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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1850 1
1852 1
1855 2
1857 2
1883 4
1884 1
1889 1
1892 1
1895 1
1898 1
1899 1
1900 1
1901 2
1903 3
1904 4
1905 5
1906 1
1907 5
1908 2
1909 3
1910 3
1912 2
1913 2
1914 2
1915 6
1916 3
1917 2
1918 3
1919 1
1920 4
1921 1
1922 2
1923 2
1924 1
1925 3
1926 1
1927 4
1928 5
1929 8
1930 2
1931 2
1932 4
1933 3
1934 2
1935 7
1936 2
1937 8
1938 6
1939 1
1940 2
1941 3
1942 3
1943 3
1944 1
1945 9
1946 7
1947 8
1948 9
1949 4
1950 3
1951 8
1952 7
1953 8
1954 12
1955 13
1956 15
1957 11
1958 15
1959 15
1960 15
1961 17
1962 22
1963 21
1964 17
1965 26
1966 27
1967 42
1968 40
1969 46
1970 54
1971 62
1972 82
1973 74
1974 97
1975 74
1976 125
1977 127
1978 131
1979 124
1980 133
1981 152
1982 131
1983 158
1984 171
1985 175
1986 190
1987 211
1988 238
1989 254
1990 296
1991 278
1992 310
1993 374
1994 355
1995 371
1996 370
1997 405
1998 389
1999 467
2000 541
2001 595
2002 592
2003 629
2004 782
2005 832
2006 952
2007 966
2008 1028
2009 1006
2010 1185
2011 1348
2012 1374
2013 1481
2014 1657
2015 1814
2016 1970
2017 2064
2018 2036
2019 1947
2020 2182
2021 2313
2022 2251
2023 2057
2024 2104
2025 2035
2026 11

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40,418 results

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Page 1
Huntington's disease.
Walker FO. Walker FO. Lancet. 2007 Jan 20;369(9557):218-28. doi: 10.1016/S0140-6736(07)60111-1. Lancet. 2007. PMID: 17240289 Review.
Huntington's disease is an autosomal-dominant, progressive neurodegenerative disorder with a distinct phenotype, including chorea and dystonia, incoordination, cognitive decline, and behavioural difficulties. ...The precise pathophysiological mechanisms of Huntin …
Huntington's disease is an autosomal-dominant, progressive neurodegenerative disorder with a distinct phenotype, including cho …
Huntington's disease.
Ha AD, Fung VS. Ha AD, et al. Curr Opin Neurol. 2012 Aug;25(4):491-8. doi: 10.1097/WCO.0b013e3283550c97. Curr Opin Neurol. 2012. PMID: 22772878 Review.
PURPOSE OF REVIEW: This review highlights the recent advances in Huntington's disease, with particular focus on clinical characterization of prodromal Huntington's disease, as well as the growing literature regarding pathophysiological mechanisms and t …
PURPOSE OF REVIEW: This review highlights the recent advances in Huntington's disease, with particular focus on clinical chara …
Huntington's disease clinical trials update: March 2025.
Farag M, Tabrizi SJ, Wild EJ. Farag M, et al. J Huntingtons Dis. 2025 May;14(2):191-206. doi: 10.1177/18796397251337000. Epub 2025 Apr 30. J Huntingtons Dis. 2025. PMID: 40302443 Free PMC article. Review.
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing phase I clinical trial of ALN-HTT02 from Alynlam Pharmaceuticals. ...Finally, we provide a comprehensive listing of all currently registered and ongoing clinical trials in …
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing phase I clinical trial of ALN-HTT …
Huntington's disease.
Kent A. Kent A. Nurs Stand. 2004 Apr 21-27;18(32):45-51; quiz 52-3. doi: 10.7748/ns2004.04.18.32.45.c3596. Nurs Stand. 2004. PMID: 15132037 Review.
Huntington's disease is a complex degenerative disorder that affects the central nervous system. ...This article discusses the cause and symptoms, explains the method of diagnosis and outlines the role of the nurse in caring for patients with Huntington's …
Huntington's disease is a complex degenerative disorder that affects the central nervous system. ...This article discusses the …
Ubiquitin-modifying enzymes in Huntington's disease.
