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34 results

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Page 1
An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status.
Takata H, Mitchell JL, Pacheco J, Pagliuzza A, Pinyakorn S, Buranapraditkun S, Sacdalan C, Leyre L, Nathanson S, Kakazu JC, Intasan J, Prueksakaew P, Chomchey N, Phanuphak N, de Souza M, Haddad EK, Rolland M, Tovanabutra S, Vasan S, Hsu DC, Chomont N, Trautmann L; RV254/SEARCH010; RV304/SEARCH013. Takata H, et al. Among authors: intasan j. Cell Host Microbe. 2023 Sep 13;31(9):1494-1506.e4. doi: 10.1016/j.chom.2023.08.012. Cell Host Microbe. 2023. PMID: 37708852 Free PMC article.
Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. Among authors: intasan j. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.
Acute HIV-1 infection viremia associate with rebound upon treatment interruption.
Mdluli T, Li Y, Pinyakorn S, Reeves DB, Cardozo-Ojeda EF, Yates A, Intasan J, Tipsuk S, Phanuphak N, Sacdalan C, Colby DJ, Kroon E, Crowell TA, Thomas R, Robb ML, Ananworanich J, de Souza M, Phanuphak P, Stieh DJ, Tomaka FL, Trautmann L, Ake JA, Hsu DC, Francisco LV, Vasan S, Rolland M. Mdluli T, et al. Among authors: intasan j. Med. 2022 Sep 9;3(9):622-635.e3. doi: 10.1016/j.medj.2022.06.009. Epub 2022 Jul 22. Med. 2022. PMID: 35870446 Free PMC article.
Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.
Cale EM, Bai H, Bose M, Messina MA, Colby DJ, Sanders-Buell E, Dearlove B, Li Y, Engeman E, Silas D, O'Sullivan AM, Mann B, Pinyakorn S, Intasan J, Benjapornpong K, Sacdalan C, Kroon E, Phanuphak N, Gramzinski R, Vasan S, Robb ML, Michael NL, Lynch RM, Bailer RT, Pagliuzza A, Chomont N, Pegu A, Doria-Rose NA, Trautmann L, Crowell TA, Mascola JR, Ananworanich J, Tovanabutra S, Rolland M; RV397 Study Group. Cale EM, et al. Among authors: intasan j. J Clin Invest. 2020 Jun 1;130(6):3299-3304. doi: 10.1172/JCI134395. J Clin Invest. 2020. PMID: 32182219 Free PMC article. Clinical Trial.
Neurologic signs and symptoms frequently manifest in acute HIV infection.
Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich S; SEARCH 010/RV254 Study Group. Hellmuth J, et al. Among authors: intasan j. Neurology. 2016 Jul 12;87(2):148-54. doi: 10.1212/WNL.0000000000002837. Epub 2016 Jun 10. Neurology. 2016. PMID: 27287217 Free PMC article.
Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection.
Peluso MJ, Colby DJ, Pinyakorn S, Ubolyam S, Intasan J, Trichavaroj R, Chomchey N, Prueksakaew P, Slike BM, Krebs SJ, Jian N, Robb ML, Phanuphak P, Phanuphak N, Spudich S, Ananworanich J, Kroon E; SEARCH010/RV254 Study Group. Peluso MJ, et al. Among authors: intasan j. J Int AIDS Soc. 2020 Jan;23(1):e25444. doi: 10.1002/jia2.25444. J Int AIDS Soc. 2020. PMID: 31953919 Free PMC article.
Impact of Acute HIV Infection and Early Antiretroviral Therapy on the Human Gut Microbiome.
Sortino O, Phanuphak N, Schuetz A, Ortiz AM, Chomchey N, Belkaid Y, Davis J, Mystakelis HA, Quiñones M, Deleage C, Ingram B, Rerknimitr R, Pinyakorn S, Rupert A, Robb ML, Ananworanich J, Brenchley J, Sereti I; RV254/SEARCH010 Study Group. Sortino O, et al. Open Forum Infect Dis. 2019 Aug 21;7(12):ofz367. doi: 10.1093/ofid/ofz367. eCollection 2020 Dec. Open Forum Infect Dis. 2019. PMID: 33324725 Free PMC article.
Neurodevelopmental outcomes in HIV-exposed-uninfected children versus those not exposed to HIV.
Kerr SJ, Puthanakit T, Vibol U, Aurpibul L, Vonthanak S, Kosalaraksa P, Kanjanavanit S, Hansudewechakul R, Wongsawat J, Luesomboon W, Ratanadilok K, Prasitsuebsai W, Pruksakaew K, van der Lugt J, Paul R, Ananworanich J, Valcour V; SEARCH 012 Study Team. Kerr SJ, et al. AIDS Care. 2014;26(11):1327-35. doi: 10.1080/09540121.2014.920949. Epub 2014 May 30. AIDS Care. 2014. PMID: 24878112 Free PMC article. Clinical Trial.
Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection.
Colby DJ, Trautmann L, Pinyakorn S, Leyre L, Pagliuzza A, Kroon E, Rolland M, Takata H, Buranapraditkun S, Intasan J, Chomchey N, Muir R, Haddad EK, Tovanabutra S, Ubolyam S, Bolton DL, Fullmer BA, Gorelick RJ, Fox L, Crowell TA, Trichavaroj R, O'Connell R, Chomont N, Kim JH, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV411 study group. Colby DJ, et al. Among authors: intasan j. Nat Med. 2018 Jul;24(7):923-926. doi: 10.1038/s41591-018-0026-6. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892063 Free PMC article.
Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption.
Colby DJ, Sarnecki M, Barouch DH, Tipsuk S, Stieh DJ, Kroon E, Schuetz A, Intasan J, Sacdalan C, Pinyakorn S, Grandin P, Song H, Tovanabutra S, Shubin Z, Kim D, Paquin-Proulx D, Eller MA, Thomas R, de Souza M, Wieczorek L, Polonis VR, Pagliuzza A, Chomont N, Peter L, Nkolola JP, Vingerhoets J, Truyers C, Pau MG, Schuitemaker H, Phanuphak N, Michael N, Robb ML, Tomaka FL, Ananworanich J. Colby DJ, et al. Among authors: intasan j. Nat Med. 2020 Apr;26(4):498-501. doi: 10.1038/s41591-020-0774-y. Epub 2020 Mar 23. Nat Med. 2020. PMID: 32235883 Clinical Trial.
34 results