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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1957 1
1961 1
1962 1
1963 2
1964 3
1965 1
1966 2
1967 4
1968 6
1969 6
1970 5
1971 2
1972 4
1973 9
1974 11
1975 9
1976 6
1977 2
1978 5
1979 15
1980 17
1981 14
1982 13
1983 16
1984 21
1985 28
1986 36
1987 11
1988 31
1989 26
1990 22
1991 15
1992 31
1993 15
1994 24
1995 26
1996 40
1997 41
1998 36
1999 35
2000 43
2001 33
2002 30
2003 39
2004 45
2005 59
2006 59
2007 55
2008 58
2009 83
2010 77
2011 73
2012 85
2013 83
2014 92
2015 102
2016 101
2017 127
2018 114
2019 109
2020 139
2021 173
2022 163
2023 185
2024 185
2025 161
2026 1

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2,787 results

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Page 1
A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors.
Brands J, Bravo S, Jürgenliemke L, Grätz L, Schihada H, Frechen F, Alenfelder J, Pfeil C, Ohse PG, Hiratsuka S, Kawakami K, Schmacke LC, Heycke N, Inoue A, König G, Pfeifer A, Wachten D, Schulte G, Steinmetzer T, Watts VJ, Gomeza J, Simon K, Kostenis E. Brands J, et al. Among authors: inoue a. Nat Commun. 2024 Sep 3;15(1):7684. doi: 10.1038/s41467-024-51991-6. Nat Commun. 2024. PMID: 39227390 Free PMC article.
Valemetostat for patients with relapsed or refractory peripheral T-cell lymphoma (VALENTINE-PTCL01): a multicentre, open-label, single-arm, phase 2 study.
Zinzani PL, Izutsu K, Mehta-Shah N, Barta SK, Ishitsuka K, Córdoba R, Kusumoto S, Bachy E, Cwynarski K, Gritti G, Prica A, Jacobsen E, Feldman T, Guillermin Y, Ennishi D, Yoon DH, Domenech ED, Zain J, Wang J, Kim JS, Poel MV, Jin J, Wu S, Chen Y, Moriyama T, Inoue A, Nakajima K, Horwitz SM. Zinzani PL, et al. Among authors: inoue a. Lancet Oncol. 2024 Dec;25(12):1602-1613. doi: 10.1016/S1470-2045(24)00503-5. Epub 2024 Oct 29. Lancet Oncol. 2024. PMID: 39486433 Clinical Trial.
Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics.
Janetzko J, Kise R, Barsi-Rhyne B, Siepe DH, Heydenreich FM, Kawakami K, Masureel M, Maeda S, Garcia KC, von Zastrow M, Inoue A, Kobilka BK. Janetzko J, et al. Among authors: inoue a. Cell. 2022 Nov 23;185(24):4560-4573.e19. doi: 10.1016/j.cell.2022.10.018. Epub 2022 Nov 10. Cell. 2022. PMID: 36368322 Free PMC article.
Structure and dynamics determine G protein coupling specificity at a class A GPCR.
Casiraghi M, Wang H, Brennan PC, Habrian C, Hübner H, Schmidt MF, Maul L, Pani B, Bahriz SMFM, Xu B, Staffen N, Assafa TE, Chen B, White E, Sunahara RK, Inoue A, Xiang YK, Lefkowitz RJ, Isacoff EY, Nucci N, Gmeiner P, Lerch MT, Kobilka BK. Casiraghi M, et al. Among authors: inoue a. Sci Adv. 2025 Mar 21;11(12):eadq3971. doi: 10.1126/sciadv.adq3971. Epub 2025 Mar 19. Sci Adv. 2025. PMID: 40106559 Free PMC article.
Discovery of a functionally selective serotonin receptor (5-HT1AR) agonist for the treatment of pain.
Ullrich A, Schneider J, Braz JM, Neu E, Staffen N, Stanek M, Bláhová J, Hove T, Albert T, Allikalt A, Löber S, Bhardwaj K, Rodriguez-Rosado S, Fink E, Rasmussen T, Hübner H, Inoue A, Shoichet BK, Basbaum AI, Böttcher B, Weikert D, Gmeiner P. Ullrich A, et al. Among authors: inoue a. Sci Adv. 2025 Jun 20;11(25):eadv9267. doi: 10.1126/sciadv.adv9267. Epub 2025 Jun 18. Sci Adv. 2025. PMID: 40531992 Free PMC article.
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR.
Maemondo M, Inoue A, Kobayashi K, Sugawara S, Oizumi S, Isobe H, Gemma A, Harada M, Yoshizawa H, Kinoshita I, Fujita Y, Okinaga S, Hirano H, Yoshimori K, Harada T, Ogura T, Ando M, Miyazawa H, Tanaka T, Saijo Y, Hagiwara K, Morita S, Nukiwa T; North-East Japan Study Group. Maemondo M, et al. Among authors: inoue a. N Engl J Med. 2010 Jun 24;362(25):2380-8. doi: 10.1056/NEJMoa0909530. N Engl J Med. 2010. PMID: 20573926 Free article. Clinical Trial.
2,787 results