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Page 1
Showing results for jam b
Search for Jamo B instead (1 results)
Human immune organoids to decode B cell response in healthy donors and patients with lymphoma.
Zhong Z, Quiñones-Pérez M, Dai Z, Juarez VM, Bhatia E, Carlson CR, Shah SB, Patel A, Fang Z, Hu T, Allam M, Hicks SL, Gupta M, Gupta SL, Weeks E, Vagelos SD, Molina A, Mulero-Russe A, Mora-Boza A, Joshi DJ, Sekaly RP, Sulchek T, Goudy SL, Wrammert J, Roy K, Boss JM, Coskun AF, Scharer CD, García AJ, Koff JL, Singh A. Zhong Z, et al. Nat Mater. 2025 Feb;24(2):297-311. doi: 10.1038/s41563-024-02037-1. Epub 2024 Nov 6. Nat Mater. 2025. PMID: 39506098
Immune organoids derived from peripheral blood mononuclear cells maintain GC B cells and plasma cells longer than tonsil-derived ones and exhibit unique B cell programming, including GC compartments, somatic hypermutation, immunoglobulin class switching and B …
Immune organoids derived from peripheral blood mononuclear cells maintain GC B cells and plasma cells longer than tonsil-derived ones …
The role of JAM-B in cancer and cancer metastasis (Review).
Zhao H, Yu H, Martin TA, Teng X, Jiang WG. Zhao H, et al. Oncol Rep. 2016 Jul;36(1):3-9. doi: 10.3892/or.2016.4773. Epub 2016 Apr 27. Oncol Rep. 2016. PMID: 27121546 Free PMC article. Review.
The junctional adhesion molecule B (JAM-B) is a multifunctional transmembrane protein, which belongs to the immunoglobulin superfamily (IgSF). ...In this review, we briefly focus on what is currently known about the structure, function, and mechanism of JA …
The junctional adhesion molecule B (JAM-B) is a multifunctional transmembrane protein, which belongs to the immunoglobu …
The JAM-B/c-src/MMP9 pathway is associated with progression and regulates the invasion of pancreatic cancer.
Zhang W, He R, Chen S, Zhang L, Cao G, Yang W, Li J. Zhang W, et al. J Cancer. 2020 Mar 5;11(11):3246-3255. doi: 10.7150/jca.40953. eCollection 2020. J Cancer. 2020. PMID: 32231730 Free PMC article.
Junctional adhesion molecule B (JAM-B) is a multifunctional transmembrane protein that plays an important role in tumor progression. JAM-B is significantly upregulated in gastric cancer, melanoma cell metastasis and oral squamous cell carcinoma. …
Junctional adhesion molecule B (JAM-B) is a multifunctional transmembrane protein that plays an important role in tumor …
Transcriptional and Post-Translational Regulation of Junctional Adhesion Molecule-B (JAM-B) in Leukocytes under Inflammatory Stimuli.
Day-Walsh PE, Keeble B, Pirabagar G, Fountain SJ, Kroon PA. Day-Walsh PE, et al. Int J Mol Sci. 2022 Aug 3;23(15):8646. doi: 10.3390/ijms23158646. Int J Mol Sci. 2022. PMID: 35955781 Free PMC article.
We show that JAM-B is expressed at both the mRNA and protein level in leukocytes. JAM-B protein is localised to the cytoplasm, Golgi apparatus and in the nucleus around ring-shaped structures. We also provide evidence that JAM-B nuclear l …
We show that JAM-B is expressed at both the mRNA and protein level in leukocytes. JAM-B protein is localised to …
Junctional adhesion molecules JAM-B and JAM-C promote autoimmune-mediated liver fibrosis in mice.
Hintermann E, Bayer M, Conti CB, Fuchs S, Fausther M, Leung PS, Aurrand-Lions M, Taubert R, Pfeilschifter JM, Friedrich-Rust M, Schuppan D, Dranoff JA, Gershwin ME, Manns MP, Imhof BA, Christen U. Hintermann E, et al. J Autoimmun. 2018 Jul;91:83-96. doi: 10.1016/j.jaut.2018.05.001. Epub 2018 May 9. J Autoimmun. 2018. PMID: 29753567
Therefore, localization and function of JAM-B and JAM-C were investigated in three mouse models of autoimmune-driven liver inflammation. ...Most importantly, AIH-mediated liver fibrosis was reduced in JAM-B(-/-) mice or when JAM-C was blo …
Therefore, localization and function of JAM-B and JAM-C were investigated in three mouse models of autoimmune-driven li …
Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles.
