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. 2015 Aug:34:116-9.
doi: 10.1016/j.anaerobe.2015.05.003. Epub 2015 May 18.

Occurrence and new mutations involved in rifampicin-resistant Propionibacterium acnes strains isolated from biofilm or device-related infections

Ulrika Furustrand Tafin  1 , Guillaume Ghislain Aubin  2 , Gerhard Eich  3 , Andrej Trampuz  4 , Stéphane Corvec  5
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Occurrence and new mutations involved in rifampicin-resistant Propionibacterium acnes strains isolated from biofilm or device-related infections

Ulrika Furustrand Tafin et al. Anaerobe. 2015 Aug.

Abstract

We described for the first time the amino acid substitutions conferring rifampicin resistance in eight Propionibacterium acnes strains isolated from patients with biofilm or device-related infections. We identified different mutations in cluster I and one mutation, never reported, in cluster II of the rpoB gene (I480V) associated with the most frequent one in cluster I (S442L). Half of the patients previously received treatment with rifampicin.

Keywords: Biofilm; Foreign-body infection; Propionibacterium acnes; Resistance; Rifampicin.

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