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Year Number of Results
2006 4
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2012 1
2013 1
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2019 1
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2021 1
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2025 26

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83 results

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Page 1
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, Reiman EM, Haroutunian V, Wang M, Schadt E, Zhang B, Dickson DW, Ertekin-Taner N, Golde TE, Petyuk VA, De Jager PL, Bennett DA, Wingo TS, Rangaraju S, Hajjar I, Shulman JM, Lah JJ, Levey AI, Seyfried NT. Johnson ECB, et al. Nat Med. 2020 May;26(5):769-780. doi: 10.1038/s41591-020-0815-6. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284590 Free PMC article.
Multiscale proteomic modeling reveals protein networks driving Alzheimer's disease pathogenesis.
Wang E, Yu K, Cao J, Wang M, Katsel P, Song WM, Wang Z, Li Y, Wang X, Wang Q, Xu P, Yu G, Zhu L, Geng J, Habibi P, Qian L, Tuck T, Li A, Tcw J, Roussos P, Brennand KJ, Haroutunian V, Johnson ECB, Seyfried NT, Levey AI, Bennett DA, Peng J, Cai D, Zhang B. Wang E, et al. Among authors: johnson ecb. Cell. 2025 Oct 30;188(22):6186-6204.e13. doi: 10.1016/j.cell.2025.08.038. Epub 2025 Sep 25. Cell. 2025. PMID: 41005309 Free article.
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
Shen Y, Timsina J, Heo G, Beric A, Ali M, Wang C, Yang C, Wang Y, Western D, Liu M, Gorijala P, Budde J, Do A, Liu H, Gordon B, Llibre-Guerra JJ, Joseph-Mathurin N, Perrin RJ, Maschi D, Wyss-Coray T, Pastor P, Renton AE, Surace EI, Johnson ECB, Levey AI, Alvarez I, Levin J, Ringman JM, Allegri RF, Seyfried N, Day GS, Wu Q, Fernández MV, Tarawneh R, McDade E, Morris JC, Bateman RJ, Goate A; Dominantly Inherited Alzheimer Network; Ibanez L, Sung YJ, Cruchaga C. Shen Y, et al. Among authors: johnson ecb. Cell. 2024 Oct 31;187(22):6309-6326.e15. doi: 10.1016/j.cell.2024.08.049. Epub 2024 Sep 26. Cell. 2024. PMID: 39332414 Free PMC article.
Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity.
Moscoso A, Heeman F, Raghavan S, Costoya-Sánchez A, van Essen M, Mainta I, Camacho V, Rodríguez-Fonseca O, Silva-Rodríguez J, Perissinotti A, Gu Y, Yun J, Peretti D, Ribaldi F, Coomans EM, Brum WS, Grothe MJ, Aguiar P, Bischof GN, Drzezga A, Seo SW, Villeneuve S, Malpetti M, O'Brien JT, Rowe JB, van de Giessen EM, Ossenkoppele R, Jagust WJ, Smith R, Hansson O, Frisoni GB, Garibotto V, Soleimani-Meigooni DN, Carrillo M, Dickerson BC, La Joie R, Rabinovici GD, Apostolova LG, LaMontagne PJ, Pontecorvo MJ, Johnson KA, Sperling RA, Weiner MW, Petersen RC, Jack CR Jr, Vemuri P, Schöll M; PREVENT-AD Research Group, the Harvard Aging Brain Study, the LEADS Consortium, and the Alzheimer’s Disease Neuroimaging Initiative. Moscoso A, et al. JAMA. 2025 Jul 15;334(3):229-242. doi: 10.1001/jama.2025.7817. JAMA. 2025. PMID: 40522652
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease.
Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, Karch C, Schindler SE, Rhinn H, Johnson ECB, Oh HS, Rutledge JE, Dammer EB, Seyfried NT, Wyss-Coray T, Harari O, Cruchaga C. Sung YJ, et al. Among authors: johnson ecb. Sci Transl Med. 2023 Jul 5;15(703):eabq5923. doi: 10.1126/scitranslmed.abq5923. Epub 2023 Jul 5. Sci Transl Med. 2023. PMID: 37406134 Free PMC article.
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.
Llibre-Guerra JJ, Fernandez MV, Joseph-Mathurin N, Bian S, Carter K, Li Y, Aschenbrenner AJ, Pottier C, Sigurdson W, McDade E, Gordon BA, Renton AE, Benzinger TLS, Ibañez L, Barthelemy N, Johnson M, Hassenstab J, Wang G, Goate AM, Western D, Wang C, Hobbs D, Daniels A, Karch C, Morris JC, Cruchaga C, Johnson ECB, Bateman RJ; Dominantly Inherited Alzheimer Network. Llibre-Guerra JJ, et al. Among authors: johnson ecb. Nat Med. 2025 Apr;31(4):1267-1275. doi: 10.1038/s41591-025-03494-0. Epub 2025 Feb 10. Nat Med. 2025. PMID: 39930140
The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging.
Imam F, Saloner R, Vogel JW, Krish V, Abdel-Azim G, Ali M, An L, Anastasi F, Bennett D, Pichet Binette A, Boxer AL, Bringmann M, Burns JM, Cruchaga C, Dage JL, Farinas A, Ferrucci L, Finney CA, Frasier M, Hansson O, Hohman TJ, Johnson ECB, Kivimaki M, Korologou-Linden R, Ruiz Laza A, Levey AI, Liepelt-Scarfone I, Lu L, Mattsson-Carlgren N, Middleton LT, Nho K, Oh HS, Petersen RC, Reiman EM, Robinson O, Rothstein JD, Saykin AJ, Shvetcov A, Slawson C, Smets B, Suárez-Calvet M, Tijms BM, Timmers M, Vieira F, Vilor-Tejedor N, Visser PJ, Walker KA, Winchester LM, Wyss-Coray T, Yang C, Bose N, Lovestone S; Global Neurodegeneration Proteomics Consortium (GNPC). Imam F, et al. Among authors: johnson ecb. Nat Med. 2025 Aug;31(8):2556-2566. doi: 10.1038/s41591-025-03834-0. Epub 2025 Jul 15. Nat Med. 2025. PMID: 40665048 Free PMC article.
Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer's disease.
Frick EA, Emilsson V, Jonmundsson T, Steindorsdottir AE, Johnson ECB, Puerta R, Dammer EB, Shantaraman A, Cano A, Boada M, Valero S, García-González P, Gudmundsson EF, Gudjonsson A, Pitts R, Qiu X, Finkel N, Loureiro JJ, Orth AP, Seyfried NT, Levey AI, Ruiz A, Aspelund T, Jennings LL, Launer LJ, Gudmundsdottir V, Gudnason V. Frick EA, et al. Among authors: johnson ecb. Nat Aging. 2024 Oct;4(10):1446-1464. doi: 10.1038/s43587-024-00693-1. Epub 2024 Aug 21. Nat Aging. 2024. PMID: 39169269 Free PMC article.
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, Zhang B, Gaiteri C, Bennett DA, Gearing M, Wingo TS, Wingo AP, Lah JJ, Levey AI, Seyfried NT. Johnson ECB, et al. Nat Neurosci. 2022 Feb;25(2):213-225. doi: 10.1038/s41593-021-00999-y. Epub 2022 Feb 3. Nat Neurosci. 2022. PMID: 35115731 Free PMC article.
83 results