Brown DW, Wee P, Bhandari P, Bukhari A, Grin L, Vega H, Hejazi M, Sosnowski D, Ablack J, Clancy EK, Pink D, Kumar J, Solis Ares MP, Lamb S, Quevedo R, Rawal B, Elian F, Rana N, Morales L, Govindasamy N, Todd B, Delmage A, Gupta S, McMullen N, MacKenzie D, Beatty PH, Garcia H, Parmar M, Gyoba J, McAllister C, Scholz M, Duncan R, Raturi A, Lewis JD. Brown DW, et al. Cell. 2024 Sep 19;187(19):5357-5375.e24. doi: 10.1016/j.cell.2024.07.023. Epub 2024 Sep 10. Cell. 2024. PMID: 39260374 Free article.
Lack of junctional adhesion molecule (JAM)-B ameliorates experimental autoimmune encephalomyelitis.
Tietz S, Périnat T, Greene G, Enzmann G, Deutsch U, Adams R, Imhof B, Aurrand-Lions M, Engelhardt B. Tietz S, et al. Brain Behav Immun. 2018 Oct;73:3-20. doi: 10.1016/j.bbi.2018.06.014. Epub 2018 Jun 18. Brain Behav Immun. 2018. PMID: 29920328 Free article.
This prompted us to investigate, if JAM-B also mediates CD4(+) T-cell migration across the BBB. We first ensured that encephalitogenic T cells can bind to JAM-B in vitro and next compared EAE pathogenesis in JAM-B(-/-) C57BL/6J mice and t …
This prompted us to investigate, if JAM-B also mediates CD4(+) T-cell migration across the BBB. We first ensured that encephal …
JAM-A overexpression is related to disease progression in diffuse large B-cell lymphoma and downregulated by lenalidomide.
Xu PP, Sun YF, Fang Y, Song Q, Yan ZX, Chen Y, Jiang XF, Fei XC, Zhao Y, Leboeuf C, Li B, Wang CF, Janin A, Wang L, Zhao WL. Xu PP, et al. Sci Rep. 2017 Aug 7;7(1):7433. doi: 10.1038/s41598-017-07964-5. Sci Rep. 2017. PMID: 28785100 Free PMC article.
JAM-A maintained B-lymphoma cell stemness and was associated with cell invasion and epithelial-to-mesenchymal transition both in vitro and in vivo. ...Lenalidomide downregulated JAM-A and downstream NODAL expression, resulting in inhibition of B-lympho …
JAM-A maintained B-lymphoma cell stemness and was associated with cell invasion and epithelial-to-mesenchymal transition both …
Lack of junctional adhesion molecule (JAM)-B traps CD8 T cells in CNS border zones and ameliorates autoimmune neuroinflammation.
Pareja J, Aydin S, Zbinden M, Bouillet E, Zollinger N, Theivendram V, Fahmi A, Pleskač P, Barcos S, Paas F, Kloster F, Blázquez AM, Fonta N, Merkler D, Deutsch U, Engelhardt B. Pareja J, et al. Acta Neuropathol Commun. 2025 May 26;13(1):117. doi: 10.1186/s40478-025-02021-z. Acta Neuropathol Commun. 2025. PMID: 40420242 Free PMC article.
We generated JAM-B-deficient ODC-OVA mice (ODC-OVA; JAM-B(KO) mice) and compared CD8 T cell mediated autoimmune neuroinflammation to their ODC-OVA; JAM-B(WT) littermates. ...Surprisingly, lack of JAM-B did not affect CD8 T c …
We generated JAM-B-deficient ODC-OVA mice (ODC-OVA; JAM-B(KO) mice) and compared CD8 T cell mediated autoimmune …
593 results