Sap KA, Geijtenbeek KW, Schipper-Krom S, Guler AT, Reits EA. Sap KA, et al. Front Mol Biosci. 2023 Feb 8;10:1107323. doi: 10.3389/fmolb.2023.1107323. eCollection 2023. Front Mol Biosci. 2023. PMID: 36926679 Free PMC article. Review.
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the N-terminus of the HTT gene. ...The soluble mHTT protein is associated with several ubiquitin-modifying enzymes, and various ubiquitin-modifying enzymes have been identi …
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the N-terminus of the HTT gene. …
Huntington's Disease Clinical Trials Update: September 2024.
Farag M, Tabrizi SJ, Wild EJ. Farag M, et al. J Huntingtons Dis. 2024 Nov;13(4):409-418. doi: 10.1177/18796397241293955. Epub 2024 Oct 26. J Huntingtons Dis. 2024. PMID: 39973379
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing extension study of PTC518 from PTC Therapeutics, including 12-month interim results from the parent study. ...Additionally, we provide a comprehensive listing of all current …
In this edition of the Huntington's Disease Clinical Trials Update, we expand on the ongoing extension study of PTC518 from PT …
Molecular Pathophysiological Mechanisms in Huntington's Disease.
Jurcau A. Jurcau A. Biomedicines. 2022 Jun 17;10(6):1432. doi: 10.3390/biomedicines10061432. Biomedicines. 2022. PMID: 35740453 Free PMC article. Review.
Huntington's disease is an inherited neurodegenerative disease described 150 years ago by George Huntington. ...However, due to the ubiquitous presence of huntingtin, astrocytes are also dysfunctional, and neuroinflammation may additionally contribute to H …
Huntington's disease is an inherited neurodegenerative disease described 150 years ago by George Huntington. ...However …
Huntington's disease: Brain imaging in Huntington's disease.
Johnson EB, Gregory S. Johnson EB, et al. Prog Mol Biol Transl Sci. 2019;165:321-369. doi: 10.1016/bs.pmbts.2019.04.004. Epub 2019 May 15. Prog Mol Biol Transl Sci. 2019. PMID: 31481169 Review.
Huntington's disease (HD) gene-carriers show prominent neuronal loss by end-stage disease, and the use of magnetic resonance imaging (MRI) has been increasingly used to quantify brain changes during earlier stages of the disease. ...
Huntington's disease (HD) gene-carriers show prominent neuronal loss by end-stage disease, and the use of magnetic resonance i …
A developmental component to Huntington's disease.
Ratié L, Humbert S. Ratié L, et al. Rev Neurol (Paris). 2024 May;180(5):357-362. doi: 10.1016/j.neurol.2024.04.001. Epub 2024 Apr 12. Rev Neurol (Paris). 2024. PMID: 38614929 Free article. Review.
Huntington's disease is a dominantly inherited disorder characterized by the dysfunction and death of cortical and striatal neurons. Striatal degeneration in Huntington's disease is due, at least in part, to defective cortical signalling to the striatu …
Huntington's disease is a dominantly inherited disorder characterized by the dysfunction and death of cortical and striatal ne …
Deutetrabenazine in the treatment of Huntington's disease.
Richard A, Frank S. Richard A, et al. Neurodegener Dis Manag. 2019 Feb;9(1):31-37. doi: 10.2217/nmt-2018-0040. Epub 2019 Jan 9. Neurodegener Dis Manag. 2019. PMID: 30624137 Review.
Deutetrabenazine (DTBZ) is a US FDA-approved treatment for chorea in Huntington's disease. The substitution of deuterium for hydrogen at specific positions imparts a longer half-life on DTBZ, allowing for less-frequent daily dosing. ...DTBZ significantly improved ch …
Deutetrabenazine (DTBZ) is a US FDA-approved treatment for chorea in Huntington's disease. The substitution of deuterium for h …
40,418 results
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