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1951 1
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46 results

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Page 1
The Translational Landscape of the Human Heart.
van Heesch S, Witte F, Schneider-Lunitz V, Schulz JF, Adami E, Faber AB, Kirchner M, Maatz H, Blachut S, Sandmann CL, Kanda M, Worth CL, Schafer S, Calviello L, Merriott R, Patone G, Hummel O, Wyler E, Obermayer B, Mücke MB, Lindberg EL, Trnka F, Memczak S, Schilling M, Felkin LE, Barton PJR, Quaife NM, Vanezis K, Diecke S, Mukai M, Mah N, Oh SJ, Kurtz A, Schramm C, Schwinge D, Sebode M, Harakalova M, Asselbergs FW, Vink A, de Weger RA, Viswanathan S, Widjaja AA, Gärtner-Rommel A, Milting H, Dos Remedios C, Knosalla C, Mertins P, Landthaler M, Vingron M, Linke WA, Seidman JG, Seidman CE, Rajewsky N, Ohler U, Cook SA, Hubner N. van Heesch S, et al. Among authors: hummel o. Cell. 2019 Jun 27;178(1):242-260.e29. doi: 10.1016/j.cell.2019.05.010. Epub 2019 May 30. Cell. 2019. PMID: 31155234 Free article.
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Ferreira MA, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, van Dongen J, Lu Y, Rüschendorf F, Esparza-Gordillo J, Medway CW, Mountjoy E, Burrows K, Hummel O, Grosche S, Brumpton BM, Witte JS, Hottenga JJ, Willemsen G, Zheng J, Rodríguez E, Hotze M, Franke A, Revez JA, Beesley J, Matheson MC, Dharmage SC, Bain LM, Fritsche LG, Gabrielsen ME, Balliu B; 23andMe Research Team; AAGC collaborators; BIOS consortium; LifeLines Cohort Study; Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Arnold A, Homuth G, Schmidt CO, Thompson PJ, Martin NG, Duffy DL, Novak N, Schulz H, Karrasch S, Gieger C, Strauch K, Melles RB, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jansen R, Jorgenson E, Lee YA, Boomsma DI, Almqvist C, Karlsson R, Koppelman GH, Paternoster L. Ferreira MA, et al. Among authors: hummel o. Nat Genet. 2017 Dec;49(12):1752-1757. doi: 10.1038/ng.3985. Epub 2017 Oct 30. Nat Genet. 2017. PMID: 29083406 Free PMC article.
PITX2 deficiency leads to atrial mitochondrial dysfunction.
Reyat JS, Sommerfeld LC, O'Reilly M, Roth Cardoso V, Thiemann E, Khan AO, O'Shea C, Harder S, Müller C, Barlow J, Stapley RJ, Chua W, Kabir SN, Grech O, Hummel O, Hübner N, Kääb S, Mont L, Hatem SN, Winters J, Zeemering S, Morgan NV, Rayes J, Gehmlich K, Stoll M, Brand T, Schweizer M, Piasecki A, Schotten U, Gkoutos GV, Lorenz K, Cuello F, Kirchhof P, Fabritz L. Reyat JS, et al. Among authors: hummel o. Cardiovasc Res. 2024 Dec 4;120(15):1907-1923. doi: 10.1093/cvr/cvae169. Cardiovasc Res. 2024. PMID: 39129206 Free PMC article.
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts.
Ruiz-Orera J, Miller DC, Greiner J, Genehr C, Grammatikaki A, Blachut S, Mbebi J, Patone G, Myronova A, Adami E, Dewani N, Liang N, Hummel O, Muecke MB, Hildebrandt TB, Fritsch G, Schrade L, Zimmermann WH, Kondova I, Diecke S, van Heesch S, Hübner N. Ruiz-Orera J, et al. Among authors: hummel o. Nat Cardiovasc Res. 2024 Oct;3(10):1217-1235. doi: 10.1038/s44161-024-00544-7. Epub 2024 Sep 24. Nat Cardiovasc Res. 2024. PMID: 39317836 Free PMC article.
Natural genetic variation quantitatively regulates heart rate and dimension.
Gierten J, Welz B, Fitzgerald T, Thumberger T, Agarwal R, Hummel O, Leger A, Weber P, Naruse K, Hassel D, Hübner N, Birney E, Wittbrodt J. Gierten J, et al. Among authors: hummel o. Nat Commun. 2025 Apr 30;16(1):4062. doi: 10.1038/s41467-025-59425-7. Nat Commun. 2025. PMID: 40307248 Free PMC article.
Phosphatidylinositol 4-kinase β mutations cause nonsyndromic sensorineural deafness and inner ear malformation.
Su X, Feng Y, Rahman SA, Wu S, Li G, Rüschendorf F, Zhao L, Cui H, Liang J, Fang L, Hu H, Froehler S, Yu Y, Patone G, Hummel O, Chen Q, Raile K, Luft FC, Bähring S, Hussain K, Chen W, Zhang J, Gong M. Su X, et al. Among authors: hummel o. J Genet Genomics. 2020 Oct 20;47(10):618-626. doi: 10.1016/j.jgg.2020.07.008. Epub 2020 Oct 28. J Genet Genomics. 2020. PMID: 33358777
Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, Chen J, Jauch R, Bogu GK, Nolden T, Himmelbauer H, Xavier Doss M, Sachinidis A, Schulz H, Hummel O, Martinelli P, Hübner N, Stanton LW, Real FX, Bourillot PY, Savatier P. Aksoy I, et al. Among authors: hummel o. Nat Commun. 2014 Apr 28;5:3719. doi: 10.1038/ncomms4719. Nat Commun. 2014. PMID: 24770696 Free article.
46 results