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Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Lancet. 2023 Jan 28;401(10373):281-293. doi: 10.1016/S0140-6736(22)02597-1. Epub 2022 Dec 22.
Lancet. 2023.
PMID: 36566761
Free PMC article.
Clinical Trial.
Health outcomes 3 months and 6 months after molnupiravir treatment for COVID-19 for people at higher risk in the community (PANORAMIC): a randomised controlled trial.
Harris V, Holmes J, Gbinigie-Thompson O, Rahman NM, Richards DB, Hayward G, Dorward J, Lowe DM, Standing JF, Breuer J, Khoo S, Petrou S, Hood K, Ahmed H, Carson-Stevens A, Nguyen-Van-Tam JS, Patel MG, Saville BR, Francis N, Thomas NPB, Evans P, Dobson M, Png ME, Lown M, van Hecke O, Jani BD, Hart ND, Butler D, Cureton L, Patil M, Andersson M, Coates M, Bateman C, Davies JC, Raymundo-Wood I, Ustianowski A, Yu LM, Hobbs FDR, Little P, Butler CC; PANORAMIC Trial Collaborative Group.
Harris V, et al.
Lancet Infect Dis. 2025 Jan;25(1):68-79. doi: 10.1016/S1473-3099(24)00431-6. Epub 2024 Sep 9.
Lancet Infect Dis. 2025.
PMID: 39265595
Free article.
Clinical Trial.
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A Viroimmunologic Model to Characterize the Antiviral Effect of Molnupiravir in Outpatients Infected With SARS-CoV-2: Implication for Treatment Duration.
Nguyen BT, Bertrand J, Agyeman AA, Zhang S, Yu LM, Harris V, Little P, Butler CC, Breuer J, Lowe DM, Standing JF, Guedj J; PANORAMIC study group.
Nguyen BT, et al.
J Infect Dis. 2025 Jul 11;231(6):e1080-e1090. doi: 10.1093/infdis/jiaf158.
J Infect Dis. 2025.
PMID: 40167341
Free PMC article.
Clinical Trial.
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