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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1948 1
1952 1
1953 1
1960 1
1961 2
1962 1
1963 3
1964 2
1965 1
1967 1
1968 2
1969 5
1970 4
1971 2
1972 3
1973 1
1974 3
1976 4
1978 1
1979 1
1980 3
1981 4
1982 6
1983 5
1984 6
1985 7
1986 13
1987 16
1988 18
1989 17
1990 21
1991 18
1992 20
1993 16
1994 15
1995 26
1996 16
1997 14
1998 9
1999 12
2000 13
2001 17
2002 14
2003 17
2004 16
2005 20
2006 20
2007 16
2008 17
2009 26
2010 24
2011 29
2012 41
2013 38
2014 56
2015 41
2016 58
2017 67
2018 47
2019 54
2020 67
2021 82
2022 53
2023 43
2024 55
2025 55
2026 1

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1,167 results

Results by year

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Page 1
Drugging an undruggable pocket on KRAS.
Kessler D, Gmachl M, Mantoulidis A, Martin LJ, Zoephel A, Mayer M, Gollner A, Covini D, Fischer S, Gerstberger T, Gmaschitz T, Goodwin C, Greb P, Häring D, Hela W, Hoffmann J, Karolyi-Oezguer J, Knesl P, Kornigg S, Koegl M, Kousek R, Lamarre L, Moser F, Munico-Martinez S, Peinsipp C, Phan J, Rinnenthal J, Sai J, Salamon C, Scherbantin Y, Schipany K, Schnitzer R, Schrenk A, Sharps B, Siszler G, Sun Q, Waterson A, Wolkerstorfer B, Zeeb M, Pearson M, Fesik SW, McConnell DB. Kessler D, et al. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):15823-15829. doi: 10.1073/pnas.1904529116. Epub 2019 Jul 22. Proc Natl Acad Sci U S A. 2019. PMID: 31332011 Free PMC article.
Maintenance or Discontinuation of Antidepressants in Primary Care.
Lewis G, Marston L, Duffy L, Freemantle N, Gilbody S, Hunter R, Kendrick T, Kessler D, Mangin D, King M, Lanham P, Moore M, Nazareth I, Wiles N, Bacon F, Bird M, Brabyn S, Burns A, Clarke CS, Hunt A, Pervin J, Lewis G. Lewis G, et al. Among authors: kessler d. N Engl J Med. 2021 Sep 30;385(14):1257-1267. doi: 10.1056/NEJMoa2106356. N Engl J Med. 2021. PMID: 34587384 Clinical Trial.
Psychological therapies for treatment-resistant depression in adults.
Ijaz S, Davies P, Williams CJ, Kessler D, Lewis G, Wiles N. Ijaz S, et al. Among authors: kessler d. Cochrane Database Syst Rev. 2018 May 14;5(5):CD010558. doi: 10.1002/14651858.CD010558.pub2. Cochrane Database Syst Rev. 2018. PMID: 29761488 Free PMC article.
Gone Too Soon: priorities for action to prevent premature mortality associated with mental illness and mental distress.
O'Connor RC, Worthman CM, Abanga M, Athanassopoulou N, Boyce N, Chan LF, Christensen H, Das-Munshi J, Downs J, Koenen KC, Moutier CY, Templeton P, Batterham P, Brakspear K, Frank RG, Gilbody S, Gureje O, Henderson D, John A, Kabagambe W, Khan M, Kessler D, Kirtley OJ, Kline S, Kohrt B, Lincoln AK, Lund C, Mendenhall E, Miranda R, Mondelli V, Niederkrotenthaler T, Osborn D, Pirkis J, Pisani AR, Prawira B, Rachidi H, Seedat S, Siskind D, Vijayakumar L, Yip PSF. O'Connor RC, et al. Among authors: kessler d. Lancet Psychiatry. 2023 Jun;10(6):452-464. doi: 10.1016/S2215-0366(23)00058-5. Epub 2023 May 11. Lancet Psychiatry. 2023. PMID: 37182526 Free article. Review.
Pharmacological and psychotherapeutic interventions for management of obsessive-compulsive disorder in adults: a systematic review and network meta-analysis.
Skapinakis P, Caldwell DM, Hollingworth W, Bryden P, Fineberg NA, Salkovskis P, Welton NJ, Baxter H, Kessler D, Churchill R, Lewis G. Skapinakis P, et al. Among authors: kessler d. Lancet Psychiatry. 2016 Aug;3(8):730-739. doi: 10.1016/S2215-0366(16)30069-4. Epub 2016 Jun 16. Lancet Psychiatry. 2016. PMID: 27318812 Free PMC article.
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition.
Hofmann MH, Gmachl M, Ramharter J, Savarese F, Gerlach D, Marszalek JR, Sanderson MP, Kessler D, Trapani F, Arnhof H, Rumpel K, Botesteanu DA, Ettmayer P, Gerstberger T, Kofink C, Wunberg T, Zoephel A, Fu SC, Teh JL, Böttcher J, Pototschnig N, Schachinger F, Schipany K, Lieb S, Vellano CP, O'Connell JC, Mendes RL, Moll J, Petronczki M, Heffernan TP, Pearson M, McConnell DB, Kraut N. Hofmann MH, et al. Among authors: kessler d. Cancer Discov. 2021 Jan;11(1):142-157. doi: 10.1158/2159-8290.CD-20-0142. Epub 2020 Aug 19. Cancer Discov. 2021. PMID: 32816843 Free PMC article.
A systematic review of the clinical effectiveness and cost-effectiveness of pharmacological and psychological interventions for the management of obsessive-compulsive disorder in children/adolescents and adults.
Skapinakis P, Caldwell D, Hollingworth W, Bryden P, Fineberg N, Salkovskis P, Welton N, Baxter H, Kessler D, Churchill R, Lewis G. Skapinakis P, et al. Among authors: kessler d. Health Technol Assess. 2016 Jun;20(43):1-392. doi: 10.3310/hta20430. Health Technol Assess. 2016. PMID: 27306503 Free PMC article.
Cancer and herbs.
Kessler DA. Kessler DA. N Engl J Med. 2000 Jun 8;342(23):1742-3. doi: 10.1056/NEJM200006083422309. N Engl J Med. 2000. PMID: 10841878 No abstract available.
Reply by Authors.
Rojo Domingo M, Do DD, Conlin CC, Bagrodia A, Barrett T, Baxter MT, Cooperberg M, Feng F, Hahn ME, Harisinghani M, Hollenberg G, Javier-Desloges J, Kallis K, Kamran S, Kane CJ, Kessler D, Kuperman J, Lee KL, Levine J, Liss MA, Margolis DJA, Matthews I, Murphy PM, Nakrour N, Ohliger M, Ollison C, Osinski T, Pamatmat AJ, Pompa IR, Rakow-Penner R, Roberts JL, Shabaik AS, Song Y, Song D, Tempany CM, Trecarten S, Wehrli N, Weinberg EP, Woolen S, Xu G, Zhong AY, Dale AM, Seibert TM. Rojo Domingo M, et al. Among authors: kessler d. J Urol. 2025 Sep;214(3):270-271. doi: 10.1097/JU.0000000000004633. Epub 2025 Jun 24. J Urol. 2025. PMID: 40552623 No abstract available.
1,167 results