathy in At-Risk First-Degree Relatives.
Ni H, Jordan E, Kinnamon DD, Cao J, Haas GJ, Hofmeyer M, Kransdorf E, Ewald GA, Morris AA, Owens A, Lowes B, Stoller D, Tang WHW, Garg S, Trachtenberg BH, Shah P, Pamboukian SV, Sweitzer NK, Wheeler MT, Wilcox JE, Katz S, Pan S, Jimenez J, Fishbein DP, Smart F, Wang J, Gottlieb SS, Judge DP, Moore CK, Huggins GS, Hershberger RE; DCM Precision Medicine Study of the DCM Consortium. Ni H, et al. Among authors: hofmeyer m. J Am Coll Cardiol. 2023 May 30;81(21):2059-2071. doi: 10.1016/j.jacc.2023.03.419. J Am Coll Cardiol. 2023. PMID: 37225358 Free PMC article.
Antecedent Flu-Like Illness and Onset of Idiopathic Dilated Cardiomyopathy: The DCM Precision Medicine Study.
Ni H, Cao J, Kinnamon DD, Jordan E, Haas GJ, Hofmeyer M, Kransdorf EP, Diamond J, Owens A, Lowes B, Stoller D, Tang WHW, Drazner MH, Shah P, Wilcox JE, Katz SD, Jimenez J, Shore S, Judge DP, Mead JO, Cowan J, Parker PK, Huggins GS, Hershberger RE. Ni H, et al. Among authors: hofmeyer m. Circ Heart Fail. 2025 May;18(5):e012602. doi: 10.1161/CIRCHEARTFAILURE.124.012602. Epub 2025 Apr 14. Circ Heart Fail. 2025. PMID: 40392911
Alcohol Exposure Among Patients With Dilated Cardiomyopathy and Their First-Degree Relatives: The DCM Precision Medicine Study.
Jimenez J, Ni H, Katz SD, Haas GJ, Cao J, Rubens M, Chaparro S, Saxena A, Hofmeyer M, Kransdorf E, Ewald GA, Morris AA, Owens A, Lowes B, Stoller D, Tang WHW, Shah P, Wilcox JE, Smart F, Wang J, Gottlieb SS, Judge DP, Mead JO, Hurst N, Parker PK, Huggins GS, Jordan E, Kinnamon DD, Hershberger RE; DCM Precision Medicine Study of the DCM Consortium. Jimenez J, et al. Among authors: hofmeyer m. Circ Genom Precis Med. 2025 Apr;18(2):e004946. doi: 10.1161/CIRCGEN.124.004946. Epub 2025 Mar 28. Circ Genom Precis Med. 2025. PMID: 40151927 Clinical Trial.
34 results