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Year Number of Results
1959 1
1978 1
1979 2
1983 1
1986 3
1987 1
1989 1
1990 1
1991 2
1992 1
1993 3
1994 1
1995 2
1996 1
1997 1
1998 1
1999 2
2000 1
2001 4
2002 2
2004 3
2005 3
2006 5
2007 5
2008 2
2010 4
2011 9
2012 8
2013 5
2014 6
2015 13
2016 14
2017 8
2018 7
2019 16
2020 18
2021 20
2022 29
2023 30
2024 33
2025 18

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265 results

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Page 1
Targeting peptide antigens using a multiallelic MHC I-binding system.
Du H, Mallik L, Hwang D, Sun Y, Kaku C, Hoces D, Sun SM, Ghinnagow R, Carro SD, Phan HAT, Gupta S, Blackson W, Lee H, Choe CA, Dersh D, Liu J, Bell B, Yang H, Papadaki GF, Young MC, Zhou E, El Nesr G, Goli KD, Eisenlohr LC, Minn AJ, Hernandez-Lopez RA, Jardine JG, Sgourakis NG, Huang PS. Du H, et al. Among authors: huang ps. Nat Biotechnol. 2024 Dec 13:10.1038/s41587-024-02505-8. doi: 10.1038/s41587-024-02505-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 39672954
Computational design of transmembrane pores.
Xu C, Lu P, Gamal El-Din TM, Pei XY, Johnson MC, Uyeda A, Bick MJ, Xu Q, Jiang D, Bai H, Reggiano G, Hsia Y, Brunette TJ, Dou J, Ma D, Lynch EM, Boyken SE, Huang PS, Stewart L, DiMaio F, Kollman JM, Luisi BF, Matsuura T, Catterall WA, Baker D. Xu C, et al. Among authors: huang ps. Nature. 2020 Sep;585(7823):129-134. doi: 10.1038/s41586-020-2646-5. Epub 2020 Aug 26. Nature. 2020. PMID: 32848250 Free PMC article.
Macromolecular modeling and design in Rosetta: recent methods and frameworks.
Leman JK, Weitzner BD, Lewis SM, Adolf-Bryfogle J, Alam N, Alford RF, Aprahamian M, Baker D, Barlow KA, Barth P, Basanta B, Bender BJ, Blacklock K, Bonet J, Boyken SE, Bradley P, Bystroff C, Conway P, Cooper S, Correia BE, Coventry B, Das R, De Jong RM, DiMaio F, Dsilva L, Dunbrack R, Ford AS, Frenz B, Fu DY, Geniesse C, Goldschmidt L, Gowthaman R, Gray JJ, Gront D, Guffy S, Horowitz S, Huang PS, Huber T, Jacobs TM, Jeliazkov JR, Johnson DK, Kappel K, Karanicolas J, Khakzad H, Khar KR, Khare SD, Khatib F, Khramushin A, King IC, Kleffner R, Koepnick B, Kortemme T, Kuenze G, Kuhlman B, Kuroda D, Labonte JW, Lai JK, Lapidoth G, Leaver-Fay A, Lindert S, Linsky T, London N, Lubin JH, Lyskov S, Maguire J, Malmström L, Marcos E, Marcu O, Marze NA, Meiler J, Moretti R, Mulligan VK, Nerli S, Norn C, Ó'Conchúir S, Ollikainen N, Ovchinnikov S, Pacella MS, Pan X, Park H, Pavlovicz RE, Pethe M, Pierce BG, Pilla KB, Raveh B, Renfrew PD, Burman SSR, Rubenstein A, Sauer MF, Scheck A, Schief W, Schueler-Furman O, Sedan Y, Sevy AM, Sgourakis NG, Shi L, Siegel JB, Silva DA, Smith S, Song Y, Stein A, Szegedy M, Teets FD, Thyme SB, Wang RY, Watkins A, Zimmerman L, Bonneau R. Leman JK, et al. Among authors: huang ps. Nat Methods. 2020 Jul;17(7):665-680. doi: 10.1038/s41592-020-0848-2. Epub 2020 Jun 1. Nat Methods. 2020. PMID: 32483333 Free PMC article. Review.
A general system for targeting MHC class II-antigen complex via a single adaptable loop.
Du H, Liu J, Jude KM, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Blackson W, Mobedi A, Parekh U, Parra Sperberg RA, Julien JP, Mellins ED, Garcia KC, Huang PS. Du H, et al. Among authors: huang ps. Nat Biotechnol. 2024 Dec 13:10.1038/s41587-024-02466-y. doi: 10.1038/s41587-024-02466-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 39672953 Free PMC article.
Structure-based protein design with deep learning.
Ovchinnikov S, Huang PS. Ovchinnikov S, et al. Among authors: huang ps. Curr Opin Chem Biol. 2021 Dec;65:136-144. doi: 10.1016/j.cbpa.2021.08.004. Epub 2021 Sep 20. Curr Opin Chem Biol. 2021. PMID: 34547592 Free PMC article. Review.
Interleukin-2 superkines by computational design.
Ren J, Chu AE, Jude KM, Picton LK, Kare AJ, Su L, Montano Romero A, Huang PS, Garcia KC. Ren J, et al. Among authors: huang ps. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2117401119. doi: 10.1073/pnas.2117401119. Epub 2022 Mar 16. Proc Natl Acad Sci U S A. 2022. PMID: 35294290 Free PMC article.
Competition-level code generation with AlphaCode.
Li Y, Choi D, Chung J, Kushman N, Schrittwieser J, Leblond R, Eccles T, Keeling J, Gimeno F, Dal Lago A, Hubert T, Choy P, de Masson d'Autume C, Babuschkin I, Chen X, Huang PS, Welbl J, Gowal S, Cherepanov A, Molloy J, Mankowitz DJ, Sutherland Robson E, Kohli P, de Freitas N, Kavukcuoglu K, Vinyals O. Li Y, et al. Among authors: huang ps. Science. 2022 Dec 9;378(6624):1092-1097. doi: 10.1126/science.abq1158. Epub 2022 Dec 8. Science. 2022. PMID: 36480631
A general platform for targeting MHC-II antigens via a single loop.
Du H, Liu J, Jude KM, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Mobedi A, Parekh U, Sperberg RAP, Julien JP, Mellins ED, Garcia KC, Huang PS. Du H, et al. Among authors: huang ps. bioRxiv [Preprint]. 2024 Jan 30:2024.01.26.577489. doi: 10.1101/2024.01.26.577489. bioRxiv. 2024. PMID: 38352315 Free PMC article. Preprint.
An all-atom protein generative model.
Chu AE, Kim J, Cheng L, El Nesr G, Xu M, Shuai RW, Huang PS. Chu AE, et al. Among authors: huang ps. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2311500121. doi: 10.1073/pnas.2311500121. Epub 2024 Jun 25. Proc Natl Acad Sci U S A. 2024. PMID: 38916999 Free PMC article.
265 results